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Biomedical subjects

H H Lin

Publications and source records attributed to H H Lin.

At least 199 records · Page 11Linked to original sources
PubMed1987

Transplacental leakage of HBeAg-positive maternal blood as the most likely route in causing intrauterine infection with hepatitis B virus.

Thirty-two HBeAg-positive carrier mothers and their 32 babies were investigated to elucidate the mechanism involved in intrauterine infection with HBV. Five mothers had symptoms and signs of threatened abortion and/or threatened preterm labor. Three mothers gave birth more than 6 weeks after the episodes, and their babies were those infected in utero. The other two gave birth within 1 week after the episodes, and the two babies were treated with HBIG immediately after birth; HBV infection was successfully prevented. Therefore we suggest that transplacental leakage of HBeAg-positive maternal blood, which is induced by uterine contractions during pregnancy and the disruption of placental barriers, is the most likely route to cause HBV intrauterine infection.

Carrier State↗
PubMed1987

A hormone-producing thecoma of broad ligament.

A very rare extraovarian hormone-producing thecoma, originated from the broad ligament, is described. Its preoperative diagnostic difficulty, clinical significance, differential diagnosis and histogenesis are discussed.

Adnexa Uteri↗
PubMed1987

Hepatitis delta virus infection in Taiwan.

In Taiwan the prevalence of anti-Delta was low among asymptomatic HBsAg carriers, patients with HCC and acute type B hepatitis, intermediate in HBsAg carriers on hemodialysis, patients with chronic type B hepatitis and liver cirrhosis, particularly HBeAg negative ones, and very high in intravenous drug abusers. It is important to prevent the spread of HDV infection in this hyperendemic area of HBV.

Carrier State↗
PubMed1986

[Histopathological changes in endometrial cancer treated with tamoxifen].

Eight cases of endometrial adenocarcinoma, including 7 well differentiated cases (stage Ia three, stage Ib three, stage II one) and I poorly differentiated case (stage IVb), were treated with Tamoxifen (20 mg/day) for 7-14 days. The average age of these patients was 59.1 +/- 10.9 years old and they were all postmenopausal for between 6 months and 30 years. The endometrial tissue was biopsied before Tamoxifen administration and half of it was investigated for progestin receptor (PR) and estrogen receptor (ER) while the remainder was used for histopathological examination. After surgical treatment, some tissue fragments of the endometrium were taken for investigation of PR and ER. The effect of Tamoxifen was then studied for the amount of PR, ER and histopathology. The result was that the amount of PR was increased in well differentiated cases whereas it was unchanged in poorly differentiated ones, and the amount of ER was decreased in all cases. Meanwhile, obvious histopathological changes were noted as follows decrease of glandular epithelial stratification, increased secretory activity, increased epithelial cell size with columnar cell type, increase of transparent, vacuolated cytoplasm, increase of nuclear size with variable shape and prominent nucleoli with marginal aggregation of chromatin. However, no stromal change was noted. Furthermore, the greater the increase in the amount of PR, the more conspicuous histopathological change was noted. It was concluded that Tamoxifen could produce both functional (PR, ER) and morphological (histopathology) changes in endometrial cancers.

Adenocarcinoma↗
PubMed1985

Studies on the risk factors of intrauterine infection of hepatitis B virus.

In order to elucidate the mechanism involved in HBV intrauterine infection, some risk factors were checked among 22 HBsAg and HBeAg positive carrier mothers. It was found that the HBV intrauterine infection had no correlation with (1) abnormal maternal liver functions, (2) high HBsAg and HBeAg titers or high concentration of HBV-DNA in the maternal serum or (3) HBeAg titer in the cord serum. Four babies were born to mothers with positive symptoms and signs of threatened abortion and/or threatened premature labor during pregnancy. Among them, two babies born at full term were HBV infected cases in utero, whereas the other two babies born within one week after the occurrence of threatened premature labor showed negative HBsAg antigenemia at birth and HBIG was immediately administered and prevented HBV infection. We therefore inferred that placental leakage caused by uterine contraction during pregnancy could cause maternal blood to enter the fetal circulation and cause HBV intrauterine infection. Moreover, even if placental leakage occurs, HBV infection might be prevented by administering HBIG within a week.

Female↗
PubMed1977

Activation analysis of mercury in urine samples of electrolysis cell workers.

The activation method of determination of trace amounts of Hg in human urine has been studied by introducing a simple amalgam deposition method. Human urine samples were obtained from the alkali chloride, electrolysis plant equipped with Hg cells. The capacity of Cu powder for Hg quantity, the pH conditions, and the shaking time were described. The results showed that the Hg contents in workers' urine samples varied from 33 ppb to 60 ppb depending on working conditions.

Activation Analysis↗
PubMedDate not supplied

Hepatic parenchymal calcifications--differentiation from intrahepatic stones.

Intrahepatic hyperechoic lesions with acoustic shadows could be stones or nonspecific calcifications. To verify this, 9 patients with hepatic parenchymal calcifications were compared with 40 patients with intrahepatic stones. A set of criteria are proposed for the diagnosis of intrahepatic stones: (A) dilated intrahepatic duct; (B) pneumobilia; or (C) 2 or more of the following: (1) common hepatic duct more than 6 mm in diameter, (2) multiple lesions in one lobe, (3) left lobe involvement, and (4) elevated serum alkaline phosphatase. The sensitivity, specificity, and overall accuracy were 97.5%, 88.9%, and 95.9, respectively. The criteria help in the selection of patients for evaluation of intrahepatic stones.

Bile Duct Diseases↗