Biomedical subjects

H Harnack

Publications and source records attributed to H Harnack.

4 recordsLinked to original sources

PubMed1991

Effect of continuous lumbar epidural anaesthesia during labour on fetal transcutaneous carbon dioxide.

The effect of epidural anaesthesia during labour on fetal transcutaneous carbon dioxide (tcPCO2) was observed on 27 fetuses. Our results show that in the course of epidural anaesthesia there is an increase in fetal tcPCO2. We can see a slight increase even before administering the test dose, while preparatory measures are undertaken for the epidural anaesthesia. After administering the test dose and after giving the main dose there is a further increase in fetal tcPCO2, which continues for up to 30 min after the main dose has been given. The results suggest that it is important to consider any pathological conditions in the fetus, so as to avoid the possibility of additionally endangering the fetus during epidural anaesthesia.

Adult↗

PubMed1990

The influence of oxygen administration to the mother during labor on the fetal transcutaneously measured carbon-dioxide partial pressure.

The aim of this study was to plot the course of the transcutaneously measured PCO2 (tcPCO2) in the fetus during oxygenation of the mother. In our examination 35 parturients with a suspicious or pathologic CTG were given pure oxygen for 10 minutes at a flow speed of 10 l/min. The fetal tcPCO2 was measured with a TCM 3 measuring device from Radiometer. The measuring temperature was 41 degrees C. The fetal tcPCO2 was 67.2 +/- 3.9 mmHg before the O2 application, during the O2 application it was 67.3 +/- 14.1 mmHg and for the period after the O2 application we found an average measurement of 66.7 +/- 13.9 mmHg. Further we investigated whether, depending on the original levels of the fetal tcPCO2 an O2 application to the mother had a measurable effect on the fetal tcPCO2 levels. The average levels of the tcPCO2 in the fetuses with pathological original levels of greater than or equal to 60 mmHg or with normal levels of less than 60 mmHg did not show any significant differences before, during or after the O2 application. Our own results and reports given in the literature about an increase in the fetal O2 partial pressure during maternal oxygenation lead to the conclusion that in cases with fetal hypoxia, the O2 application to the mother--in addition to other measures for intrauterine reanimation or speedy termination of labor--could be of advantage.

Blood Gas Monitoring, Transcutaneous↗

PubMed1977

[The effect of anesthesia on the postoperative behavior of liver enzymes and protein fractions].

Liver tests were performed postoperatively on 25 women with "healthy" livers. Patients were divided into 3 groups according to the type of anesthesia used: 1. halothane; 2. neuroleptic; 3. peridural. In all 3 groups the variations in serum proteins and liver enzymes were similar up to the 15th postoperative day. Variations of LDH, AP, LAP, and CHE were within normal range; slight to moderate increases above normal were observed for GPT, GOT, GLDH, and gamma-GT. All 3 groups barely differ with respect to enzyme levels during the postoperative course. We therefore interpret these changes to indicate a reaction of the liver to the stress of operation rather than to the mode of anesthesia.

Adult↗

PubMed1976

[Liver function in undisturbed pregnancy].

In order to evaluate liver function during pregnancy the enzyme activities of GPT, GOT, GLDH, LDH, AP, LAP, gamma-GT and CHE were determined in 272 healthy pregnant women from the 16th week of gestation up to term. The normal range of GPT, GOT, GLDH, LDH, gamma-GT and CHE did not differ significantly from those in non-pregnant women. Increases in AP and LAP are conditioned by placental synthesis. The functional reserves of a healthy liver obviously suffice to compensate for increased demands during pregnancy. Increases in enzyme aktivities during pregnancy are not physiologic - except for increases in AP and LAP.

Alanine Transaminase↗