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H Hetzel

Publications and source records attributed to H Hetzel.

42 records · Page 3Linked to original sources
PubMed1977

[Influence of the age of old primiparae on the perinatal infant morbidity and mortility (author's transl)].

157 old primiparae (greater than 30 a) have been compared to a randomised control group of primiparae between the 16th and 30th year of age. In addition to the perinatal infant mortality rate, the number of children with malnutrition, the frequency of premature babies, the presence of a low Apgar score (less than or equal to 7) and pathological pH-values in the umbilical artery (pH less than or equal to 7,10) were cheked. Moreover the frequency of early neonatal morbidity (presence of one of the following criteria: 1 minute Apgar score less than or equal to 7, pH of the umbilical artery less than or equal to 7, 10, a transitoric or severe RDS and neurological complications during the newborn period) was investigated in both groups. In the group of the old primiparae a significantly higher perinatal infant mortality rate was found compared to the control group (3,8% versus 0,6%, p less than 0.05). The rate of small for date babies was remarcably higher than in the control group (14,6% versus 6,4%, p less than 0.05). There was no difference in the prematurity rate in both groups. The children of old primiparae had more frequently a low Apgar score (less than or equal to 7) than infants of the randomised control group (18,5% versus 11,5%), but the difference is statistically not significant. Furthermore no difference in the number of pathological pH values in the umbilical arteries (pH less than or equal to 7, 10) were found in the both groups. The children of old primiparae show a higher early neonatal morbidity rate compared to the control group (21.7% versus 14.0%); however, the difference is statistically not significant. According to our results the risk for the newborns is increased already with primiparae over 30 rather than 35 years of age.

Adult↗
PubMed1977

[The development of the perinatal mortality at the university department for women in Innsbruck from 1969 to 1975 (author's transl)].

In a retrospective study the development of the perinatal mortality at the University Hospital for Women in Inssbruck was reviewed. Among a total of 14,839 deliveries, 323 perinatal deaths according to the WHO definition were reviewed. The years from 1969 to 1971 prior to the introduction of intensive monitoring and the years 1972 to 1975 after the introduction of monitoring were compared. The perinatal mortality was reduced from 27.7 per 1000 in 1969 to 13.7 per 1000 in 1975. The decrease was due to intensive monitoring during labour. The Caesarean Section rate rose from 3.17% in 1969 to 8.53% in 1975. The increase was mainly due to fetal indications. Conditions which were of special obstetric interest in the context of intensive antenatal care were especially reviewed. It was surprising the preeclampsia accounted for the same number of perinatal deaths in the second portion of our review as in the first. Prematurity accounted for 60--70% of the perinatal mortality and received the focus of the efforts to reduce the perinatal mortality. The perinatal mortality of infants with a birth weight of less than 2500 grams was reduced from 224.0 per thousand in 1969 to 140.0 per thousand in 1975. This result was obtained by excellent co-operation with the pediatricians. The rate of premature deliveries remained unchanged at between 8 to 9% inspite of all efforts. The possible causes for this phenomenon are discussed. The perinatal mortality was higher in cases who had antenatal care by obstetricians and general practitioners not affiliated with the University Department. The timely referral of high risk cases to a regional perinatal centre is stressed again.

Austria↗
PubMed1976

[The problem of Caesarean section (author's transl)].

The Caesarean sections at the Universitäts-Frauenklinik Innsbruck from January 1st, 1969 to December 31st, 1974 have been surveyed. Related to the total number of 12 579 deliveries 627 Caesarean sections have been performed. Two 3-year-intervals have been compared: 1969-1971 (group I) without and 1972-1974 (group II) with modern practices of prenatal supervision. There was a high significant increase of the section rate in group II (5,8% versus 4,1% which has been related to the increasing number of mainly fetal indications. The maternal morbidity didn't rise with the increasing section rate. A significant decrease in total infant mortality rate and mortality rate at vaginal deliveries has been found with the increasing incidence of Caesarean sections; whereas the number of depressed infants (Apgar score less than 7) was increased in group II. The reasons therefore have been discussed. The rise of the number of Caesarean sections in group II performed because of breech presentation (14,2% versus 6,2%) was correspondent with a statistically significant decrease in the mortality rate from 11,7 to 4,1%. A Caesarean section rate between 7% and 10% seems to be the limit at least in our hospital--the total infant mortality rate cannot be reduced by further increasing the section frequency: the infant mortality rate possibly could be lowered by a better and more wide spread prenatal care especially by taking more care for prematurity and by intensifying the perinatal period.

Apgar Score↗
PubMed1975

[An unusual cause of sensitization against the Rh factor].

A case of Rh-sensitization is reported which was caused by the intra-muscular injection of blood from the patient's husband during the first pregnancy as treatment for hyperemesis gravidarum. The first infant showed a mild erythroblastosis. The second infant suffered of a severe erythroblastosis. The literature is reviewed and the causes of Rhesus sensitization are discussed.

Adult↗
PubMedDate not supplied

Neopterin, a marker of cell-mediated immune activation in human pregnancy.

High neopterin excretion is closely associated with activation of cell-mediated immunity. We studied urine and serum neopterin concentrations and serum interferon-gamma concentrations in normal pregnant women. In our study population, neopterin concentrations exceeded the normal range in 663 of 840 samples (79%). Neopterin levels increased with the time of pregnancy. Serum samples drawn from women in the third trimester of pregnancy also showed high neopterin concentrations in almost all cases; however, no circulating interferon-gamma was detected. Whereas neopterin is able to penetrate into the blood stream because of its small size (M = 253 D), diffusion of interferon-gamma is limited. Raised neopterin levels provide evidence for activated cell-mediated immunity during pregnancy.

Adult↗