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Biomedical subjects

H Haschek

Publications and source records attributed to H Haschek.

At least 19 recordsLinked to original sources
PubMed1984

[Transurethral electroresection with postoperative betatron irradiation in bladder cancer: indication and results].

100 patients suffering from infiltrating urinary bladder cancer underwent transurethral resection followed by external megavolt irradiation (Betatron) are presented. The value of irradiation and its role in the actual therapeutic concept is discussed. The results of the combined therapy in infiltrative urinary bladder cancer using transurethral resection and megavolt irradiation are demonstrated according to stage (T2, T3) and histological grading (G2, G3). The 5-years survival rate amounts around 80%, in deep infiltrating bladder cancer about 50%. The morbidity of postoperative megavolt therapy was negligible. The results are superior to megavolt therapy alone and approach the one achieved by radical surgery; in addition the possibility of salvage-cystectomy remains open.

Adult↗
PubMed1984

[Changes in the vena cava in kidney tumors: sonography or cavography?].

In seven out of 45 cases with malignant growths in kidneys and adrenal glands, sonography presented tumor-induced changes in the vena cava. The accuracy of this technique in detecting changes in the vena cava corresponds to that of cavography. Thus, it is no longer necessary to use cavography--except as a supplementary method mainly in cases where with sonography it is difficult to differentiate between an incomplete and a complete occlusion of the vena cava or between a cone-shaped invasion of the neoplastic thrombus into the inferior vena cava and an infiltration of the tumor into the wall of the vena cava.

Adenocarcinoma↗
PubMed1984

[Problems in bacterial hospitalism].

All over the world nosocomial infections are increasing at an enormous rate. With 30% urology takes second place, after intensive care units. Nearly 40% of these infections start in the lower urinary tract, and more than 7% are the direct cause of death. Attention is drawn to the increased financial burden caused by these complications. A consideration of the causes (above all uncritical use of antibiotics for prophylaxis and therapy) is followed by a discussion of the success of a change in policy concerning antibiotics and improved hospital hygiene in our own department. Lessening the selective pressure led to a very significant reduction of nosocomial problem germs and an increase in germ sensitivity, besides saving up to 80% of antibiotics.

Adult↗
PubMed1983

[Cryogenic surgery of prostatic adenoma: an enrichment of our surgical possibilities?].

On the basis of our experience of 410 operations and constant contact with the most prominent exponents of this new method we feel able to draw the following conclusion; cryosurgery of prostate adenomas with good equipment is a palliative method with little danger which can be used to advantage in maximum-risk patients with indwelling catheters and large adenomas. The success rate is 70-80%, whereby this falls to 50% after 5 years. Since it is difficult to classify patients as "maximum-risk" from an internal point of view, we must reckon that the evaluation is too unfavourable in around 20%.

Cryosurgery↗
PubMed1979

[Renal carcinoma (author's transl)].

A brief discussion of the epidemiology and aetiology of renal carcinoma is followed by a description of the clinical features. Attention is drawn to the significance of haematuria, especially microhaematuria and the para-neoplastic syndrome (toxic and endocrine tumour effect) in establishing an early diagnosis. Intravenous urography still remains the most important diagnostic procedure, whilst renal angiography is indispensable for the precise definition of tumour localization and extension. It is possible to solve most of the problems of differential diagnosis (primarily distinguishing between cyst and tumour) by means of renal angiography and sonography. Therapy is still based on surgical treatment, transperitoneal, "radical" tumour extirpation leading to an improvement in the results in about 15% of the cases, especially in stages III and IV. A 5-year survival rate may be expected in 60 to 70% of stage I and stage II cases, in about 40% of stage III and only a few percent of stage IV cases. Cytostatic therapy offers no improvement in results at the moment. Irradiation before and after surgical treatment, as well as hormonal medication produces a modest rise in the 5-year survival rate. The decisive factor is early diagnosis of renal carcinoma, because about half of all patients show evidence of metastasis already at the first examination.

Humans↗
PubMed1979

[New aspects in the treatment of elderly people with carcinoma of the urinary bladder (author's transl)].

