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Biomedical subjects

H Harboe

Publications and source records attributed to H Harboe.

7 recordsLinked to original sources
PubMed1989

[Bruising after venepuncture].

A randomized cross-over investigation was carried out on 24 healthy volunteers to investigate the occurrence of bruising following compression on the extended or flexed elbow respectively, following venepuncture in the cubital fossa. Following 48 uncomplicated venepunctures (24 x 2) a total of 8 (17%) were found to have bruising, four of these after compression on the extended elbow and four after compression on the flexed elbow. It is concluded that there are no differences in the frequencies of bruising following closed venepuncture in the cubital fossa regardless of whether the subsequent compression is undertaken on the extended or flexed elbow.

Adult↗
PubMed1989

Local irritation after administration of diazepam in a rectal solution.

The extent of local irritation after rectal administration of diazepam in solution was studied in 24 adults (mean weight of 70 kg). The trial was randomized using a triple cross-over design. A burning sensation was reported in 60%, 12% and 0% of subjects up to 15 min after administration of diazepam 35 mg, diazepam 10 mg and placebo, respectively. Endoscopic assessment 24 h after medication showed mechanical irritation in three subjects and local irritation probably caused by diazepam, the vehicle, or both, in four. No correlation was found between subjective complaints and objective findings. Control endoscopy 7 days after medication revealed no pathology. It is suggested that a rectal solution of diazepam in doses up to 0.5 mg kg-1 is a safe form of medication in respect of irritation of the rectal mucosa.

Administration, Rectal↗
PubMed1982

Intragastric balloon as an artificial bezoar for treatment of obesity.

A free-floating rubber balloon was installed as an artificial intragastric bezoar in five obese women. These patients were studied for a total of 272 days - i.e., 130 days with the balloon inflated (10 periods) and 142 days when the balloon was known to be deflated (7 periods). The balloons were easy to insert and reduced hunger. They remained inflated for 7 to 21 days (median 12 days) as judged by radioscopy. Collapsed balloons passed unnoticed with the stools. There were no complications associated with their use. During consecutive periods with balloon, without balloon, and with balloon average weight-losses over 10 days were: 5.0 kg (range 8.6 to 2.0), 0.5 kg (2.9 to 0.3), and 2.1 kg (2.6 to 1.2), respectively. The weight-loss observed while the balloons were inflated is promising but the efficacy of the method can only be evaluated when balloons which remain inflated for several months within the stomach become available.

Adult↗