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Biomedical subjects

H Glanz

Publications and source records attributed to H Glanz.

72 records · Page 4Linked to original sources
PubMed1981

[Ocular motility disturbances following frontal sinus operations (author's transl)].

160 patients were operated on due to injuries, inflammations or tumors of the frontal sinus. There occurred in 23.8% temporary and 8.1% permanent double vision. By synoptometric investigations the origin of these disturbances of the ocular motility was analysed and separated into several groups. Different reasons for the cause of the motility-disturbances are given, their prophylaxes and therapy are discussed. The consequence of these investigations is that the method of operation should be modified to an osteoplastic way.

Diplopia↗
PubMed1979

[Ionising rays and laryngeal carcinomas (author's transl)].

Review of the literature and report of a new care of laryngeal cancer after irradiation of a benign lesion of the neck. These cases obviously become rare since benign lesions are no longer irradiated. Today the risk of inducing a second carcinoma by a successful irradiation of the first tumor becomes more important. A study of 109 patients, irradiated for laryngeal carcinoma and surviving with no evidence of disease for a period of at least 5 years has been performed. 8 of these patients developed a second primary in the previously irradiated area after 7-15 years. These second carcinomas are not rare if one considers that most patients with laryngeal carcinoma are 60-70 years old and therefore the life expectance on an average is low. These facts should be taken into consideration when deciding between surgical or radiation therapy in younger patients with high life expectance.

Aged↗
PubMed1979

[Multiple malignant tumours in patients with laryngeal cancers (author's transl)].

Of 496 patients with laryngeal cancer, 45 developed second primary cancers in other organs. In 7 patients triple primary tumours were detected. Multiple malignant tumours in the region of the upper respiratory and alimentary tracts were frequent; especially noticeable was the combination of larynx- and lung tumours. The prognosis of the second cancers is bad, since these tumours are diagnosed late and the patients are usually very old. Of patients, who were cured of the first cancers, one in five developed a new cancer after the five year limit. The follow up examinations must therefore be continued beyond the five year limit.

Adult↗
PubMed1979

[Immediate reconstruction of the fractured anterior wall of the frontal sinus (author's transl)].

Report on 83 cases of frontal sinus wall fractures. All cases including those with cerebrospinal liquorrhea, early meningitis and brain tissue prolaps were operated on as early as possible, and the anterior wall of the frontal sinus reconstructed immediately by means of multiple wire osteosyntheses. The follow up shows that even very small bone fragments are built in again, and no resorption ensues. X-rays and bone-scintigramms show that these membranously preformed bone fragments reunite well and consequently underly other healing conditions than chondrally ossified bones. Until now, no endocranial complications at all have appeared. The procedure although primarily timeconsuming, has proven to be superior to the Riedel obliteration method with following plastic restoration of the profile as regards the cosmetic results and the length of treatment.

Frontal Bone↗
PubMed1978

[Adenoid-cystic carcinoma of the larynx (author's transl)].

Report on 5 cases of adenoidcystic carcinoma of the larynx and review of the literature, containing about 60 further reports. About 80% of these tumors arise in the subglottice laryngo-tracheal transition region, 20% in the ventricular cord and the epiglottis. The vocal cords containing no mucus glands are never the origin of adenoid cystic carcinomas. These tumors grow under an intact mucosa and reach very often an enormous extension until dyspnoea, dysphagia and recurrent never paresis lead to diagnosis. The clinical course of these tumors ist not preditable--even not by their histological structure. In some cases the outcome is rapidely fatal by local growth and metastases, in others a many year long survival can be reached, but there exists no reliable report on a "cured" adenoid cystic carcinoma of the larynx. By radical surgery only better results can be expected. Irradiation produces long lasting remissions in some cases.

Adult↗
PubMed1978

[Sarcomalike patterns in laryngeal carcinoma (pseudosarcoma, carcinosarcoma, spindle-cell-carcinoma, pleomorphic carcioma (author's transl)].

Report on 5 cases of so called carcinosarcomas of the larynx and hypopharynx and review of literature. These polypoid tumors have a small epidermoid carcinomatous part and a major part with sarcoma like appearance. The sarcomatoid tissue resembles to fibrosarcomas or some undifferentiated pleomorphic sarcoma. Observations of a gradual transition from the epithelial tumor cells to cells with a mesodermal appearance show that these tumors are varieties of squamous cell carcinomas (spindle cell or pleomorphic variety) and not "combination"--or "collision-tumors", "carcinosarcomas" or "seudosarcomas". These tumors appear in the larynx predominantly in man, at the same sites and in the same ageclasses as common squamous cell cancers and are not less malignant. The sarcomatoid tissue can arise at the beginning of the disease or at a later stage it can appear or disappear after operation or irradiation. The reason for this change of cellular structure is unknown.

Aged↗
PubMed1978

[Metastases to the larynx (author's transl)].

Four cases of metastases to the larynx are reported and 43 similarly reported in the literature are reviewed. Most were metastases from hypernephromas or melanomas, producing supraglottic soft tissue tumours. Metastases from bronchial and mammary carcinomas in most cases are "bone metastases" within the laryngeal skeleton. Metastases in the larynx from all other malignancies are extremely rare. The clinical picture is variable and can cause considerable diagnostic difficulty especially in laryngeal skeletal metastases. Solitary metastases can be successfully treated by surgery and irradiation.

