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H Galera

Publications and source records attributed to H Galera.

At least 19 recordsLinked to original sources
PubMed1992

Immunocytochemical study of the ultimobranchial tubule in Wistar rats.

A systematic immunohistochemical study of the ultimobranchial tubule (UBT) has been carried out in 45 Wistar rats of different ages (0, 5, 10, 15, 20, 25, 30, 60 and 120 days). The existence of calcitonin immunoreactive cells in the UBT wall has been demonstrated in a 5-days old rat. In addition, immunohistochemical studies for thyroglobulin revealed positive staining in follicular cells connected to the UBT and, occasionally, in isolated cells lying within solid clusters from the UBT. These last results together with the continued and repeated existence of numerous mitosis and PAS (+) microfollicles, apparently rising from the UBT, support the hypothesis that the ultimobranchial body (UBB) may contribute partially to the formation of a part of the follicular component.

Animals↗
PubMed1991

The effect of HeNe laser radiation on the thyroid gland of the rat.

Although laser irradiation is becoming common practice in medicine, there is not always a clear understanding of the possible side-effects. The present report is a light and electron microscopic study of the effects of fixed low intensity doses of soft HeNe laser on the thyroid of Wistar rats. The immediate effects are mild multifocal degenerative changes; these lesions recover in less than 3 months. Long-term lesions are identified only by electron microscopy; they consist of an increased number of peroxisomes and free or intramitochondrial crystalline structures. We discuss the laser's hypothetical functions.

Animals↗
PubMed1990

Effects of treatment with noradrenaline and isoproterenol on the excretory portion of the submaxillary gland in the rat: an ultrastructural study.

The aim of this study is to evaluate the modification of the excretory portion and its comparison with the acinus, on stimulating the rat submaxillary gland with noradrenaline and isoproterenol. Stimulation of the submaxillary gland with these drugs for a period of 10 min produces different effects in the acinus and excretory portion. The secretory granules do not show reorganisation of their contents after stimulation with isoproterenol, while in the acinus the material is reorganised forming concentric laminae. After stimulation with noradrenaline, the acinar lumen increases its diameter with respect to the control groups, while this same stimulus does not modify the diameter of the ductal lumen. After stimulation with noradrenaline, the extracellular spaces are consistently obliterated in all ducts except the striated duct, in which the behaviour is variable as in the acinus. In these two latter cases, the extracellular spaces are visible in some cases and not in others. Stimulation with noradrenaline is a potent stimulus of synthesis in both the granular undulated duct and the striated undulated duct, while in the acinus this effect is produced by isoproterenol.

Animals↗
PubMed1990

A morphometric study of the secretory granules of the granular duct in the submaxillary gland of the rat following stimulation with noradrenaline and isoproterenol.

In the present work, we carry out a morphometric analysis, at ultrastructural level, of the secretory granules of the granular undulated duct of the submaxillary gland of the rat, under basal conditions (Control Group or I), following stimulation for 10 minutes with 2 mg/100 g weight of Isoproterenol (Group II), and following stimulation with 2 gammas/100 g weight of Noradrenalin for the same time as in the former case. It is seen that in general, Noradrenalin produces the appearance of a greater number of small granules than does Isoproterenol or the control group; and that Isoproterenol induces the presence of larger-sized granules than does Noradrenalin.

Animals↗
PubMed1989

Demonstration of sugar residues in the ultimobranchial tubule and thyroid C-cells of the rat using peroxidase labelled lectins.

The distribution of various sugars, that contribute to the composition of the carbohydrate components of the glycoprotein in the ultimobranchial tubule and the thyroid C-cells has been studied, using eight peroxidase-labelled lectins (Dolichos biblorus, Glycine max, Bauhinia purpurea, Helix pomatia, Arachis hipogaea, Ulex europaeus I, Limax flavus and Sophora japonica). The results obtained seem to show that there are receptors for Dolichos biflorus, Glycine max, Bauhinia purpurea, Helix pomatia, Arachis hipogaea, Ulex europaeus I and Limax flavus in the ultimobranchial tubule, suggesting the existence of N-acetylgalactosamine, galactose, L-fucose and sialic acid. However, the C-cells show only a positive reaction with Ulex europaeus I indicating the existence of fucosyl residues in those cells. All these findings support the contention that the ultimobranchial body might contribute decisively not only to the formation of C-cells but also, partially, to the constitution of certain follicular cells.

