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H Hilse

Publications and source records attributed to H Hilse.

49 records · Page 3Linked to original sources
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Angiotensin-converting enzyme and other peptidolytic enzymes in human semen and relations to its spermatologic parameters.

Angiotensin-converting enzyme (ACE) and other enzymes of the renin-angiotensin system (RAS) occur in human semen in high activities. In contrast to bull ejaculates, not all zinc-dependent metallopeptidases are found to be in close correlation to the microscopically determined semen parameters; such a relationship was established only partly for the ACE. On the other hand, the RAS-dependent spermatozoa-bound enzymes, inclusive ACE, uniformly show negative correlations to the spermatologic parameters of human semen. These results, for the first time, point to different functions of the sperm-cell-bound (testicular) and of the seminal plasma (pulmonary) ACE activities.

Amino Acid Sequence↗
PubMedDate not supplied

Occurrence and potential importance of selected peptidases in bull ejaculates.

The zinc containing peptidases angiotensin-converting enzyme (ACE), neutral metalloendopeptidase (NEP), and leucine aminopeptidase (LAP) occur in bull ejaculates in high activities. These enzyme activities are in close correlation with some routineously determined semen parameters. These ejaculat parameters are used for quality classification and selection of ejaculates and are according to long term experience in good correlation to the male fertility. Semen quality related correlations could not be found for the dipeptidyl aminopeptidase (DPIV) and the aminopeptidase A (APA). Origin and possible function of the zinc containing peptidases in the semen are examined and discussed.

Animals↗