Biomedical subjects
Publications and source records attributed to H Gomes.
The value of a combination of ultrasound studies and barium swallow examination in the analysis of temporal relationships between apnea and reflux is demonstrated. The two techniques allow acute apneic spells induced by gastroesophageal reflux to be documented and underlying specific digestive tract disorders demonstrated. The high incidence of digestive tract disorders in this area has been identified.
Sonography appears highly sensitive in characterizing the severity of gastroesophageal reflux, screening the infants at risk of esophagitis. Sonography is also useful in evaluating efficacy of treatment. In our experience reflux is only damaging if constantly repeated and related to severe hiatal dysfunction. Ultrasound (US) is a good alternative for the assessment of hiatal function and gives furthermore indispensable morphological data.
Lissencephaly, a developmental malformation characterized by absence of sulci, may be suggested in dysmorphic or epileptic infants. Real time ultrasonographic findings correlated with typical electroencephalographic abnormalities establish the diagnosis.
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Two cases of telangiectatic osteosarcoma are described. The difficulty in differentiating this tumour from aneurysmal bone cyst is emphasized both from the pathological and radiological aspects.
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The authors report the case of a young white girl in whom the diagnosis of lymphoblastic leukaemia was made at the age of 5 years. Chemotherapy induced remission and long term surveillance began. Seven years after the onset of the first disease this girl died of an undiagnosed illness characterised by multiple nodules in both lungs. The autopsy gave the diagnosis of Kaposi's sarcoma.
The authors present the results obtained using a therapeutic combinaison of plasminogen-urokinase in vivo in 14 premature infants suffering from respiratory distress. 86 % survived, a considerable improvement over classical survival rates. In addition it appeared that the duration of oxygen therapy was shorter, secondary to limitation of extension of the disease.
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