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Biomedical subjects

H H Horch

Publications and source records attributed to H H Horch.

At least 55 records · Page 3Linked to original sources
PubMed1992

[Initial clinical experiences with the photodynamic therapy (PDT) of oral cavity carcinomas].

Photodynamic therapy (PDT) is based on the selective accumulation of photosensitizing agents in tumor tissues. Activation of the photosensitizer with ligh of suitable wavelength leads to tumor destruction preserving healthy tissues. 13 carcinomas stage T1 and T2 of the oral cavity in men were treated. Necroses of a depth from 1.5 to 6 mm occurred regularly. Therefore photodynamic therapy seems to be suitable to treat small, superficial cancers of the oral cavity, especially, if the tumors are multilocated.

Carcinoma↗
PubMed1986

CO2 laser surgery of oral premalignant lesions.

Experiences gained in the CO2 laser treatment of patients with oral dysplastic precancerous lesions are presented. Besides 7 lichens planus, 50 leukoplakias of all grades of dysplasia, and carcinoma in situ and one lentigo maligna were removed superficially with a defocused laser. Within the average follow-up period of 37 months, 22% local recurrences were observed. In comparison with conservative drug therapy, conventional surgical procedures, and cryosurgical therapy, the CO2 laser treatment of multicentric premalignant diseases of the oral mucosa can be recommended as an alternative therapy.

Carbon Dioxide↗
PubMed1984

[The role of radiotherapy in the treatment of granuloma gangraenescens (lethal midline granuloma].

The granuloma gangraenescens in the oral, maxillary and facial region is a rare disease. It is a destroying process in the region of palate, nose, paranasal sinuses, cheeks and orbit with characteristic signs of granulomatosis, infection and malignancy. The disease shows often a lethal development with cachexia or sepsis. Besides local inflammations and tumors, the granulomatosis of Wegener, and the so-called necrotizing sialometaplasia are above all to be excluded by differential diagnosis. Five cases are presented in order to describe the diagnostic and therapeutic problems. In literature, the greatest efficacy is attributed to radiotherapy, however, a detailed definition of the most efficient irradiation conditions cannot be given yet because of the small number of cases. Good long-term results or recoveries can be achieved in 75 to 80% of cases by a relatively high radiation dose of 40 to 50 Gy administered within four to five weeks. During the observation time of two to six years, no one of the five patients treated here only by megavoltage therapy showed a recurrence.

Adult↗
PubMed1982

The use and evaluation of CO2 laser in cleft palate surgery.

Experimental studies with Rhesus monkeys showed that lateral relaxation sutures used for the reconstruction of the cleft palate can be set without any loss of blood and that epithelialization is almost complete 10 days after the operation. Clinical measurements of blood loss showed a mean blood loss of 13.4% for 30 conventionally operated cleft palates and 8.6% for 10 operated with a CO2 laser. With partial use of the laser, this corresponds to a reduction in the operation-related blood loss of 36%. The findings show that routine use of the CO2 laser for reconstruction of a cleft palate can currently be recommended for paramarginal relaxation sutures in bridge and pedicled flap methods, thereby reducing the blood loss considerably below the mean shock threshold of 10%.

Blood Transfusion↗