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Biomedical subjects

H H Jend

Publications and source records attributed to H H Jend.

At least 19 recordsLinked to original sources

Microangiopathic hemolytic anemia (MAHA) as paraneoplastic syndrome in metastasized signet ring cell carcinomas: case reports and review of the literature.

We report on two spontaneous cases of microangiopathic hemolytic anemia (MAHA) as first manifestation due to metastasized signet ring carcinoma, one of gastric and one of unknown origin. The patients presented with an acute onset of Coombs negative hemolytic anemia and fragmentocytes in the peripheral blood smear which are typical for MAHA. These case reports present MAHA as a rare paraneoplastic syndrome in patients with metastasized signet ring carcinoma. Parallel to symptomatic treatment we started chemotherapy treatment (ELF and PLF regimen, respectively). In both cases we were able to control the MAHA and cancer progression.

Anemia, Hemolytic↗

[Differential diagnosis of morbus Crohn disease: intussusception of the colon].

We report on a 35-year old women with severe abdominal pain, cramps, diarrhea with blood and a palpable paraumbilical resistance. The symptoms appeared a few days before admission and were recurrent within the last two years. The abdominal ultrasound showed a target sign with a thickened wall from the right to the left colon flexure with inhomogeneous reflexes. The CT-scan and barium enema showed an intussusception of the colon. After hemicolectomy of the right colon a 6 x 4 x 4 cm exophytic tumor near the ileocoecal valve was detected. Histologically the tumor was diagnosed as adenocarcinoma of the coecum (pT2pNOpMX G2).

Adenocarcinoma↗

[The value of conventional skull x-rays after head injuries].

A retrospective study was used in an attempt to clarify whether skull fractures or clinical findings can be used for diagnosing intracranial injuries and which clinical features indicate that skull X-rays are unnecessary. 78 patients (1.5%) had a skull fracture and 41 patients (0.8%) had suffered intracranial injuries. Of 57 patients with skull fractures, 40% (23) showed evidence of intracranial injury and 60% (34) did not. Amongst 41 patients with intracranial injuries, 44% (18) failed to show a skull fracture. Patients with a skull fracture (without intracranial injury) showed just as many symptoms as patients without skull fracture. Patients with intracranial injuries most commonly showed neurological deficits, unconsciousness, or required intubation. Any one of these criteria or a combination of these indicated the presence of intracranial injury with a high degree of probability. These criteria permit economy with skull X-rays and indicate when to use other diagnostic means (CT). For this the patient should be mentally quite normal. There should be a definite history and a reliable observation period of 24 hours.

Adolescent↗

[Use of high-resolution algorithms and thick sections in computerized tomography staging of bronchial carcinoma].

The purpose was to determine whether 8 mm slice sections with high resolution algorithms would prove superior to standard methods for the CT staging of bronchial carcinomas. The raw data from CT examinations in 50 patients using standard methods and the high resolution method was calculated, documented and compared. Within the lung parenchyma, small foci or metastases, peritumorous infiltrates, bronchial narrowing, bronchial outlines, vessels and areas of poor aeration were significantly clearer. Pleural thickening and subpleural fat stripes were also better seen. Abnormalities in the mediastinum were equally well shown. High resolution algorithms with 8 mm slice sections are recommended for routine staging of bronchial carcinomas, particularly if the calculations can be done quickly, as is possible on modern apparatus, without increasing the duration of the examination.

Algorithms↗

[The assessment of stability in spinal fractures].

The assessment of stability is one of the most important problems in the analysis of vertebral trauma. There are numerous indirect signs of instability. The "three column model" provides a concept towards a better understanding of instability. Compared with the conventional complex classifications, the new system based on the "three column model" provides certain advantages.

Fractures, Bone↗

[An intrapulmonary hematoma induced by a Swan-Ganz catheter].

A case of circumscribed intrapulmonary haematoma induced by a balloon-tipped catheter is presented in a 56 year old patient with coronary heart disease. The bleeding site appeared as a pulmonary circular focus or coin-shaped lesion on the chest radiograph. The authors discuss possible causes and risk factors of intrapulmonary haematomas and differential diagnosis of pulmonary coin-shaped lesions.

Catheterization, Swan-Ganz↗

[Bedside pictures and thorax-CT of intensive care patients].

Computed tomography is a rare radiologic procedure in the intensive-care patient. This is due to the complicated procedure involved. Although x-ray film imaging in the supine patient has definitely improved in quality, computed tomography will continue to be used as the decisive method in cases that cannot be clarified completely, i.e. complex lesions, drainage, in the first examination of a polytraumatic patient, in the search for empyemas and abscesses, and in the clarification and identification of mediastinal processes.

Critical Care↗

[High-resolution MRT with increased magnetic field gradients and a 512(2)-data matrix: initial clinical experiences].

By increasing the strength of the magnetic field gradients of a whole-body imager to 9.4mT/m, it was possible to obtain spin-echo images with short echo delays and high spatial resolution. The reduction of the pixel size was effected either by decreasing the field of view or by increasing the scan matrix (512(2) pixel). To prevent loss of signal-to-noise ratio, the scan parameters had to be carefully selected. With the 512(2) matrix, the resolution could be increased without decreasing the field of view, so that backfolding artifacts were avoided. In comparison with the 256(2) matrix, the 256 x 512 matrix provided improved resolution in the frequency encoded direction without an increase in acquisition time.

Humans↗

[Dacryocystography--conventional technic or digital subtraction technic?].

