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Biomedical subjects

H Hanisch

Publications and source records attributed to H Hanisch.

3 recordsLinked to original sources

[Microsurgical, neuroprotective plaque isolation in plastic penile induration].

Conservative therapy of Peyronie's disease has not given very encouraging results. This means operative treatment strategies are the only effective therapy form that appears to be successful. Another treatment form, which often leads to a non-acceptable shorting of the penis, is the technique used in the Schröder-Essed and Nesbit procedures. Removal of the plaque, followed by a tissue transplant to cover the excision area, enables a correction of the deviation and maintenance of the original length of the penis. Because of the periodically described, possibly fatal results of postoperative perception disorders of the glans penis, preparation of the dorsal neurovascular bundle is performed under microsurgical conditions. Because of the certainty with which optical identification of nerves and vessels is achieved, it is possible to keep the nerves protected and to have atraumatic isolation of the plaque. After the first encouraging surgical results, we present the operative procedure under microsurgical conditions.

Arteries↗

[Computer assisted determination of left-ventricular contraction abnormalities using two-dimensional echocardiography. I. Analysis various study methods and determination of normal values].

In 181 patients without signs of heart disease we determined the normal contraction pattern of the left ventricle in the echocardiographic 2- and 4-chamber views by means of the shortening of 48 radiants and the changes of 5 pre-defined areas. We used an extracardiac fixed axis reference system and an intracardiac floating reference system. We also calculated in 68 of the patients the interobserver variability of the data in each evaluation method. We demonstrated that the range of normal contraction and the reproducibility in the area-change method with a floating axis system was smaller compared to the radial shortening method. The interobserver variability in the 4-chamber view was better than in the 2-chamber view. Using the intracardiac fixed reference system in both methods, deviation from normal and interobserver variability was not acceptable for the detection of left ventricular wall motion abnormalities in both apical views. In general, we could also demonstrate that the interobserver variability was better and the range of deviation was smaller in the apical 4-chamber view than in the 2-chamber view. The practicability and quality of the apical projections were superior to the parasternal projections in the long and short axis. We conclude from our studies that left ventricular wall motion abnormalities in the echocardiographic 2- and 4-chamber views could best be demonstrated by using an area-change method with an intracardiac floating reference system.

Arrhythmias, Cardiac↗

[Quantitative, computer-aided determination of left ventricular contraction abnormalities in two-dimensional echocardiography. II. Application in patients with coronary heart disease].

In 105 selected patients with documented transmural myocardial infarction and segmental wall motion abnormalities in the 2-dimensional echocardiogram we determined the sensitivity, specificity and predictive accuracy of a semi-automatic computerized wall motion analysis method. The extent and localization of the LV-contraction abnormalities were documented by visual inspection of the 2-D echocardiograms by two experienced cardiologists and confirmed by angiographic and coronarographic findings. These findings were compared with computerized evaluation methods using an area-change method (5 areas) and a radial shortening method in a floating axis reference system. In the 2-chamber and 4-chamber views the area-change method was more sensitive (2-CH: 70% vs 49%, 4-CH: 79% vs 72%) and had a higher predictive accuracy (2-CH: 90% vs 87%, 4-CH: 86% vs 82%) than the radial shortening method. The specificity between the two methods was not different. In both views, however, we found distinct regional differences between the apex and the anterior and posterior wall. We conclude from our studies that in patients with myocardial infarction, computerized wall motion analysis in the 2- and 4-chamber views is accurate and reliable as compared to the visual diagnosis of two experienced observers. The area-change method in an intracardiac floating system seems to be superior to the radial shortening method.

Angiocardiography↗