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H Haak

Publications and source records attributed to H Haak.

20 records · Page 2Linked to original sources
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A linked genetic marker for multiple endocrine neoplasia type 2A on chromosome 10.

Multiple endocrine neoplasia type 2A (MEN2A) is an autosomal dominantly inherited cancer syndrome characterized by medullary carcinoma of the thyroid, phaeochromocytoma and hyperparathyroidism. Almost all gene carriers can be detected by screening tests before the age of 40, but the nature and location of the predisposing gene are unknown. Simpson et al. recently reported preliminary evidence for linkage between the DNA probe p9-12A on chromosome 10 and MEN2A. We now report linkage between the MEN2A locus and the interstitial retinol-binding protein gene, which is located on chromosome 10p11.2-q11.2.

Centromere↗
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[Prospective randomized comparative study of early functional outcome of 2 knee joint endoprosthesis systems--rotation plateau versus fixed polyethylene inlay].

AIM: Different systems are used for total knee arthroplasty (TKA). Compared were a press-fit femur condyle replacement system with fixed tibial PE-inlay versus a rotating tibia component system with an emphasis on the early functional results. METHOD: Patient selection and the use of the Knee Society Score for this randomized and prospective study were based on the directives for TKA of the german Society for Orthopaedic and Trauma Surgery (DGOT). We examined the patients post-operatively after 1 week, 2 weeks, 6 weeks, 3 months, 6 months, and 1 year. RESULTS: After 6 weeks an increase of the total knee score could be seen in both groups. The total knee score of the rotating tibia component increased from 93.96 pre-operatively to 113.57 after 6 weeks, to 139.82 after 3 months, to 154.32 after 6 months, and to 159.65 after one year. The total score with the fixed PE-inlay increased from 79.75 to 111.5 after 6 weeks, to 128.25 after 3 months, to 134.08 after 6 months, and to 130.08 after one year. CONCLUSION: After 6 weeks the implant with the rotating tibia component showed a lasting higher score as compared to the implant with a fixed PE-inlay component using the same early rehabilitation and mobilization techniques.

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