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Biomedical subjects

H Harazim

Publications and source records attributed to H Harazim.

13 recordsLinked to original sources
PubMed1987

An open randomised comparison of ofloxacin and doxycycline in lower respiratory tract infections.

The efficacy and tolerance of ofloxacin and doxycycline were compared in patients with lower respiratory tract infections. Doses used were 200 or 400mg twice daily for ofloxacin and 100mg twice daily for doxycycline. Of 230 patients treated, 219 could be assessed for effectiveness. 88 patients were treated for exacerbations of chronic bronchitis and 131 for pneumonia. Clinical cure was achieved in 18 of 52 patients with bronchitis treated with ofloxacin. Improvement occurred in 29 and failure in 5. In the doxycycline-treated bronchitis group 11 of 36 patients were cured, 22 improved and 1 failure occurred. Of 62 patients with pneumonia who were administered ofloxacin, 34 were cured, 26 improved and treatment failed in 2. In the doxycycline-treated group of patients with pneumonia 39 of 69 were cured, 23 improved and 7 failed to respond. Two patients experienced adverse effects during ofloxacin treatment and 7 while receiving doxycycline.

Anti-Infective Agents↗
PubMed1984

[Complications of the use of microcatheters using Grandjean's technic in ergometry].

The method of microcatheterism was described in the now usual form first by Grandjean in 1967. It offers an appropriate information about pressures in the pulmonary circulation at rest and during stress. This report gives a comprehensive survey about the complications with this method in a time range of seven years, from 1976 until 1982, in 4901 patients. The total rate of complications was very low (0.67%). Compared with a study about complications with Swan-Ganz-catheters in similar patients from Roskamm and co-workers, we found in our investigation a lower rate of dangerous arrhythmias. We conclude that microcatheterism is a simple, and cheap method, which is poor of risks. It is suitable ideally either for screening and control investigations or for the quantification of a cardiopulmonary disease.

Arrhythmias, Cardiac↗
PubMed1983

Clinical assessment of a trimethoprim-sulfamethopyrazine combination (Kelfiprim) in lower respiratory tract infections.

The new combination of trimethoprim 250 mg and sulfamethopyrazine 200 mg was used in fourteen out-patients and eighteen in-patients with acute exacerbation of chronic bronchitis, pneumonia or bronchopneumonia due to sensitive bacteria. The drug was given for 1 to 2 weeks as one capsule daily (following a double loading dose on the first day), and ampicillin, 500 mg capsules q.i.d., was administered to another group of eleven in-patients for comparison. Overall results, based on clinical, radiological and laboratory findings, were excellent or good in 85% and 67%, respectively, of out- and in-patients receiving the combination drug; definite failures were one out of fourteen and two out of eighteen cases, and the remainder were assessed as fair. In three out of thirty-two patients mild to moderate gastro-intestinal side-effects were observed during treatment. The drug compared favourably to ampicillin for both effectiveness and safety.

Adult↗