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Biomedical subjects

H Halaburt

Publications and source records attributed to H Halaburt.

18 recordsLinked to original sources

[Acoustic neurinoma: observation prior to surgery].

During the period from 1977 to 1989 (both years included) 79 acoustic neurinomata were diagnosed in 76 patients in the County of Arhus. Twenty-four of these neurinomata were followed for varying periods clinically and radiographically. The symptoms of the patients and the results of successive computed-tomographic scans are mentioned. During the periods of observation, four patients were submitted to operation and operation was recommended in two cases. Seventeen patients are still under observation and are in good clinical condition with cessation or limited growth of the tumour in eight. These patients have been observed for between 1 and 13 years, on an average 4.5 years and are characterised by advanced age which averaged 61 years at the time of the diagnosis. The rate of growth of the tumour was calculated to be 1.1 mm per annum on an average with a variation from 0 mm to 4.8 mm per annum. As operative treatment of acouistic neurinoma exposes the patient to a not inconsiderable risk of deterioration the medical and/or socioeconomic status, the authors consider that an expectant and controlled attitude (wait and scan) is justified in elderly patients with acoustic neurinoma.

Adult↗

Spect bone scintigraphy in assessment of cranial Paget's disease.

Single photon emission computed tomography (SPECT) bone scintigraphy was used in the assessment of Paget's disease in 3 patients with skull involvement. In comparison with conventional scintigraphy, SPECT improved the three-dimensional perception and made precise outlining of involved bones possible. The radionuclide uptake in lesions expressed as counts per pixel was 1.5 to 10 times that of normal bones. Routine use of SPECT in cranial Paget's disease for staging and monitoring the effect of treatment is proposed.

Aged↗

[CT of fractures and ligament ruptures of the 1st and 2d cervical vertebrae].

On the basis of a patient material from a period of 14 months in a neuroradiological department, the fracture types in the first and second cervical vertebrae are reviewed. Computed tomography is found to be of particular value in cases of suspected fractures of the first cervical vertebrae, which is frequently found to be considerably more fragmented on computed tomography than in conventional x-rays, while fractures can be excluded in other cases. In cases of fracture of the second cervical vertebrae, computed tomography can reveal rotation of fragments of the body into the spinal canal while fractures of the dens may be overlooked if supplementary reconstructive sections are not carried out.

Cervical Vertebrae↗

Coronal CT examination in the evaluation of small frontoethmoidal encephalocoeles.

Symptoms producing small front-ethmoidal encephalocoeles are generally identified radiologically. The examination of choice is coronal CT, eventually performed axially with coronal reconstructions, and best with intrathecal contrast material delineating the basal cisterns. Two case reports demonstrate the clinical and radiological problems in identifying small fronto-ethmoidal encephalocoeles.

Adolescent↗

Predictive value of radiculography in patients with lumbago-sciatica. A prospective study (Part II).

One hundred patients with symptoms of lumbo-sacral root compression were prospectively and consecutively assigned to operation based alone on clinical findings. A preoperative myelogram was performed in all patients and described without a knowledge of the clinical features. All patients were explored for the clinically and myelographically relevant disc. When the myelogram was normal (16 patients) both lower lumbar interspaces were exposed. In 58 patients a herniated disc was revealed at surgery. Only "myelographic herniation" with indentation of the contrast column was accompanied by a high frequency of disc herniation at surgery (73-87%). In cases with normal myelograms only 5% had a disc herniation. The severity of the myelographic finding was clearly correlated to the frequency of positive surgical findings and good outcomes. The preoperative radiculogram gives a high degree of certainty in the preoperative evaluation whether a surgical lesion is present or not and reveals a precise prediction of the outcome of surgery.

Back Pain↗

Predictive value of clinical and surgical findings in patients with lumbago-sciatica. A prospective study (Part I).

