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Biomedical subjects

H Gornig

Publications and source records attributed to H Gornig.

At least 19 recordsLinked to original sources

[Idiopathic hypereosinophilia syndrome].

The author describes a case of rare idiopathic hypereosinophilia demonstrated by a 26 years old man. General symptoms were founded 4 years before and now disease takes a progressive course including a rapid decrease of visual functions. Several alterations of organic findings were also found in heart, liver, lung, spleen and brain. A marked musculatur dystrophia in regions of upper arms and calf muscles was demonstrated by the young man. Using ophthalmoscope infarctions, edema and hemorrhage in the retina were found, also new growth of vessels, hemorrhage into the vitreous body and detachment of retina.

Eosinophilia↗

[Neuro-ophthalmologic findings following cerebral tumor excision in relation to topography and morphology].

The secured significance of position and extent of a cerebral tumour as well as its biological dignity with respect to the kind and frequency of the neuro-ophthalmological findings was the starting point of these investigations. In this retrospective study the findings of visual acuity, visual field and papillae of 204 patients operated on the cerebrum were determined and the significance of the morphological factors (position and size of the defect of the cerebral parenchyma, extent of the cerebral ventricles, degree of the cortical atrophy, influence of dignity) for the persisting ophthalmological deficiency phenomena was pointed out.

Adult↗

[Clinical, secretory and immunologic studies in Terrien disease].

The present paper begins with a description of the clinical picture of Terrien's disease. Using radionuclide dacryography (RND) to determine secretion, reduced tear secretion was found unilaterally in four patients and bilaterally in one (as indicated by the half-lives of the conjunctival drainage curves). In four patients RND failed to reveal any reduction in tear secretion on either side. The slightly elevated IgG values found in the tear fluid are in agreement with the clinically detected signs of inflammation. The serum parameters determined, such as iron, magnesium, and copper levels and the electrolyte, uric acid, and creatinine concentrations were normal.

Adult↗

[Neuropsychiatric-ophthalmologic and radiologic findings in sphenoid wing meningioma].

On the basis of 90 catamnestically pursued disease courses of surgically treated sphenoid bone wing meningioma of the years 1970 to 1987 the validity of the clinical-neuropsychiatric and neuro-ophthalmological examinations as well as the information value of the native X-ray pictures were ascertained. The aim of the work was to point out the possibility and necessity of an early clinical diagnosis by an intensified observation of the neuro-ophthalmological and neuro-psychiatric primary symptoms.

Epilepsy, Temporal Lobe↗

Early onset lymphoedema, recessive form--a new form of genetic lymphoedema syndrome.

We report on two brothers with chronic congenital lymphoedema. Besides the oedemas of limbs we found an unusual facial appearance, abnormalities of external genitals as a deformation sequence resulting from intrauterine oedemas and intestinal lymphoedema. This X-linked or autosomal recessive trait may be a new entity, to be differentiated from other genetic lymphoedema syndromes, the so-called familial protein-losing enteropathy, and dominantly inherited intestinal lymphangiectasia. A prominent sign of the syndrome is chemosis and injection of conjunctiva.

Child↗

[Eye symptoms in connatal lymphedema].

Two brothers with symptoms of connate ophthalmic lymphatic oedema are reported. The combination--connate generalized lymphatic oedema with antimongoloid eyelid, 'cow-eye phenomenon', euryblepharon and conjunctival lymphatic oedema of two brothers with healthy parents--suggests the existence of a new entity of this syndrome with recessive heredity.

Blepharoptosis↗

[Spontaneous changes in pigmentation in a conjunctival nevus].

The diagnosis and treatment of pigmented tumors of the conjunctiva require a great deal of experience. Some cases require particularly careful clinical supervision of the patient and possibly bioptic control. The differential diagnosis of melanocytic nevi and acquired melanosis is given with reference to an 8-year-old girl.

Child↗

[Pre- and postoperative eye findings in hypophyseal adenoma].

When hypophyseal tumours are present, eye symptoms are the leading signs; they indicate, however, an advanced tumour stage. On the basis of 274 histologically verified hypophyseal adenomas, pre- and postoperative ophthalmological findings were analysed. Disturbances of the visual acuity were found preoperatively in 85.4 per cent, scotomas in 86.1 per cent and an optical nerve atrophy in 67.2 per cent of the patients. After neurosurgical intervention, 41.8 per cent of the examined patients showed an improvement of the visual acuity and 59.2 per cent a regression of the scotomas. Optical nerve atrophy was found in 78.1 per cent which was a higher percentage than before the operation. Disturbances of the visual acuity or scotomas that have persisted for a prolonged period of time show, just as optical nerve atrophy, a more unfavourable prognosis. So it had to be the aim of a neurosurgical treatment to diagnose the pituitary adenoma at an early time in order to improve the chances of a success. Eosinophilic hypophyseal adenomas are more easily recognisable, because of acromegalia being present in almost all cases. Ophthalmologically, they show less scotomas since they reach the dimensions of the chromophobic or mixed type adenomas only rarely. When blindness has developed, the situation is very serious since only in exceptional cases a recovery of sight is possible.

Adenoma↗

[Evidence and meaning of monophasic potentials in the electromyogram of extraocular muscles of rabbits and cats (author's transl)].

The EMG of extraocular muscles of rabbits and cats was recorded by a concentric-needle electrode provided for clinical use. The EMG showed spike activity (at least biphasic, fast waves of 1 to 2 msec duration) and characteristic long-duration monophasic waves (decline for up to 7 msec). The monophasic potentials are interpreted as local depolarizations arising at the nerve-muscle junctions of multiply innervated muscle fibers. Spike- and monophasic potentials are discharged in independent rhythms whose frequency changes when the head position is altered. The frequency of spike- and monophasic potentials are changed in the same direction by labyrinthine reflexes. Spontaneous monophasic potentials recruit at a lower threshold.

Action Potentials↗

[Non-propagated potentials in the electromyogram of mammalian ocular muscles].

Electromyograms of mammalian extraocular muscles were recorded by means of a coaxial electrode. Besides normal extracellular spike potentials (1-2 msec duration), monophasic waves (with a decline lasting up to 7 msec) were recorded. As to the interpretation of these potential changes in terms of a potential drop that is produced by local currents flowing from the resting region of a fibre towards the active region consideration is given to two cases. First, a propagated active region (spike potentials, at least diphasic) and second, a stationary active region (with resulting monophasic waves). In the EMGs spontaneous monophasic potentials recruit at a lower threshold than spike potentials; frequency changes were observed when head position was altered. The latter are interpreted as local depolarizations occurring at neuromuscular junctions of multiple innervated muscle fibres among those fibre types that compose extraocular muscles.

Action Potentials↗