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Biomedical subjects

H Höller

Publications and source records attributed to H Höller.

At least 37 records · Page 2Linked to original sources
PubMed1979

Disappearance from blood and urinary excretion of 35S-thiamin in sheep. A kinetic study.

In seven experiments with two adult sheep a single dose of 35S-thiamin was injected intravenously. Blood and urine samples were taken at short intervals after dosing and analyzed for 35S-radioactivity. The data obtained were subjected to a curve fitting computer program. The disappearance of 35S-thiamin from blood followed a three-exponential function; the average half-times of the three components were 0.4, 3.7 and 93.7 minutes. Urinary excretion of the tracer was also three-exponential and amounted to 19--32% of the injected dose over 150 minutes.

Animals↗
PubMed1978

[Socio-ecological study of the therapeutic milieu in a modern rehabilitation centre (author's transl)].

The article presents a data survey carried out by means of a questionnaire, the "ward atmosphere scale" described by Moos (1966--1974), U.S.A. In Austria, the effects of socio-ecological influences are examined for the first time at the rehabilitation centre in Hochegg. The data refer to autumn 1975. At that time attempts were made at Hochegg rehabilitation centre to develop a staff-centred guidance style and a client-centred therapeutic milieu in the sense of a therapeutic community. The patients were offered therapeutic programmes which were to the greatest possible degree tailored to their individual needs whilst not interferring with the patients' spontaneity and personal initiative. The analysis of the variables used in Hochegg are illustrated and compared with the mean values of the American results. It is pointed out that studies of existing conditions performed in an endeavour to create more human working conditions, are met with disapprouval. The first results of the survey are intended to be used as the basis for the improvement of the questionnaire and are helpful in decision-making regarding the development of therapeutic styles which meet the needs of the patient, regarding staff management and architectural influences.

Austria↗
PubMed1977

[Experiences with non-swimmers in the rehabilitation of adult clients (author's transl)].

The experiences with 595 adult non-swimmers receiving swimming instruction during the years 1974-1976 are discussed on the basis of selected and cited tape interviews. Theoretical reference systems are described against this background of empirical observations, e.g., Alfred Adler's interpretation of individual psychology - that one's style of living is influenced by early childhood experiences, human indifference or hostility. Recent works of brain physiologists are mentioned, which deal with the two forms of human consciousness: the verbalisation of linear, logic and abstract thoughts in the left hemisphere (in the case of right handed persons), and the specialisation of the right hemisphere in the perception of symbols, pictures and irrational feelings. The helpful effect of a non-directive, client-centered atomosphere is discussed. The behavioural changes in patients who learned to swim are compared with the hypothesis formulated by Hoppe - that psychosomatic diseases might be caused by a functional disconnection of the two hemispheres.

Adult↗
PubMed1976

Thiamine absorption in the rat. IV. Effects of caffeic acid (3,4-dihydroxycinnamic acid) upon absorption and active transport of thiamine.

The effects upon thiamine absorption in-vitro and in-vivo by caffeic acid (a thiamine antagonist isolated from bracken) was studied, partly using 14C-thiamine. It was again shown that caffeic acid reduced the quantity of thiochrome positive thiamine, dependant upon the concentration ratio caffeic acid/thiamine. Caffeic acid was able to pass across the intestinal wall and to exert its antithiamine effect in the serosal incubation fluid. When caffeic acid was present in the mucosal fluid the amount of thiochrome positive thiamine passed to the serosal side was diminished according to the mucosal caffeic acid concentration. In-vitro studies with 14C-thiamine revealed, however, that thiamine modified and turned into a thiochrome negative form by caffeic acid was absorbed similarly to unaffected thiamine. Active transport in-vitro of thiamine was significantly inhibited by the presence of caffeic acid.

Animals↗
PubMed1975

Thiamine absorption in the rat. ii. intestinal alkaline phosphatase activity and thiamine absorption from rat small intestine in-vitro and in-vivo.

The correlations between intestinal alkaline phosphatase (IAP) activity and thiamine absorption and glucose absorption were studied in the rat. An everted sac in-vitro technique was used in adult rats whereas in-vitro experiments were performed in young rats 10 days old. All incubation experiments were done with 14-C-labeled thiamine. The patterns of IAP activity along the small intestines differed greatly between young and adult rats but were closely paralleled by the distribution of active thiamine transport in adult rats and thiamine absorption in young rats, respectively. When IAP was specifically inhibited in adult rats by L-phenylalanine active thiamine transport in-vitro was abolished. No correlation was found between IAP activity and active transport or glucose in-vitro, nor did inhibition of the enzyme in any way affect glucose transport capacity. It is suggested that the enzyme intestinal alkalinephosphatase is involved in the process of active thiamine absorption.

Age Factors↗
PubMed1975

Thiamine absorption in the rat. III. Effect of ethyl alcohol on active absorption of thiamine in-vitro.

The effect of ethanol on active thiamine absorption in-vitro was studied in everted sacs of rat small intestines. Non-adapted, normally fed rats were used which had not previously been treated with alcohol. It was found that ethanol at 1% final concentration significantly increased active transport of thiamine to approximately fourfold. It is suggested that increased permeability of the intestinal wall plays a major role in phenomenon.

Animals↗