In a prospective, consecutive study of patients with lumbar back pain and sciatica, various clinical features and surgical findings were evaluated in order to analyse the predictive value regarding (1) level of diseased interspace (2) presence and type of lesion responsible for root compression (3) outcome after surgery. One hundred patients underwent surgery solely on clinical grounds. Fifty-eight had disc herniation. The level of disc herniation was correctly predicted in three quarters of patients with a prolapsed disc. The outcome after surgery was good in 77 patients. Only few clinical features, namely male sex and scoliosis were predictors of a good outcome. Lasegue's sign was indicative of root compression in 90%, but only two-thirds had disc herniation. Conversely one-third had disc herniation in spite of a "negative" test. Lasegue's sign was not superior to other clinical tests in predicting outcome. The most important indicator of a good outcome was the presence of disc herniation at surgery. Patients with disc pathology other than true disc herniation fared equally with patients, who had normal discs disclosed at surgery. Myelography was undertaken in all patients prior to surgery, the results of which are analysed in the following paper. (Espersen et al.: Predictive value of radiculography in patients with lumbago-sciatica. A prospective study (Part II, Acta Neurochirurgica 73 (1984), 213-221.

Back Pain↗

Computerized tomography of malignant melanomas of the choroid.

Twelve histologically verified choroidal melanomas, 15 normal fellow eyes and 4 simulating lesions (vitreous haemorrhage, choroidal haemorrhage, retinal detachment and choroidal detachment) were CT-scanned before and after intravenous contrast media (maximal attenuation in the tumours were estimated from a computerized curve corresponding to a line placed from the center of the eye, through the tumour to the outside of the bulb). The melanomas showed significantly higher precontrast attenuation (54 HU) than the control eyes (17 HU) measured in symmetrical points. Enhancement was registered in all the tumours (mean = 22 HU, P less than 0.01), but not in the control eyes. Among the simulating lesions, the retinal detachment enhanced after contrast. Indications for CT-scan of intraocular processes are diagnostic doubt in opaque media and suspected extrabulbar extension. A patient with verified, disciform organised subretinal haemorrhage scanned after the primary series showed contrast enhancement comparable to the malignant melanoma series. Also 'CT-positive' tumour eyes have to be observed over a period.

Adult↗

Irradiation dose to the lens of the eye during CT of the head.

The irradiation dose to the lens of the eye during CT scanning has been measured in 16 patients. The dose is greatly influenced by changes in gantry angulation, the position of the patient, the thickness and number of slices, KV, and milliamperage. The total lens dose has been measured to be higher than previously reported. Repeated CT scans imply the risk of irradiation cataract, especially in infants and children.

Brain↗

The naevoid basal cell carcinoma syndrome. Clinical, biochemical and radiological aspects.

Eight living patients with the nevoid basal cell carcinoma syndrome (NBS) underwent a clinical and radiological examination, and data on a deceased patient was included. Cerebral CT-scannings were performed on eight patients, and calcification in the falx and tentorium cerebelli was found in all patients but one. Congenital hydrocephalus or agenesis of the corpus callosum could not be demonstrated. Laboratory results, including serum levels of alpha 1-antitrypsin and alpha 2-macroglobulin, haptoglobin, inorganic phosphorus, alkaline phosphatase and calcium, were normal in all patients but two. It is postulated that elevated serum alkaline phosphatase in patients with NBS is correlated to the presence of growing odontogenic keratocysts.

Adolescent↗

Cerebral abscess with special reference to the angiographic changes.

From 1961 to 1973 forty patients with surgically confirmed intracranial abscesses had preoperative cerebral angiography. The findings were abnormal in all cases but one. In 20 patients (50%) the primary diagnosis was a space-occupying lesion. In 19 patients (47.5%) an abscess was suggested by the presence of a capsule, the only finding definitely diagnostic of an abscess. Subtraction technique provided essential information in detecting the capsule. Angiography proved indispensable in suggesting the nature of the lesion.

Adolescent↗