Animals↗
PubMed1988

[Study of isochromosomes of the long arms of the X chromosome].

A clinical and cytogenetic study of 10 patients with chromosome formula of isochromosome in the long arms of the X in all the cells or in a mosaic with another cell line is made. Cases os isochromosomes, so far reported, differentiating them into monocentric and dicentric, after applying techniques of C-banding to them, have been review. Finally a clinical study of the cases 46,Xi (Xq) is made.

Chromosome Banding↗
PubMed1986

Hürthle cell and mitochondrion-rich cell tumors. A clinicopathologic study.

Hürthle cells are large eosinophilic thyroid cells that contain a large number of mitochondria with a high content of oxidative enzymes. In the last 10 years several reports have emphasized the disagreement over the morphologic features, biologic behavior and treatment of Hürthle cell tumors. The authors reviewed the clinical and pathologic features of 28 patients with Hürthle cell and mitochondrion-rich cell tumors (16 adenomas, 10 follicular carcinomas, and 2 papillary carcinomas) and present electron microscopic, immunohistochemical, and morphometric data. The results suggest that there is a correlation between biologic behavior and pathologic findings, that tumor size should not be considered a special conditioning factor in order to assign a biologic behavior, that nuclear size and anisokaryosis are not an absolute criteria for diagnosing malignancy, and finally, that electron microscopic examination is not useful in separating benign from malignant Hürthle cell tumors.

Adenocarcinoma↗
PubMed1982

[Pathological anatomy of neoplasms of the pancreas. I. Tumors of the exocrine pancreas].

The authors make a review of the exocrine pancreas tumors describing the main clinical, pathological and histogenetic features. The benign neoplasms develop generally from the ductal epithelium and may be cystic or mucinous, the last type suffering some times a malignant transformation. The malignant tumors are very common; histogenetically they may be ductal, acinar or of uncertain origin. Tumor localization, size and invasion are to be taken into consideration for the prognosis.

Adenoma↗
PubMed1981

Oat cell carcinoma of the oesophagus. Case description and review of the literature.

The small oat cell type of carcinoma is only rarely seen in extrapulmonary sites. To date, nineteen cases have been described in the oesophagus, almost all by Japanese authors. In this report we review the relevant literature and add one more case of pure type to the total. The histopathological, histochemical and ultrastructural findings and the similarity of this tumour to the oat cell bronchial carcinoma, lead one to propose that it originates in the cells of the APUD series, which have been demonstrated in the normal oesophageal epithelium. Thus is represents on endocrine carcinoma of the oesophagus.

APUD Cells↗
PubMed1981

'Benign' fibrous histiocytoma of the trachea.

Fibro-histiocytic neoplasms are uncommon in the respiratory tract. This paper presents a clinical and histological description of a case of fibrous histiocytoma at the level of the third tracheal ring. This cases shares some features with the four cases previously described, viz., the growth occurs mainly in young adults; recurrences are common; and all have shown similar benign histological patterns. Ultrastructural investigations confirmed the fibro-histiocytic nature of the neoplasm.

Adolescent↗
PubMed1981

Partial trisomy of chromosome 18 (pter leads to q11): a discussion on the identification of the critical segment.

Partial trisomy for the short arm and the proximal region of the long arm of chromosome 18 was observed in a male child of 4 years of age. The trisomy appeared de novo as a free, practically metacentric chromosome. A review of other cases of partial trisomy 18 suggests that there is a critical segment of the chromosome responsible for typical phenotype of the trisomy 18. In this report we add the description of a new case to the work already carried out in the delimitation of this critical segment.

Abnormalities, Multiple↗