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Biomedical subjects

H H Kaye

Publications and source records attributed to H H Kaye.

8 recordsLinked to original sources
PubMed1977

Vater syndrome: hypothesis and report of two further cases.

Two cases are reported of the association of a group of abnormalities defined as the Vater syndrome, together with a hypothesis, based on the presence of normal cell death during embryogenesis, on how they occur together so frequently. Although the mechanism of normal cell death is unknown, adjacent cells are probably affected sublethally and subsequently recover. A teratogenic situation introduced simultaneously with the occurrence of normal cell death may further diminish the viability of those adjacent cells, causing increase in the necrotic zone and loss of both normal tissue and growth potential.

Abnormalities, Multiple↗
PubMed1975

Ejection phase indices of left ventricular performance in infants, children, and adults.

A validatory study of quantitative single plane left ventricular cineangiography is presented, using human left ventricular casts ranging in size from 1.6 to 135 ml. Good correlation was found between actual and calculated volumes (r=0.967). 62 patient studies were carried out and the value of the usually calculated indices of left ventricular performance were compared to one another. Ejection fraction and mean rate of circumferential fibre shortening (mean Vcf) were found to be the best discriminators of abnormal left ventricular function, and, on the basis of the presented data, it is suggested that mean Vcf is the more sensitive index of left ventricular performance.

Adolescent↗
PubMed1975

Studies in a newborn infant with supraventricular tachycardia and Wolff-Parkinson-White syndrome.

A neonatal patient with Wolff-Parkinson-White type A and supraventricular tachycardia is described. Demonstration of the mechanism of the tachycardia and its termination were achieved using intracardiac electrography and cardiac pacing. Quantitative left ventricular angiography and echocardiography showed impaired left ventricular function following the arrhythmia. Serial echocardiograms demonstrated the subsequent return to normal left ventricular performance.

Angiocardiography↗
PubMed1975

Validity of echocardiographic estimates of left ventricular size and performance in infants and children.

Echocardiography has been shown to be a reliable method for estimating left ventricular size and function in adults, but little attention has been paid to its application to infants and children. This paper describes a validatory study in 40 children aged between 4 days and 16 years. There was a significant correlation between angiocardiographic and echocardiographic estimates of left ventricular end-diastolic volume (r=0.76), left ventricular end-systolic volume (r=0.68), and ejection fraction (r=0.73). Left ventricular mean circumferential shortening rate (mean Vcf), however, gave the mostsignificant correlation (r=0.91). These findings indicate that while care must be exercised in interpreting indices of left ventricular size and performance derived from echocardiography, these measurements, and in particular mean Vcf, do offer a useful and reliable means of assessing left ventricular function in infants and children.

Adolescent↗