Adenocarcinoma↗
PubMed1978

[Fractures of the orbital floor (author's transl)].

Within 5 years (1973--1977) 171 facial fractures were treated surgically at the University ENT-Clinic Marburg. 115 cases (67,3%) showed a fracture of the orbital floor, either an isolated fracture of the orbital floor (24 cases) or combined with fractures of the orbital rim in combination with midfacial lesions of the central type (42 cases) or of the lateral type (49 cases). After analysing the mechanism of those fractures the main symptoms and the most important diagnostic investigations (x-ray tomograms, synoptometric investigations, forced-duction-test) are shown. By two examples the results of the prae- and postoperative synoptometric investigations are explained. Those investigations enable a more exact diagnosis in all types of orbital fractures and demonstrate exactly the postoperative functional results.

Diagnosis, Differential↗
PubMed1978

[Verrucous acanthosis (verrucous carcinoma) of the larynx (author's transl)].

Verrucous carcinomas are lesions occurring mainly in the buccal mucosa but sometimes they arise also in the larynx. The disease is characterized by a cornifying verrucous proliferation of the squamous epithelium, without atypias or metastases. The clinical and histological pictures of six observations are described and the differential diagnosis from hyperkeratotic papillomas and benign keratosis of the larynx are discussed. In one of these cases, 13 years after the beginning of the disease a focal cancerisation could be observed. The authors consider this disease not as a carcinoma and are not sure whether it is a true tumor at all. They propose therefore the name "verrucous acanthosis" instead of verrucous carcinoma and classify these lesions as facultative precanceroses.

Adult↗
PubMed1976

[Chronic laryngitis and carcinoma (author's transl)].

35 cases of continuous series of 841 laryngeal cancers were studied separately. Those patients had already been suffering from hoarseness for more than 2 years, in the average for 9 years. Many of these patients had been examined and treated by inhalations, and biopsies were taken because of a chronic laryngitis. Clinically in half of the cases a big carcinoma could be found. In 10 cases a chronic laryngitis had been diagnosed; in spite of the preceeding examination by microlaryngoscopy in 4 cases, however, the carcinoma could only be proved by histologic examination. The histologic examinations of the specimens regularly displayed an extended field of epidermisation of the laryngeal mucosa following chronic laryngitis, In these fields of epidermisation the carcinoma developed multicentrically and--in the early stages--mostly showed a covering-like, minutely infiltrating growth. Disseminated dot-like cancer-focuses in the epidermisation field and cancer buds arising from the basal layers of an intact covering of the hypertrophic epithelium could be observed several times. Chronic-hypertrophic laryngitis seems to favour the development of cancer within some patients (promoting factor), it even might accelerate it. As in about 6% of all the vocal cord cancers a preexistent chronic laryngitis is proved by history and clinical findings each patient with a chronic hypertrophic laryngitis must be examined by microlaryngoscopy as well as histological examinations and must be constantly observed.

Adult↗
PubMed1976

Late recurrence or radiation induced cancer of the larynx.

Twenty five patients with squamous carcinoma of the glottis (T1a and T1b) had undergone successful irradiation. Many years later they developed a so-called late recurrence. The following evidence shows that these 'late recurrences' are radiation induced: the interval of 5-18 years (mean 9.9 years) between the first and the second cancer correlates with the interval seen usually in radiation induced malignancy, recurrences generally appear during the first 2 years after irradiation, all the second cancers were found in the previously irradiated area, in patients treated by surgery only, late recurrences are extremely rare, histological examination clearly shows that the second carcinoma originates from the squamous epithelium and not from dormant nests in the deeper layers of the vocal cord. These factors should be taken into consideration when deciding between surgical or radiation therapy in younger patients with high life expectation.

Carcinoma in Situ↗
PubMed1976

[Secondary radiogenic cancer of the larynx (author's transl)].

Based on a series of 32 cases of late recurrence of early stage vocal cord cancer, the question of the pathogenesis of these lesions is discussed. Late recurrence, 5 to 18 years after treatment of the first tumour was observed in 3 cases after a laryngofissure procedure only and in 29 cases after laryngofissure combined with postoperative irradiation or after pure irradiation therapy. The clinical and statistical data and the histological picture of the second tumour show with a high degree of certainty that these second tumours are caused by the cancerogenic side-effect of the primary irradation, which destroyed the primary tumour. The danger that a patient, cured from his first cancer by irradiation, develops a second radiogenic cancer rises from year to year that the patient survives and certainly is much higher than had been suspected. Irradiation of a vocal cord cancer in a young patient with a relatively high life expectancy should no longer by used. Irradiated patients must be reviewed until the end of their lifes.

Adult↗
PubMedDate not supplied

Glomangioma of the nasal cavity. Case report and literature review.

A case of glomangioma of the nasal cavity and the literature concerning this rare tumor are reported. Differential diagnosis, symptoms, pathogenesis and therapy are discussed. This uncommon benign neoplasm is seldom located in the upper respiratory tract. It originates from proliferating arteriovenous capillary anastomoses. Intranasal glomus tumors produce nasal obstruction, epistaxis and sharp pain. The treatment of choice is complete excision of the tumor. The prognosis is excellent when the glomangioma is completely removed.

Adult↗