Biomedical subjects
Publications and source records attributed to H Handel.
Ultrasonic diagnosis (A- and B-mode) is a non-invasive alternative without radiation exposure to the radiographic examination of the maxillary sinuses of children. Given the adequate prerequisites (high resolution device, trained examiner) diagnostic mistakes can be reduced to a minimum. Thus sonography becomes the first and frequently the only necessary diagnostic imaging procedure for diagnosing the puerile maxillary sinus.
Abdominal sonography should compulsory be used in patients with cystic fibrosis (CF). It is not difficult to detect early morphologic changes at liver, gall-bladder, pancreas, spleen, and vessels by ultrasound. As a non-invasive method sonography is a very useful tool for a comprehensive special care of outpatients with CF.
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201 children with healthy kidneys and 61 patients of the paediatric nephrological dispensary with chronically relapsing pyelonephritis without disturbance of the transport of urine were examined sonographically. With the help of an atrophy score was controlled, whether the summation of unspecific parameters is in connection with the length of the kidney. A correlation of the introduced point system with the size of the kidney could be proved. The atrophy score represented shall facilitate the sonographic control of the course of non-obstructive parenchymatous renal diseases.
In a prospective study 201 children with healthy kidneys were sonographically examined. Apart from the length unspecific parameters in the ultrasound tomogram, such as possibility to delimit the organ, echogenity and differentiation of the fine structure of the kidneys are demonstrated depending on age. The proportion of smoothly delimited kidneys before the 1st year of age was significantly lower than in the following years. With growing age the possibility to delimit mean echocomplex, renal medulla and renal cortex. In the 1st and 2nd trimenon the echo-richness of the kidneys is to be valuated physiologically. The demonstrated dynamics of sonographic signs shall alleviate the age-specific judgement of renal diseases without disturbance of the urine transport.
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The study is based on a material of 60 patients with chronic lymphocytic leukaemia of mild course with survival over 4 years. The method used was a comparison of the patients treated from the time of diagnosis establishment with the group of similar patients not treated throughout the whole period of follow-up and with another group of patients treated from the time of exacerbation of the proliferative process. The following data were taken into account: survival length, degree of splenomegaly and lymphadenopathy, leucocyte and platelet counts, haemoglobin level, infectious complications. It was demonstrated that cytostatic and/or hormonal treatment started at the time of diagnosis establishment did not prolong the survival. A statistically significant prolongation of survival time was observed, on the other hand, in cases treated from the time of exacerbation. Cytostatic agents increased the risk of infections and the risk of thrombocytopenia.
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