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Biomedical subjects

H Hildmann

Publications and source records attributed to H Hildmann.

At least 37 records · Page 2Linked to original sources
PubMed1987

[Lymphoscintigraphic studies of regional lymph vessels in patients with head and neck tumors].

Lymphatic drainage was followed with Tc lymphoscintigraphy. Micrometastases in head and neck cancer cases cannot be detected. The drainage pattern is highly variable and does not allow prognostic conclusions in tumors as demonstrated for the parasternal pathways. The method helps to determine the side and extent of a neck dissection prior to surgery as well as follow-up postoperatively. The development of lymphedema can be detected early in order to start treatment by manual lymph drainage.

Head and Neck Neoplasms↗
PubMed1986

An autoradiographic study of bone grafts in small animals.

Bone remodelling was studied in allografts and isografts by means of autoradiography. Collagen and proteoglycans of the organic bone matrix were labelled with H-3 amino acids and S-35 sodium sulphate. The principles of primary bone formation are followed in graft remodelling as well. Matrix breakdown and reformation are carried out by mononuclear cells. Components of the original matrix can be seen in osteoclasts, perivascular cells, osteoblasts, young osteocytes, and in new bone. The label allows tracing of these components and proves their reuse.

Amino Acids↗
PubMed1985

Tympanoplasty in children and anatomical variations of the epipharynx.

Short-term results or post-operative check-ups after tympanoplasties in children and adults are compared. There is no higher incidence of recurrent perforations in children. The distribution of air cells in adults and children does not vary, indicating that anatomic variations, rather than disease, are responsible for the sclerosis in the mastoid. Anatomic variations of the epipharynx might influence ventilation. Correlations between the width of the epipharynx and the distance between molars and premolars are shown, as is an inverse relation between the height of the palate and the height of the septum. These observations might be important for a prognosis in patients with ear disease.

Adolescent↗
PubMed1985

[Indications for surgical intervention in occult paranasal sinusitis in the child].

Sinus surgery, including antroscopy, is rarely indicated in children because radiological changes and their histological correlates often disappear spontaneously. In this paper we report the follow up of 17 children who underwent sinuscopy for an occult sinusitis with radiologic opacity of the maxillary sinuses. Even though considerable inflammatory reactions were seen normal x-rays were found in 68% one year after endoscopy.

Child↗
PubMed1985

[Submucous turbinate resection].

This article describes the authors' experiences on submucous resection of the turbinate bone in chronic hypertrophic lower turbinates. Similar to the procedure in septoplasties, this surgery preserves the mucosa and its physiological properties. The technique is facilitated by an amazingly low tendency to bleeding. 70 patients were followed up post-operatively. More than 70% reported a marked improvement of nasal breathing. No serious complications were seen.

Adolescent↗
PubMed1984

[Intratympanic course of the internal carotid artery as an accidental finding of ear surgery and as a roentgen diagnostic problem].

The rare anomaly of an intratympanic course of the internal carotid artery is, like the equally rare aneurysm of this artery, a differential diagnosis of tumours of the middle ear. A biopsy would lead to obvious complications. Petrous bone tomography, even using the most modern spiral type of movement, is of limited value because of the difficulty in interpretation and plays little part in the diagnosis as compared with arteriography.

Adult↗
PubMed1984

[Value of isotope diagnosis in diseases of the ENT area. Status, development and trends].

The nuclear medical diagnostic procedures listed in this article demonstrate the continual change in the significance of modern and recent techniques. The definition of the current status may be as short-lived as some radioisotopes. The tendencies are determined by aspects of radiological hygiene and the development of new technical procedures and the preference of in-vitro-examinations over in-vivo-diagnostic. On the other hand progress in immunology using labelled antibodies opens new possibilities in diagnosis and therapy. Although these possibilities are still somewhat visionary, they have already been translated into reality by experiment. For examination of thyroids further progress in sonography can be expected. In special problems tests using iodine isotopes with short half-lives and consequently lower radiation exposure will be used. At the moment the combination of technetium scintigram with sonography seems optimal and should if possible applied by the same hand. Scintigraphy of salivary gland and of cerebrospinal fluid have their unquestioned position. Brain scintigraphy has lost its importance but may reappear as an examination method using specially labelled agents for research of cerebral metabolism. The position of bone scintigraphy is similar. Its use is still justified when searching for skeletal changes which may not be seen in classical radiology. The knowledge of disturbance of local osseous metabolical disturbances does not give a specific information on the cause but demonstrates the site of disorder. Contrary its present ranking, important developments are to be expected from tumour scintigraphy. Isotope angiography, isotope lymphography and ventilation scintigraphy are to be employed when special questions arise, especially in fundamental research and for controls of therapeutic concepts.

Angiography↗
PubMed1984

[Juvenile sinusitis maxillary sinusitis--an indication for sinusoscopy?].

Transnasal sinuscopy was performed in 43 children with maxillary sinusitis diagnosed by x-ray film. 70 maxillary sinuses were inspected. On 30 occasions a mucosa specimen was taken for histology. A comparison was made between endoscopical, radiological and histological findings. While we found a high degree of agreement between endoscopy and x-ray film, there was no correlation between endoscopic and histologic findings.

Adolescent↗
PubMed1983

[Differential diagnosis of glomus tumor].

