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Biomedical subjects

H H Matthiass

Publications and source records attributed to H H Matthiass.

At least 19 recordsLinked to original sources

Histopathological features of unilateral stapling in animal experiments.

Blount stapling of the proximal medial tibial growth was performed in 10-week-old domestic pigs. A total of 37 animals for up to 17 weeks were followed up. The histological evaluation showed a different reaction of the growth plate in the medial (stapled), central and lateral area. Up to 6 days after stapling the morphological features were characterized by deviations of the cell column from the axial alignment. Herniations of mature chondrocytes as well as isles of epiphyseal cartilage splintered into the adjacent metaphyseal cancellous bone were seen. From the 10th to the 11th postoperative day on there was a decline in the number of distal hypertrophic and degenerating cartilage cells due to impaired proliferation. Cell atrophy due to disturbed maturation or cell degeneration was evident. Local clusters of chondrocytes with loss of columnar arrangement indicated impaired chondrogenesis. Twenty-eight days after the operation coarser structures and changed alignment of cancellous bone characterized the morphological picture. The postoperative follow-up showed epiphyseal plates bounded by mature bone blocks or even a distinct sheet of horizontally oriented bone plates on the metaphyseal side. Many metaphyseal findings, such as augmented hypertrophic cells in the early postoperative period, or platelike limitations of the epiphyseal plate complete the morphological picture.

Animals

Metaphyseal aspects of stapling. An experimental study in pigs.

Blount stapling of the growth plate induced changes in the metaphyseal architecture, which progressed in correlation to the postoperative follow-up. The stereological investigations revealed a subtile reaction of the medial stapled tibial plate in a total of 37 domestic pigs (10 weeks old) during the postoperative follow-up (up to 17 weeks). Zone 1, 380-1120 microns distal to the plate representing "bone modelling", and zone 2, 1180-2360 microns distally representing "bone remodelling", were investigated separately. The findings in zone 2 were very similar to zone 1 but were less extensive. The parameter most sensitive to stapling was the surface density; the trabecular distance showed parallel but less impressive findings. The specific surface and trabecular diameter changed with some delay. The last parameter to change was the volume density.

Animals

Two-stage therapy in the treatment of sacral tumors.

Sacral tumors are rare and may be clinically overlooked for a long period, because the symptoms and signs are often mild and non-specific. This led to frequent errors in clinical diagnosis and a long delay between the onset of symptoms and treatment. On presentation the lesions frequently expanded the anterior cortex, however, in most patients the periosteum of the sacrum and the presacral fascia form an unbroken barrier for a tumor. The pelvic viscera are not infiltrated by the tumor until late. Wide excision is difficult and often causes urogenital and/or anorectal dysfunction, but preserving the sacral nerve roots often leads to local recurrence. Surgical wide excision with a combined anterior-posterior approach is considered the treatment of choice for large lesions with significant anterior intrapelvic extension. This paper reports data resulting from the treatment of five large sacral tumors with comments on the results.

Adult

The surgical reduction of spondylolisthesis.

The Schnöllner operation for reduction of spondylolisthesis was performed through a transversal incision. After removal of the disc, two pedunculus screws with two different threads are inserted. Over these screws the reduction is performed against a slotted sacral plate. The operations were performed at the following levels: 48 at L5-S1, seven at L4-L5, and two at both levels. 70.8% of the patients had preoperative lumboischialgia, 23.3% lumbalgia. Postoperatively, 92.1% were without pain. Twenty-seven patients had preoperative sensory disturbances, while only five had such disorders five years after operation. New sensory disturbances occurred after operation in 11 patients, seven of these persisted. Before operation, 27 patients had pareses of the foot and toe extensors; after operation, ten of them. Paresis occurred in 12 cases, of which three persisted. In 13 cases the reposition was complete, in 17 cases the displacement after operation ranged from 11% to 30%. The lumbosacral angle was markedly diminished.

Adolescent

[Rehabilitation of the elderly person].

Orthopaedic treatment for the elderly is aimed at enabling these persons to master their life. It includes not only the actual treatment of illness or disability, but also the influence exerted by their environment. Among the main problems aging people encounter in coping with orthopaedic disorders are decreasing adaptability and limitations in their capability to cope with stress situations. Not only the bone itself, but also the motoricity are affected. Physical therapists and physicians must take these factors into account in their efforts to successfully assist these aging people.

Aged

Sex-linked chondrodysplasia punctata?

Widespread atrophic lesions and pigmentary disturbances of the skin distributed in a linear or whorled pattern, are seen in some patients with chondrodysplasia punctata of the Conradi-Hünermann type. Arguments are presented in favor of the hypothesis that this association of anomalies constitutes a distinct genetic disorder, which is inherited as an X-linked dominant trait lethal in hemizygous males.

Adolescent

Surgical treatment of solitary bone cysts.

A special method of subperiosteal segmental resection is described as an operative treatment for solitary bone cysts in long bones. This procedure exploits the high osteogenetic potency of the periosteum in adolescence. An autogenous or homologous fibula bone graft locked between the ends of the cyst serves to maintain the length of the bone fragments and acts as a guiding rod for continued subperiosteal new bone formation. There is full reconstruction of bone stability and function at both the cyst region and the donor region (fibula).

Adolescent