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H Galloway

Publications and source records attributed to H Galloway.

7 recordsLinked to original sources
PubMed1983

Acetylation of sulphanilamide in four marsupials and a monotreme.

1. The urinary metabolites of sulphanilamide (100 mg/kg, i.p.) have been studied in four marsupials (the Tasmanian devil, brushtail possum, pademelon and barred bandicoot), a monotreme (the echidna) and a eutherian (the rat). 2. All species excreted some unchanged sulphanilamide (20-30% of dose in 24 h). The major urinary metabolite in the devil, possum and pademelon was N4-acetylsulphanilamide (6-17%). This was less than that excreted by the rat (40%). These three marsupials and the rat also excreted small amounts of N1-acetyl and N1, N4-diacetylsulphanilamide. 3. The bandicoot and echidna were virtually unable to acetylate sulphanilamide, unlike the 16 other species of animals and birds in which this has been studied. The reason for this metabolic defect is unknown.

Acetylation↗
PubMed1982

Normality and reliability in the clinical assessment of backache.

Backache is common yet its routine medical assessment is imprecise, unreliable, and poorly interpreted. Reproducibility studies on 475 patients improved the reliability of clinical interview and examination in backache, while studies of 335 normal subjects defined the limits of normality. Assessment of nerve function was found to be reliable but assessment of the back itself had to be considerably modified and examination improved by incorporating actual measurements. The validity and clinical utility of the information were analysed to determine the minimum amount of information which should be collected to permit clear diagnosis and management.

Adult↗