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Biomedical subjects

H Heidt

Publications and source records attributed to H Heidt.

6 recordsLinked to original sources

[Microbiologic findings in protracted and chronic enterocolitis].

Novel diagnostic methods (immunoblotting, immunofluorescence test) have been proved to be very sensitive and specific for detecting enteropathogenic bacilli. 28 patients with chronic enterocolitis were investigated. In 50% (14/28) of these patients Yersinia enterocolitica could be visualized in biopsies by immunofluorescence. The serum of 8 patients also contained IgA-antibodies against plasmid encoded released proteins of Y. enterocolitica. This paper reports evidence for persistence of Yersinia bacilli in a group of patients with chronic enterocolitis. Further studies must show, if these results may have therapeutic implications.

Adolescent↗

[Malignant somatostatinoma of the papilla major and minor].

In a 50-year-old man with extrahepatic cholestasis and iron-deficiency anaemia, local operative excision of a 4 cm submucous tumour of the papilla of Vater revealed on histological and immunochemical examination a somatostatinoma. Subsequent duodenopancreatectomy further demonstrated in the surgical specimen a lymph node metastasis and a 5 mm somatostatinoma in the papilla minor. The patient has now been free of symptoms for 12 months on substitution treatment with pancreatic enzymes.

Adenoma, Islet Cell↗

Sleep patterns in cat induced by gammahydroxybutyric acid.

Intravenous injections of gammahydroxybutyric acid (GHBA) (150-200 mg/kg) induce desynchronized sleep (DS) in the cat. This was shown by recording the EEG, eye-movements, the neck EMG, heart-rate and arterial pressure. The decreases in arterial pressure were not different from those recorded during naturally occurring DS. GHBA, given at doses above 200 mg/kg induced anaesthesia, during which arterial pressure was elevated. At the end of GHBA-induced sleep or anaesthesia there was a stage during which the animals were ataxic. The EEG showed a hypersynchronous spike pattern and arterial pressure was markedly elevated.

Animals↗