The lacrimal drainage systems of 92 patients were examined by a digital subtraction technique; 30 patients were examined additionally by a conventional technique, using films obtained during screening for the contrast injection. The digital subtraction dacryocystogram provided excellent demonstration of the lacrymal sac and of the tear ducts, but there is little diagnostic gain when compared with the conventional technique. Both methods are highly reliable. In view of its low radiation dose and rapid and simple course, conventional dacryocystography is regarded as the method of choice for routine examinations. The digital subtraction technique should be reserved for special problems.

Adolescent↗

Semiquantitative SPECT imaging for assessment of bone reactions in internal derangements of the temporomandibular joint.

The temporomandibular joints (TMJs) of 60 patients with arthrographically confirmed internal derangements and 30 volunteers were examined with single photon emission computed tomography (SPECT). Semiquantitative evaluation was done by forming a quotient from the counts of a constantly sized TMJ-ROI relative to the overall counts of the cranium. The TMJ/cranium quotient depended on the age of the subject, with younger patients showing a larger quotient than older ones. Normal joints were separated from the afflicted ones by means of a discriminant analysis. Sensitivity of semiquantitative evaluation was 78% (disc displacements with reduction) and 89% (disc displacements without reduction). Correct visual evaluation was made in 53% of the reducing and 75% of the nonreducing discs. Semiquantitative SPECT of the TMJs provides important information on the extent of osseous changes in afflicted joints and is suitable for follow-up of splint therapy. It may also be helpful as a screening method in detecting clinically normal joints before arthrography is carried out and in assessing the presumptive response to treatment with a splint.

Adolescent↗

Significance of arthrography and computed tomography in the assessment of internal derangement of the temporomandibular joint.

Arthrography was performed on 56 joints of 47 patients presenting with symptoms of pain and dysfunction of the temporomandibular joint. The diagnosis could be confirmed in 53 joints. In addition, there was evidence of 13 perforations and 7 joints with adhesions. In 51 of the affected joints, computed tomography (CT) was also performed to compare both methods. The same CT procedure was performed on 12 joints of patients without any joint problem. Almost consistently (88%), an arthrographically anteriorly dislocated disc was detectable in the axial CT scans. 92% of the healthy joints showed normal soft tissue structures. For CT visualization of a displaced disc sagittal reformations or primary sagittal scans are not necessary. Confirmation of possible perforations or adhesions cannot be made by CT. Comparing the advantages and disadvantages, arthrography must still be regarded as superior to CT. In some cases, however, CT is a valuable tool in assessing an internal derangement.

Arthrography↗

[Semiquantitative SPECT of anterior dislocation of the temporomandibular joint disk].

SPECT examination of the TMJ using 99m Tc-MDP was performed in 43 patients with arthrographically proven anterior dislocation of the disc and in 30 normals. The results were evaluated visually and also in a semi-quantitative manner that took account of relative 99m Tc activity in the TMJ and of the age of the patient. In the presence of arthrographically proven anterior, but reversible, disc dislocation, the semi-quantitative method proved positive in 75% of cases (28 cases). In joints with fixed anterior dislocation (29 cases), bone changes were demonstrated in 86%. Visual evaluation was positive in 50% of reversible, and in 72% of non-reversible dislocations. Semi-quantitative SPECT of the TMJ is excellent for demonstrating bone reaction resulting from TMJ dysfunction and for indicating the severity of the joint abnormality.

Adolescent↗

[Computed tomography of anterior dislocation of the temporomandibular articular disk].

In a prospective study, the findings on arthrography and CT in 51 TMJs with anterior meniscus dislocation were compared. The CT diagnosis of anterior dislocation was made by a standardised method which we have developed and which depends upon evaluating axial sections. Sensitivity of the CT methods was 87%. In the absence of arthrography, a negative diagnosis in the asymptomatic contralateral side was made in 81%. Ruptures and adhesions could not be demonstrated by CT. For these reasons, arthrography is to be preferred to CT for making the initial diagnosis. CT should be carried out for special indications, such as contrast sensitivity, the documentation of a clinically confirmed diagnosis and for follow-up of treatment. Currently an attempt is being made to stage the disease by computed tomography.

Arthrography↗

[Results and experiences with digital subtraction angiography (DSA) in traumatic vascular lesions of the thoracic aorta and the supra-aortic branches].

Numerous positive reports on the results obtained with digital subtraction angiography (DSA) in x-ray diagnostics in the visualisation of peripheral vascular areas, have been published ever since that method was introduced. From a surgical point of view it has therefore been suggested to extend the indication for vascular visualisation on account of the low invasiveness of venous DSA (vDSA). Only few reports have been published on the suitability of vDSA in traumatic vascular lesions. Whereas Starck and Rauber recommend vDS as a feasible method for the visualisation of traumatic vascular lesions, Galanski and Fiedler continue to postulate the need for arterial DSA (aDSA) in the clarification of degenerative diseases of the supraaortal branches. Conventional angiography has lost some of its importance in traumatic vascular lesions, as Traupe has stated. Our first experiences with vDSA in traumatic vascular lesions have been partly unsatisfactory. This, and the resulting consequences, are described in the present article.

Aorta, Thoracic↗

[Analysis of the axis in patients with patellar dislocation].

The authors investigated in 25 patients with luxations of the patella if an increased incidence of defective torsions of the leg skeleton could be demonstrated. The torsion conditions of the lower extremity can be easily shown by computed tomography. This was confirmed when 32 femur preparation and 95 sound extremities were examined. The comparison of measuring results does not show any difference between patients and control group regarding the torsion of tibia and femur and the position of the tuberosity of the tibia. Patients with luxations of the patella show an increased external rotation of the tibia with respect to the femur due to a lack of medial muscular and ligamentary guide.

Femur↗