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Biomedical subjects

H Heymann

Publications and source records attributed to H Heymann.

At least 37 records · Page 2Linked to original sources
PubMed1987

Neopterin. A tumor marker in colorectal carcinoma?

Neopterin is compared with other tumor markers in colorectal carcinoma. Its sensitivity is clearly lower than that of CEA, TPA and CA 19/9 and is even lower than the sensitivity of the erythrocyte sedimentation rate. The ability of neopterin to discriminate between different tumor stages is also lower than that of the other markers. The discriminant analysis shows that measurement of neopterin in the serum of patients with colorectal carcinoma gives no essential additional information.

Adult↗
PubMed1986

[Therapeutic possibilities in adhesions].

Laparotomy was performed on 36 patients with persistent "adhesion complaints". Good therapeutic success was obtained from detachment of omental adhesions on the abdominal wall and of omental cords from the minor pelvis as well as from adhesiolysis in the hypogastric region. No peritoneal adhesions at all were recorded from nine patients, although they had undergone several operations before. Complaints were removed from one third of all patients, while nearly 20 per cent were improved. One death occurred, following exploratory laparotomy, due to stress-induced ulcer perforation. No peritoneal adhesion had been present in that case. No complications at all were experienced with any of the other patients.

Abdomen↗
PubMed1986

[Diagnostic error: incarcerated hernia].

Reported in this paper are 19 patients on whom incarcerated hernia had been pre-operatively diagnosed, which proved to be wrong during the operation. Various types of inflammation, including appendicitis in the hernial sac, as well as accumulation of pus in the hernial sac and abscesses, were the disorders which had led to false diagnosis in ten cases. Tumours were recorded from four patients and cysts in the round ligament of the uterus from another three, while a funicular hydrocele was detected in one patient. In one case, painful swelling through haematoma in the inguinal region had been caused by ruptured aortic aneurysm. Ultrasonographic diagnosis is recommended for all dubious cases. Surgery should be considered a preferable option in situations of lasting uncertain diagnosis, in order to avoid incarceration from remaining unnoticed.

Adult↗
PubMed1985

Nontraumatic perforations of the small intestine.

Nontraumatic perforation of the small intestine is very rarely found as a cause of acute abdominal disease. A series of 15 adult patients admitted to our hospital from 1973 to 1983 is reviewed. Underlying conditions were primary neoplasia (three patients), adhesions (three patients), intraluminal foreign bodies (two patients), metastases (two patients) and diverticulum (one patient). In four patients, the pathogenesis remained unclear (idiopathic perforations). As surgical therapy, resection and anastomosis is preferred in order to make a thorough histologic examination of the perforated bowel possible. A possible role of local drug toxicity in the pathogenesis of perforations has been discussed herein. No anastomotic leakage was observed. Four patients died (27 percent).

Adolescent↗
PubMed1985

[Hyperbaric oxygenation in burns].

Standardised third degree burn injuries were produced in guinea pigs and a standardized pseudomonas aeruginosa infection model was used. Therapy with oxygen under high pressure (OHP) was initiated for not experimentally infected burn wounds and for wounds contaminated with a constant number of bacteria from a certain pseudomonas aeruginosa strain. The healing process was documented by wound area determination, histological examination, and bacteriological evaluation. Not treated uninfected wounds showed better results than the ones that were treated with OHP. Infected burn wounds also healed better when they were not treated than the wounds in which OHP therapy was initiated with some delay. The immediate and consistent application of OHP therapy led to a significantly improved healing of burn wounds infected with pseudomonas aeruginosa.

Animals↗
PubMed1979

Isolation of atypical lipopolysaccharides from purified cell walls of Pseudomonas cepacia.

Wall fragments were prepared from two strains of Pseudomonas cepacia and from P. aeruginosa, and their contents of readily extractable lipid, pronase-digestible protein and lipopolysaccharide were measured. Lipopolysaccharide extracted from P. cepacia, although biologically active, contained no detectable 2-keto-3-deoxyoctonic acid, but contained phosphate, rhamnose, glucose, heptose and hexosamine in concentrations comparable to those found in P. aeruginosa.

