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Biomedical subjects

H H Wolff

Publications and source records attributed to H H Wolff.

At least 109 records · Page 6Linked to original sources
PubMed1987

Cutaneous pseudolymphoma at the site of prior herpes zoster eruption.

A 55-year old woman with a history of herpes zoster in the dermatome supplied by the mandibular branch of the trigeminal nerve developed cutaneous red papules and umbilicated nodules within the same segment. The clinical and histological diagnosis was pseudolymphoma. The lesions showed a polymorphous infiltrate without germinal center formation. Immunologic phenotyping with monoclonal antibodies revealed the predominance of helper T cells and distinct compartmentalization of B and T cells. The lesions healed up within 7 weeks. The development of pseudolymphomas at the site of previous herpes zoster eruptions seems to be extremely rare.

Adult↗
PubMed1987

Two different XY-quadrivalent associations and impairment of fertility in men.

One sterile and one subfertile man with balanced reciprocal autosomal translocations, a t(9;15), and a t(14;21), were analyzed using whole mount pachytene spreads, histology, and semen analyses. In both probands with different types of quadrivalent complexes lack of pairing near the translocation breakpoints and significant associations with XY bivalents were found. Variability in the frequency of XY-quadrivalent contacts and an increase in late pachytene to 52% in t(9;15) and 90% in t(14;21) could be observed. The lower rate was associated with reduced postmeiotic spermatogenesis and the higher rate with complete spermatogenic arrest. In both translocation carriers the XY-quadrivalent association is considered to be the main cause for testicular malfunction rather than nonpaired segments in the multivalent complexes.

Chromosome Banding↗
PubMed1987

[Adamantinoid basal cell carcinoma].

The adamantinoid basal cell epithelioma is a clinically uncharacteristic but histologically typical variant of basal cell epithelioma characterized by a meshwork of stellate tumor cells.

Aged↗
PubMed1986

[Angiolymphoid hyperplasia with eosinophilia].

Angiolymphoid hyperplasia means an angiomatous tumor associated with a lymphoid and eosinophilic infiltrate. The bizarre shape of the blood vessels and atypias of the endothelial cells remind one of angiosarcoma, however, the clinical course is benign.

Angiolymphoid Hyperplasia with Eosinophilia↗
PubMed1986

[How do I treat dyshidrosiform eruptions?].

Dysfunction of sweat glands and acrosyringia are not involved in the pathogenesis of dyshidrosis. Clinically, dyshidrotic dermatitis (atopic, toxic, contact allergic, hematogen-allergic) and dyshidrotic tinea should be differentiated. Therapeutic possibilities comprise symptomatic topical and systemic treatment, whereas causal treatment is only possible in cases of tinea.

Combined Modality Therapy↗
PubMed1986

Are acrosyringia involved in the pathogenesis of "dyshidrosis"?

Investigations of dyshidrotic eruptions of various causes were done by conventional and electron microscopy. In all cases, the histological patterns were identical. The dyshidrotic vesicle is an intraepidermal, spongiotic lesion. The intraepidermal part of the eccrine sweat duct (acrosyringium) is not altered even by spongiosis. As the acrosyringium does not take part in formation of a dyshidrotic vesicle, the term "dyshidrosis" has to be regarded as a misnomer. Dyshidrosis is nothing but spongiotic dermatitis modified by the distinctive characteristics of palmar and plantar skin.

Eccrine Glands↗
PubMed1985

[Rapid electron optical diagnosis of skin viral diseases].

By means of electron of microscopy and the negative staining technique, virus particles of herpes, pox and papillomaviruses from skin lesions may be demonstrated in a rather simple and quick way. Advantages and limitations of this method are presented.

Diagnosis, Differential↗
PubMed1984

[Erythema chronicum migrans with Bannwarth syndrome (Garin-Bujadoux-Bannwarth meningopolyneuritis)].

A 54-year-old male had erythema chronicum migrans (ECM), lymphocytic meningitis, and intense pain radiating along the distribution of the corresponding dermatomal segments. Neurologic involvement, described as Bannwarth syndrome or meningopolyneuritis Garin-Bujadoux-Bannwarth, is a typical late manifestation of ECM infection and requires high-dose intravenous penicillin therapy.

