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Biomedical subjects

H H Seedorff

Publications and source records attributed to H H Seedorff.

18 recordsLinked to original sources

Plaques causing hemianopsia or quadrantanopsia in multiple sclerosis identified by MRI and VEP.

Four patients with definite multiple sclerosis (MS) gave evidence of demyelinating plaques that produced a form of visual loss atypical of MS, i.e. homonymous quadrantanopsia (women, 22 and 30 years), and homonymous hemianopsia (men, 30 and 42 years). Cerebral magnetic resonance imaging (MRI) identified areas with increased signal intensity situated corresponding to the observed visual field defects. The results of visual evoked potentials (VEP) were in accordance with what should be expected from anatomical considerations.

Adult↗

Ophthalmologic prognosis in benign intracranial hypertension.

In a prospective study twenty patients with benign intracranial hypertension, 15 females and five males with mean age 34 years (range 12-61 years), were followed up from 12 to 61 months (mean 22 months). Initially all patients showed marked papilledema, normal visual acuity, considerable enlargement of the blind spot area, and significantly delayed pattern reversal visual evoked potentials. During medical treatment eleven patients showed within 3-6 months a rapidly regression and normalization of papilledema, blind spot area, and visual evoked potentials. Eight patients continued in showing papilledema including disc gliosis, enlargement of blind spot area, and pathological visual evoked potentials. One patient developed optic nerve atrophy. The results indicated that repeated examinations of visual evoked potentials, when suspect of threatening visual loss has come up (papilledema, increased blind spot area, and field defects), might increase the change of diagnose of an optic nerve atrophy as early as possible.

Adolescent↗

[Retinal detachment in the aphakic eye (author's transl)].

The picture of retinal detachment following cataractextraction is studied in 86 cases of aphakic detachment, and the hypothesis that two different forms of detachment exists is proposed. In order to study this hypothesis the time-interval, the refraction and the type of tear is analysed. The results seem to indicate that two forms are present. The first one, the so-called "non: aphakic" detachment, appears in the predisposed eye and will occur after a short time-interval. The other form, the "true" aphakic detachment appears at a later stage and though this form more often shows no clear-cut tear the prognosis seems to be somewhat better.

Aphakia, Postcataract↗

Temporal lobe epilepsy and neuro-ophthalmology. Ophthalmological findings in 74 temporal lobe resected patients.

A survey is presented of the ophthalmological findings in 74 patients with drug-resistant temporal lobe epilepsy, who underwent unilateral anterior temporal lobectomy 1960-1969 at Rigshospitalet, Copenhagen. At follow-up, 1970-1971, one to ten years following the operation, 81% of the patients had no or only few seizures. Preoperatively 11% of the patients suffered from strabismus as compared to an expected frequency of 5%, but this trend just falls short of statistical significance. The visual acuity remained unchanged in all patients following the operation. Preoperatively a visual field defect was observed in 2 patients. At follow-up 51 patients had homonymous hemianopias, in 38 of them this was limited to the upper quadrants, and in 13 patients also included the lower quandrants, but was characterized as a total homonymous hemianopia in only 6 patients. The presence and extent of the visual field defects were correlated to surgical results, age at onset of epilepsy, age at operation, preoperative duration of epilepsy, presence of grand mal, preoperative complications, and neuropathological findings, but without observing any statistically significant conclusions. On the other hand, the extent of the postoperative visual field defect was significantly influenced by the side of the operation, with more and larger defects following right-sided lobectomies. In the 51 patients with postoperative hemianopias, this defect was either unobserved by the patient or regarded as a considerably less important handicap than the frequent and socially invalidating preoperative seizures...

Adolescent↗