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H Gunschera

Publications and source records attributed to H Gunschera.

9 recordsLinked to original sources
PubMed1982

[The influence of chronic relapsing infections of the air passages on the subpopulations of peripheral blood lymphocytes in children with atopic diseases (author's transl)].

In 68 children with atopic diseases and 42 controls of the same age, the authors conducted lymphocyte differentiation examinations. The T-lymphocytes were determined by means of the E-rosette technique, whereas the B-cell counts were determined via monospecific fluorescein-marked anti-immunoglobulin sera. The entire group of juvenile atopics was separated into one group with massed infections and another group without susceptibility to infection. The group of children without susceptibility to infection concomitant with existing atopy, showed significantly relative T-lymphocyte counts, compared with the control group, the relative and absolute counts of the other lymphocyte subpopulation being normal. In the group of juvenile atopics with a pronounced tendency to infection, the T-cell deficiency and normal absolute T-lymphocyte counts are even more conspicuous, whereas the B-cell and O-cell counts are higher than with the control group. It is possible to identify the influence of chronic relapsing infections on the lymphocyte subpopulation in atopics. The article discusses the problem of the type of cellular immunodefect in atopic children without previous history of an infection.

Adolescent↗
PubMed1982

[The HbA1c-determination with the aid of isoelectrofocusing method in the out patient control of juvenile diabetics (author's transl)].

In juvenile diabetics treated on an outpatient basis, the HbA1c value was determined by means of isoelectric focusing. This method proved to be relatively simple and reproducible. Approximately 24 samples can be examined simultaneously after capillary withdrawal. The following correlations were found: 1. with the average urinary glucose excretion - a) measured by the clinitest method, measurement being effected several times daily over a period of 4 weeks (R = 0.5063), as well as b) with the 24-hour urinary glucose excretion of the day of withdrawal, 4 weeks, 8 weeks and 12 weeks previously. Best agreement was found between the HbA1c value and the sum of urinary glucose excretion on the day of withdrawal, 4 weeks and 8 weeks previously (correlation coefficient R = 0.6022). 2. a relationship was also found in the current blood sugar levels (correlation coefficient R = 0.5061). The results are discussed with regard to the significance of the HbA1c measurement.

Adolescent↗
PubMedDate not supplied

[Is there a relation between an increase in IgM in the newborn infant and the course of pregnancy and labor?].

In order to check the significance of the serum IgM concentration in newborns the IgM levels in the placental blood of 263 randomly selected neonates were determined; in 105 of these children the IgM concentration was again determined on the 6th day of life. The maternal IgM concentrations were also determined for the purpose of comparison. All of the newborns were allocated to infection risk categories on the basis of history and clinical data. The findings were evaluated on the basis of the mean values with simple standard deviation, single-case analysis and arrangement of the medium values in sequence. Significantly elevated IgM concentrations were found in newborns with the risk factor asphyxia on the 6th day of life. There was a certain tendency to elevated IgM concentrations - established on the basis of the mean values and the median value grouping - in the groups with maternal infection, premature rupture, frequent vaginal examination, and post-term birth of the child. The investigation shows that the majority of elevated IgM concentrations in neonates in whom no infection can be found are not closely correlated to a certain risk factor. An elevated IgM concentration in a newborn appears to be a factor of low specificity with regard to infection. However, in the diagnosis of neonatal infections it provides additional information in the overall context of the clinical examination.

Asphyxia Neonatorum↗