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Biomedical subjects

H H Ehricke

Publications and source records attributed to H H Ehricke.

7 recordsLinked to original sources

SONOSim3D: a multimedia system for sonography simulation and education with an extensible case database.

This paper addresses the problem of sonography education and training. A method and software package for ultrasound simulation are presented. The latter is based on standard PC technology and allows graphical interaction with a virtual patient and transducer. The most essential component is an extensible case database with various cases from different clinical disciplines. A case consists mainly of a 3D image dataset, sonographically acquired from a patient or a healthy subject. It represents an anatomical region which may be investigated. Furthermore, a method for the geometric registration of the data volume of a new case with the model of the virtual patient is described. This enables the arbitrary extension of the case database.

Computer Simulation↗

Correction of spatial distortion in magnetic resonance angiography for radiosurgical treatment planning of cerebral arteriovenous malformations.

A treatment planning system based on magnetic resonance (MR) angiographic imaging data for the radiosurgery of inoperable cerebral arteriovenous malformations is reported. MR angiography was performed using a three-dimensional (3D) velocity-compensated fast imaging with steady-state precession (FISP) sequence. Depending on the individual MR system, inhomogeneities and nonlinearities induced by eddy currents during the pulse sequence can distort the images and produce spurious displacements of the stereotactic coordinates in both the x-y plane and the z axis. If necessary, these errors in position can be assessed by means of two phantoms placed within the stereotactic guidance system--a "2D-phantom" displaying "pincushion" distortion in the image, and a "3D-phantom" displaying displacement, warp, and tilt of the image plane itself. The pincushion distortion can be "corrected" (reducing displacements from 2-3 mm to 1 mm) by calculations based on modeling the distortion as a fourth order 2D polynomial. Displacement, warp, and tilt of the image plane may be corrected by adjustment of the gradient shimming currents. After correction, the accuracy of the geometric information is limited only by the pixel resolution of the image (= 1 mm). Precise definition of the target volume could be performed by the therapist either directly in the MR images or in calculated projection MR angiograms obtained by a maximum intensity projection algorithm. MR angiography provides a sensitive, noninvasive 3D method for defining target volume and critical structures, and for calculating precise dose distributions for radiosurgery of cerebral arteriovenous malformations.

Humans↗

Imaging and graphics in medicine: concept of an object-oriented platform for clinical research.

We present a workstation-based research platform with two major components. A turnkey application system provides a functionality kernel for a broad community of clinical users with an interest in digital imaging. A development toolbox allows efficient implementation of research ideas and consistent integration of new applications with the common framework of the turnkey system. The platform is based on an elaborate object class structure describing objects for image processing, computer graphics, study handling and user interface control. Thus expertise of computer scientists familiar with this application domain is brought into the hospital and can be readily used by clinical researchers.

Computer Graphics↗

MRA-guided stereotactic radiation treatment planning for cerebral angiomas.

Stereotactic neurosurgical interventions are characterized by a high risk of rupturing intracranial vessels or damaging vital brain structures. By MRI and MRA, the anatomic information necessary for stereotactic treatment planning may be assessed with a single modality as a high-resolution digital image volume. The adequacy of MR as a modality for stereotactic guidance is demonstrated by the example of the radiosurgical treatment of cerebral angiomas. An optimized acquisition protocol, a stereotactic apparatus, a distortion correction and minimization method, and a 3D treatment planning workstation are elements of a proposed preoperative approach which in a clinical study met with good acceptance.

Algorithms↗

Medical workstations for applied imaging and graphics research.

We present a medical workstation for the efficient implementation of research ideas related to image processing and computer graphics. Based on standard hardware platforms the software system encompasses two major components: A turnkey application system provides a functionally kernel for a broad community of clinical users working with digital imaging devices, including methods of noise suppression, interactive and automatic segmentation, 3D surface reconstruction and multi-modal registration. A development toolbox allows new algorithms and applications to be efficiently implemented and consistently integrated with the common framework of the turnkey system. The platform is based on an elaborate object class structure describing objects for image processing, computer graphics, study handling and user interface control. Thus expertise of computer scientists familiar with this application domain is brought into the hospital and can be readily used by clinical researchers.

Algorithms↗

Integrated 3D display of brain anatomy and intracranial vasculature in MR imaging.

In many clinical situations neuroradiologists and neurosurgeons are keenly interested in images displaying both brain structures and intracranial vessels in an integrative manner. In this paper an approach to three-dimensional visualization of brain and vascular structures from magnetic resonance (MR) volume data is reported. It has been designed with the aim of providing a robust and reliable image processing tool for routine clinical applications. The method has been made possible by recent developments in MR image acquisition, especially MR angiography and rapid gradient-echo sequences (Turbo-fast low angle shot). On the basis of the ray-tracing principle, integration of brain and vessel anatomy into a single 3D image is achieved. Image data are acquired with flow-compensated gradient-echo pulse sequences. Even slow flow in venous structures may be demonstrated using a two-dimensional sequential-slice scanning method. Finally, if incorporated into an interactive image processing system, this technique may be used as a planning tool allowing a surgical "rehearsal" prior to actual operative exposure and resection of a lesion.

Brain↗

Use of MR angiography for stereotactic planning.

With the introduction of MR angiography (MRA) into clinical routine MR protocols, it has become possible now to image flowing as well as stationary tissue with excellent contrast using a single modality. This has opened up new perspectives for planning stereotactic approaches, which are characterized by high risks for damaging intracerebral vessels or vital brain structures. In this article we present an MRA based planning method for the treatment of arteriovenous malformations by stereotactic radiosurgery. It includes flow compensated gradient echo pulse sequences for the acquisition of angiographic MR datasets, a stereotactic MR marker system, an algorithm for the correction of geometric distortion of MR image data, and a three-dimensional workstation system for the creation and evaluation of treatment plans. The latter is based on the concept of simultaneously displaying both MR slice and angiographic projection images. This allows the evaluation of intracerebral vasculature together with brain anatomy. The MRA guided planning approach was tested and compared to a conventional X-ray angiographic technique in a clinical study. Our satisfactory results suggest that MRA is a technique that can be used advantageously for stereotactic planning.

Brain↗