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Biomedical subjects

H Hamood

Publications and source records attributed to H Hamood.

3 recordsLinked to original sources

[Acipimox (Olbetam) as a secondary hypolipemic agent in combined hypertriglyceridemia and hyperlipidemia].

32 patients with hypertriglyceridemia, excessive hypertriglyceridemia, and combined hyperlipidemia, were treated with the nicotinic acid derivative acipimox (Olbetam). First line treatment with bezafibrate, or statins in some with combined hyperlipidemia, had failed. In 10 acipimox was discontinued due to side effects or absence of clinical response. The other 22 completed 6 months of treatment with no side effects. Acipimox caused a significant 54% decrease in triglyceride levels, a 23% decrease in total cholesterol, and a 12% increase in HDL-cholesterol. LDL-cholesterol was difficult to calculate because of the high triglyceride levels, so no results are presented. Although acipimox was much better tolerated than nicotinic acid, it also had side effects, but fewer. Acipimox can therefore be used as a second-line drug, mainly in those with combined hyperlipidemia and hypertriglyceridemia.

Adult↗

An improved percutaneous jetting system for use during microlaryngeal operations.

Studies carried out in the laboratory have shown that an S-shaped cannula for trans-laryngeal jet ventilation provides a distinct advantage over conventional straight ones. Tidal volumes are larger and the cannula is more stable in position. The tendency of perforate the posterior wall of the trachea during introduction is also minimal. Blood gas data obtained from patients being operated upon with this technique of anaesthesia show that it provides very adequate ventilation and can be effectively used with balanced anaesthesia if a nitrous oxide-oxygen blender is incorporated into the jetting system. It can be put in position before induction of anaesthesia to enable preoxygenation and assist ventilation and can be left in place at the end of the operation until the patient is breathing adequately. If necessary, a tracheostomy can be done with the cannula in situ. It is not proposed that this should be the standard mode of anaesthesia or ventilation for patients undergoing operations on the larynx, but in stituations where other methods are not adequate and when significant upper airway obstruction is present, this is an excellent alternative.

Aged↗

Percutaneous jet ventilation.

A method of ventilation utilizing an S-shaped cannula placed through the cricothyroid membrane and hooked up to a conventional jetting system is described. Its advantages are reduced morbidity, better ventilation, and an unobstructed view of the operating site for the surgeon. The system allows ventilation of the patient with oxygen prior to the induction, or at the end of anesthesia if necessary, and allows the surgeon to perform a tracheostomy in the usual manner if it is indicated. The system is not proposed as a routine method of ventilation during anesthesia for laryngeal surgery but is reserved for cases in which other methods would not perform adequately.

Aged↗