The carotid artery and the jugular bulb can protrude into the middle ear, representing a chance finding during middle ear surgery. Since these vascular abnormalities do not require surgical treatment and incisions are dangerous, it will be necessary to differentiate between such conditions and Glomus tumours. Hence, preliminary diagnosis by angiography is a "must".

Adult↗
PubMed1982

[Anaesthetic problems with glomus tumors of the head and neck (author's transl)].

Anaesthesia and Postanaesthetic Course of Three Cases of Glomus Jugulare Tumor Were Studied. Pathophysiology and clinical features of this very rare tumor is discussed on a brief review of literature. After all localisation and dimension of this tumor can cause serious complications during operation and postoperative period. It must be considered that a safe operative and postoperative period is implied by carefull preoperative diagnostic management, special anaesthetic technics like controlled hypotension as well as postoperative intensive care.

Adult↗
PubMed1982

[Relations between the nasopharynx, eustachian tube distance and maxillary shape].

The results of measurements of the impressions of palate and nasopharynx are compared. While choanes, anterior and medial nasopharynx grow in relation to age, the posterior width correlates with measurements of the maxilla, especially with the distance of molars and premolars. This means that in persons with wide maxillary dimensions, a wide nasopharynx can be expected. This fact may influence the indication for tubal therapy and otosurgery, since a narrow nasopharynx implies poor conditions for the aeration of the Eustachian tube.

Adolescent↗
PubMed1982

[Isografts in middle ear surgery -- a histological and autoradiographic study (author's transl)].

Bone and cartilage isografts were implanted into the bullae of rats. Since there is no histoincompatibility between isogeneic animals this transplantation can be used as a model for studying autografts. The donor animal was labelled with H3-glycine. This amino acid appears in the intercellular substance of bone and cartilage. After grafting changes in the labelling pattern can be followed, by autoradiography. In bone grafts it remains unchanged until the intercellular substance is removed by osteoclastic cells and is partly reutilized in new bone formation. In cartilage grafts which did not remain totally vital the labelling pattern appeared unchanged during the time of observation. In areas of new formation cartilage, no activity could be demonstrated.

Animals↗
PubMed1982

[Steroid therapy in caustic lesions of the oesophagus].

Since controlled clinical studies on the value of steroid therapy do not exist, the discussion on its effect is still controversial. Several well documented studies on animals have been done since 1952. Based on these findings we can expect an inhibition of stricture formation in cases of moderate acid burns where the muscular layer is not or only slightly damaged.

Adrenal Cortex Hormones↗
PubMed1980

Ossification of the skull of the growing hamster. Autoradiographic observations.

Desmal ossification of the roof of the skull and of the alveolus of the incisor teeth of the mandible of growing hamsters and secondary ossification of the mandible were followed by autoradiography. Matrix production patterns as known from chondral ossification can be confirmed for desmal ossification as well. The secondary cartilage of the mandible shows an extremely low glycine turnover. These cells and the surrounding intercellular substance show different incorporation patterns as known for the epiphyseal cartilage of long bones. Secondary cartilage does not have growth functions for the mandible.

Animals↗
PubMed1980

Mustardé's otoplasty--evaluation of correlation between clinical and statistical findings.

Between 1973 and 1977 135 otoplasties were performed following the technique described by Mustardé in 1963. The follow up covered 105 of the cases (77,7%). The quality of the results and the validity of subjective and objective criteria for evaluation were evaluated statistically and compared with previous data. Three aesthetic groups were described by statistical methods. Shape and position of the corrected auricle were classified as good (53%), improved (35%), almost unchanged (12%), partial relapses 8 (7,5%), total relapses 6 (5,7%). In no case was a deteriostation observed. The head-pinna distance was measured at different points and compared with a normal sample. Calculating the head-pinna angle we found the normal range in only 33% (28 to 35 degrees), 40% were not symmetrical and in 39% an over-corrected or a moon-ear was seen, but patient and parents considered the latter cases pleasing. The influence of ear thickness on the result of the operation was investigated. In all failures (12%) the cartilage was thicker than 3,1 mm. in the triangular fossa and 3,4 mm. in the cavum. Since Mustardé's (1963) procedure is a suturing technique it is contraindicated in cases of macrotia. Experienced surgeons achieved better configuration of the antihelix and superior crus but were also responsible for 97% of the over-corrections.

Adolescent↗
PubMed1979

[Comparative studies of the endolymphatic sac and duct in embryonic skull (author's transl)].

The endolymphatic sac and duct were studied in 25 embryonic ears of humans between the 10th and 25th week of development. In the early stage the anlage develops as a protrusion medio-caudally from the utricle. During further development vacuoles appear within the connective tissue surrounding the duct and sac which eventually unite with the endolymphatic system enlarging the endolymphatic space as an answer of the connective tissue to the expansion and proliferation of the endothelium. In older specimens (fronto-occipital diameter: 40 mm) we find a tongue-like projection of the wall of the duct into the utricle known as the endolymphatic valve. This structure is covered with a thickened folded epithelium. It is stabilized by fibrous, cartilaginous, and bony tissue. Under normal conditions it therefore seems improbable that it can serve as a valve as supposed by other authors. The proliferation of endothelium and a concentration of blood vessels in this might indicate a higher metabolic activity with a biochemical filtering mechanism.

Ear, Inner↗