50% of the patients with carcinoma of the bladder are older than 70 years. During the first examination a deep muscle invasion was found in about 60%. (Stages T3/T4. This situation makes forced surgical intervention in most cases impossible (e.g. radical cystectomy and segmental resection), therefore the transuretheral resection has to be the leading therapeutical procedure. During the past 10 years 80% of the bladder cancer patients were treated by TUR most ofter followed by external irradiation. The 3-year-survival rate now shows better results than before 1968 when TUR was performed in only 10% of the cases. During the period between 1968-1974 90% of the patients with superficial bladder carcinoma were still alive after 3 years, in comparison with only 52% between 1953-1967. The figures for patients with deeply invasive bladder carcinoma now shows 18% in comparison with 12%. The 3-year-survival rate for all stages shows an increase from 24% to 44%. Discussion of these results.

Age Factors↗
PubMed1979

[New possibilities in diagnosis and therapy of renal carcinoma (author's transl)].

A brief discussion of the aetiology and epidemiology of renal carcinomas is followed by a description of the clinical features. Attention is drawn to the significance of symptoms emphasizing the importance of early diagnosis. Intravenous urography still remains as the most important diagnostic procedure. It is pointed out that sonography and computer-tomography are now established as newer diagnostic methods, i.e. in distinguishing between cyst and tumor, in renal masses. Therapy, is still based upon surgical treatment. Transperitoneal, radical tumornephrectomy as compared with simple lumbar nephrectomy, has improved 5-year survival rate up to 16% especially in stage III tumors. Extracorporeal surgery for single kidney patients as hyperthermic surgery constitute new surgical methods, but only for specifically equiped urologic clinics. Embolisation of renal cell carcinoma is also used as therapeutic management in largely progressed tumors, and also used, as a preoperative measure, for the reducement of tumor size. Irradiation, before and after surgical treatment, as well as cytostatic therapy, revealed no significant improvement. We have reason to hope that progress in the research of hormonal- and immunotherapy will improve 5-year survival rate, in renal cell carcinoma.

Adolescent↗
PubMed1978

[Operative treatment of prostatic adenoma (author's transl)].

The indications for operative treatment of prostatic adenomas are outlined. The three operative techniques (suprapubic adenomectomy, resection and cryosurgery) should not be considered rival procedures, but complementary methods of therapy. The postoperative mortality dropped from 5.64% in the years 1957-1967 to 1.01% during the last decade mainly due to the implementation of electroresection and cryosurgery in high-risk patients. The advisability of early surgery is pointed out.

Adenoma↗
PubMed1977

[A new method for the determination of steroidal hormones in biological material (adrenal tissue) (author's transl)].

A rapid method is described for the determination of some steroidal hormones in adrenal tissue. The following steroids were measured: pregnenolone, progesterone, deoxycorticosterone, corticosterone, aldosterone, 17-alpha-OH-pregnenolone, deoxycortisol, cortisol, cortisone, 17-alpha-OH-progesterone, dehydroepiandrosterone, androstendione, and testosterone. After extraction of the steroids the purification steps were performed by thin layer chromatography. Gas chromatography was used for further separation and quantitative analysis of underivatized steroids. The GC-analysis of steroids without any derivatisation makes this procedure comparatively simple and exact. Recovery of the steroid content of the tissue ranged from 30% to 70%. This method described herewith has several advantages, and allows the analysis of two tissues at the same time for a large number of adrenal steroids within two weeks.

Adrenal Cortex Hormones↗
PubMed1976

Cryosurgery of prostate adenoma: evaluation of the method.

For a small group of high-risk patients with prostate adenoma, cryosurgery should be the method of choice (about 5-10+ of all cases). This intervention is only a palliative measure. The regrowth of residual adenoma is minimal. The clinical importance of this new technique is greater for those urological schools preferring the open surgical approach compared to those mainly performing transurethral resection.

Aged↗
PubMed1975

[Chronic headache and abuse of phenacetin (author's transl)].

70% of all patients who abuse phenacetin have headache. The nephrological aspects are reported of 240 patients who were phenacetin-dependent and in an average of 19 years had consumed an average of 6 kg - up to 25 compound powders daily. The degree of renal damage depends principally on the duration and regularity of ingestion of analgesics, and less on the total quantity. One fifth of the patients were already in a condition in which a fatal outcome was inevitable when they were admitted to hospital.

Anemia, Hypochromic↗