Biomedical subjects

H Hautzinger

Publications and source records attributed to H Hautzinger.

3 recordsLinked to original sources

PubMed1986

Rationale for and results from a randomised, double-blind trial of tetrachlorodecaoxygen anion complex in wound healing.

Local tetrachlorodecaoxygen anion complex (TCDO) had three therapeutic effects in difficult wounds, substantiated on day 14 in a multicentre double-blind randomised clinical trial on 271 inpatients with 0.9% saline as control. Wound cleansing was intensified, the formation of new tissue (granulations, epithelium) was promoted, and, irrespective of the different wound types, wound surfaces decreased more quickly, by a factor of 2.4. A novel quantity (eta) was derived as an indicator of wound healing promotion. eta NaCl (= -0.14) did not differ among different wound diagnoses. eta TCDO values were significantly better in relation to wound diagnosis, to smear (detritus), and to epithelialisation. Local TCDO was well tolerated.

Administration, Topical↗

PubMed1986

Regression analysis of aggregate accident data: some methodological considerations and practical experiences.

In empirical traffic safety studies regression analysis is perhaps the most widely used statistical technique. In the great majority of cases the regression model is applied in its standard form. If, however, highly aggregate accident data are analyzed, usually most of the assumptions of the standard model are violated. Referring to a practical study it is demonstrated how it may become difficult to decide whether or not a certain variable can be regarded as truly "explanatory." It appears that even in seemingly unproblematic situations contradictory results are obtained from only slightly different model specifications. It is recommended that the use of highly aggregate accident data be avoided whenever possible. Some hints are given concerning the use of appropriate extensions of the classical linear regression model in road accident studies.

Accidents, Traffic↗

PubMed1984

[Stimulation of wound healing by tetrachlordecaoxide. Results of a randomized double-blind study].

In 38 patients with chronic therapeutically resistant wounds, which, in 25 cases, had been existing for more than one year, Tetrachlorodecaoxide ( TCDO ) in a water solution containing glycerin was analyzed for its capacity to induce wound healing and compared in this respect to the standard in moist wound treatment, physiological sodium chloride. The results of the clinical trial demonstrate that the TCDO solution is significantly superior to physiological saline in local wound treatment regarding the degree of wound smear reduction, the formation of wound granulation tissue, the stimulation of epithelisation on the wound borders and the shrinking of the wound surface. The differences in therapeutic efficiency are so large that, in spite of the relatively small patient samples (21 + 17) it was possible to verify the superiority of a method for wound treatment in a randomized double blind clinical trial.

Aged↗