Diagnosis, Differential↗
PubMed1984

[Finger varicose veins of the aged].

Palmar and finger varicosis is a common abnormality of the veins in the elderly. This often overlooked age-related condition is illustrated by three observations.

Aged↗
PubMed1983

[The sterile Behçet pustule: a typical skin manifestation of the Behçet syndrome].

Solitary pustules were excised from five patients with Behçet's syndrome and examined histologically, immunohistologically, and--in one case--by immunoelectron microscopy. Histologically the changes were largely confined to the venules of the middle and lower corium. The endothelium was swollen, in part the vascular walls were destroyed. In the perivascular spaces there was round-cell infiltration, mixed with numerous neutrophilic granulocytes, some of them disintegrated. Immunofluorescence-microscopy revealed perivascular deposition of complement C3 and C1q. In fresh lesions there were also IgG or IgM precipitates. Immuno-electron microscopy also demonstrated complement C3 subendothelially. Fibrin deposition and disintegrating neutrophilic granulocytes marked the leukocytoclastic vasculitis. Taken together the findings indicate that an immune-complex vasculitis takes part in the pathogenic mechanism of pustule formation in Behcet's syndrome.

Behcet Syndrome↗
PubMed1982

[Unusual dermatofibrosarcoma protuberans].

Case report of a recurrent histiocytic tumor with wide local spreading. Clinical findings and the course of the disease corresponded with the diagnosis of dermatofibrosarcoma protuberans. The histological findings did not correlate with this diagnosis. Signs of a typical histiocytoma with accumulation of hemosiderin and lipids were dominating. It will be discussed whether the clinical disorder of a dermatofibrosarcoma protuberans may be marked by distinctive histological criteria.

Aged↗
PubMed1982

Steatocystoma multiplex: anatomic reevaluation, electron microscopy, and autoradiography.

Histologic and electron-microscopic features of steatocystoma multiplex were investigated. Specimens from 25 patients (8 females, 17 males) were serially cut and three-dimensional drawings constructed. Steatocystoma multiplex is a nevoid sebaceous duct and sebaceous gland tumor, originating from sebaceous follicles, but is not a dermoid tumor. One pilary unit continuously produces vellus hairs, which are trapped in the cystic cavity or in the pilary canal (trichostasis). Steatocystoma multiplex is connected to the epidermis by a straight or meandering epithelial cord, the remnant of the follicular infundibulum. This infundibulum is a more or less solid strand, often containing sebocytes or sebaceous lobulelike structures. A lumen, partly present in a few areas of the cord, is filled with cellular debris of keratinocytes, corneocytes, sebocytes, or trapped hairs. Steatocystoma multiplex has electron-microscopical features similar to the sebaceous duct and sebaceous glands of sebaceous follicles. The 3H-thymidine labeling index of the cyst wall with or without sebaceous acini is lower than in sebaceous follicles. Steatocystoma multiplex suppurativum, characterized by spontaneous rupture of the cyst, inflammation and scarring, mimics acne conglobata with hidradenitis-suppurativa-like lesions as seen in the acne triade or tetrade.

Adolescent↗
PubMed1982

Action of isotretinoin in acne rosacea and gram-negative folliculitis.

Good to excellent clinical results have been obtained in the treatment of severe inflammatory acne (acne conglobata, acne fulminans, and acne conglobata with hidradenitis and dissecting cellulitis of the scalp) with orally administered isotretinoin (13-cis-retinoic acid). Similar promising results have been obtained in patients with severe rosacea and gram-negative folliculitis. Isotretinoin probably has multiple modes of action, including (1) inhibition of sebaceous gland activity, (2) inhibition of the growth of Propionibacterium acnes within the follicle, although the retinoid is not antibacterial, (3) inhibition of inflammation, and (4) alteration of the pattern of keratinization within the follicle, as demonstrated by light and ultrastructural studies.

Acne Vulgaris↗