Cell Wall↗
PubMed1979

Fourteen-year survival of Pseudomonas cepacia in a salts solution preserved with benzalkonium chloride.

A strain of Pseudomonas cepacia that survived for 14 years (1963 to 1977) as a contaminant in an inorganic salt solution which contained commercial 0.05% benzalkonium chloride (CBC) as an antimicrobial preservative, was compared to a recent clinical isolate of P. cepacia. Ammonium acetate was present in the concentrated stock CBC solution, and served as a carbon and nitrogen source for growth when carried over into the salts solution with the CBC. The isolate's resistance to pure benzalkonium chloride was increased step-wise to a concentration of 16%. Plate counts showed 4 x 10(3) colony-forming units per ml in the salts solution. Comparison of growth rates, mouse virulence, antibiotics resistance spectra, and substrate requirements disclosed no differences between the contaminant and a recently isolated clinical strain of P. cepacia. The results indicate that it is critical that pharmaceutical solutions containing benzalkonium chloride as an antimicrobial preservative be formulated without extraneous carbon and nitrogen sources or be preserved with additional antimicrobial agents.

Animals↗
PubMed1978

Resistance of spheroplasts and whole cells of Pseudomonas cepacia to polymyxin B.

Sucrose-lysozyme spheroplasts were prepared from two strains of Pseudomonas cepacia and tested for susceptibility to polymyxin B and benzalkonium chloride. Spheroplasts were more susceptible than whole cells to benzalkonium chloride but not to polymyxin B. Disruption of the outer membrane layer was not by itself sufficient to render P. cepacia susceptible to polymyxin B.

Drug Resistance, Microbial↗
PubMed1978

[Postpyloric resection of a complicated ulcer on the posterior wall of the duodenum within the scope of form-and function-preserving gastric surgery. Technic and 1st results].

By combining different methods available in modern gastric surgery, we have developed a new procedure in surgical treatment of the complicated ulcer of the posterior duodenal wall. Our new technique allows the radical resectioning of the ulcer and includes all the advantages of nonresectioning operations in form- and function-preserving surgery. The technique of open anastomosis with an one-row, one-layer suture only slightly injures the gut that is to be anastomosed and thus eliminates complications in the healing process. The pylorus is completely preserved. The great advantages of avoiding gall reflux into the stomach, of preserving its total capacity, and of preserving the possibility of a portioned evacuating of the stomach can not yet be fully estimated.

Duodenal Ulcer↗
PubMed1978

[Experimental longterm cannulation of the stomach (author's transl)].

The construction and use of a new cannula for the long-term cannulation of the stomach in experimental surgery is described. The major attribute of the gastric fistula is the simplicity of technical management and the advantage to avoid irritation of the animals as much as possible.

Animals↗
PubMed1978

[Collecting methods for pancreatic juice in long-term research in the non-anesthesized dog].

Comparison of various methods of collecting pancreatic juice in long-term experiments shows that there is no ideal procedure. The authors themselves obtained the best results by help of the duodenal cannula according to Tuckermann and Thomas, which is implanted in the duodenum opposite to the duodenal papilla. Using this cannula it is often possible with sufficient skill and patience to cannulate the duodenal papilla from the outside and to gain pancreatic juice from the awake dog in an exact manner. Among the pouch techniques the best is the method according to Herrera.

Animals↗
PubMed1977

[Hemothorax after abdominal vagotomy. Diagnostic problem].

Selective or selective-proximal vagotomy has increased in preference as surgical treatment for uncomplicated duodenal ulcer disease. An unusual immediate complication of transabdominal vagotomy is the hemothorax. Few cases of this complication have been reported in literature. Our case represents a variation with simultaneous presence of a both-sided hemothorax. Although the exact etiology of this complication remains obscure, we try to explain this spontaneous hemothorax by operative injuries of subpleural vessels.

Abdomen↗