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Biomedical subjects

H Heesen

Publications and source records attributed to H Heesen.

14 recordsLinked to original sources
PubMed1982

[Personal and psychosocial problems in mastectomy for breast cancer and the possibility of adjustment].

Parts of the results of single interviews of 34 patients with carcinoma of the breast are reported. A team of physician, psychologist, and the patients themselves worked out the interviews. These were then coded and analyzed. 10 patients said that they had found it especially difficult to overcome the problems caused by their illness due to the loss of their jobs because of bureaucratic reasons. 5 patients got into financial troubles. The patients tried to get back to their previous jobs, hobbies, social contacts and holiday habits as soon as possible. In all cases the illness caused a more anxious observation of bodily sensations. 19 patients felt the loss of the breast as a heavy diminution of their female identity. These reactions were strongly influenced by the reactions of their male partners and the loss of their jobs. The loss of the breast and the awareness of the disease partly negatively, partly positively changed the emotional state and family life and in many cases caused a change of sexual behaviour. Overprotection and questions regarding the patients' health were generally felt to be stressful. 17 patients tried to avoid obtaining complete information on the disease. They were afraid of contradictory views presented by the mass media or by fellow patients they met in waiting rooms, in convalescent sanatoriums, or in self-help groups. Although, still aware of their disease, 23 patient regained a fully satisfying life-style, 3 were ambivalent. The most important factors in overcoming the problems were family, friends, and the patients' own ability to adapt. The psychosocial care was entirely insufficient, although the patients showed a great readiness to cooperate.

Adaptation, Psychological↗
PubMed1977

[Alteration of potassium metabolism by cardiac glycosides in suicidal intoxications (author's transl)].

The potassium concentrations in erythrocytes, serum and urine were continously determined in 3 patients who had taken acetyldigoxin (45 to 100 tablets Novodigal à 0,2 mg) in order to commit suicide. In the first 3 to 8 hours after ingestion of digitalis the potassium concentration in serum increased while the potassium concentration of erythrocytes declined a little. The elimination of potassium with the urine remained still normal. After this period of time the potassium concentration in serum and in erythrocytes considerably fell, simultaneously large amounts of potassium were excreted with the urine. It was not until after 14 days that the potassium metabolism normalized.

Cardiac Glycosides↗
PubMed1975

[Treatment of severe digitalis-intoxication in suicidal attempt (author's transl)].

4 patients tried to commit suicide by ingestion of 45 to 100 tablets of digoxin (Lanicor 0,25 mg) and acteyldigoxin (Novodigal 0,2 mg) respectively. In all patients cardiac arrhythmias occurred including 3 rd degree av-block, tachyarrhythmias and ventricular fibrillation which was lethal in two patients. After a short period hyperkaliaemia a rapid decrease of potassium in the serum was observed 3-12 hours after administration of digoxin. This loss of potassium was due to an increased excretion of potassium and sodium in the urine. It is thought that a reversible tubular leakage is responsible for the loss of electrolytes by the kidney rather than an inhibition of the ATPase in kidney tissue. From our observations the following therapy scheme for digitalis-intoxication is recommended: 1. Gastric lavage and administration of absorbents (charcoal, cholestyramin) in order to decrease the absorption of the glycosides and to interrupt the enterohepatic circulation. 2. Substitution of electrolytes by infusions and by oral route to balance sodium and potassium levels in the serum. 3. Administration of diphenylhydantoin for treatment of cardiac arrhythmias. 4. Implantation of a temporary pacemaker for treatment of cardiac arrhythmias especially for the management of bradycardias. 5. Plasmapheresis to lower the glycosid concentration in the heart muscle and in other tissues.

Adult↗
PubMed1975

[Thiamine and thiamine pyrophosphate in obsese patients during partial and total fasting (author's transl)].

The development of vitamin B1 (thiamine) deficiency was investigated in 17 obese patients in the course of a 1000 calory diet or during total fasting for a fortnight. Compared with normal persons no changes of concentrations of total thiamine, TPP, and pyruvate in the blood; thiamine excretion in the urine, or activiation coefficient of the eryhrocyte transketolase (alphaETK) were observed during the reducing diet. However, during a fortnight's total fasting all values decreased significantly to those of thiamine deficiency. The thiamine pyrophosphate (TPP) levels in the blood dropped from the 1st to the 14th day, whereas the alphaETK rose accordingly and the pyruvate levels showed a delayed rise. Total thiamine content of the blood and thiamine excretion in the urine only showed significantly different values when comparing the 1st and the 14th day. There was no dependency of thiamine excretion on urinary output. Clinical symptoms of thiamine deficiency could be demonstrated in no case.

Diet, Reducing↗