PubMed Health⌕ Search

Biomedical subjects

H Himmich

Publications and source records attributed to H Himmich.

31 records · Page 2Linked to original sources

[Low occurrence of delta agent infections in Morocco].

The incidence of delta infections in Morocco has been investigated to explain the high rate of severe hepatitis B (HB) observed in this country. The presence of delta antigen (D Ag) and antibodies to delta agent (D Ab) was tested by radio-immuno-assay in the sera from 85 HBs Ag positive patients, hospitalized in Casablanca: among them 57 suffered from acute or fulminant HB (12 deceased), 10 from chronic hepatitis and 18 from cirrhosis. Neither D Ag nor D Ab were found, excepted once in a patient with cirrhosis having shown the presence of D Ab. In contrast with the high endemicity of delta agent reported in other countries of North Africa, the incidence of delta infections seems to be very low in Morocco.

Hepatitis B↗

[True acute lobar pneumococcal pneumonia. Apropos of 51 cases].

In a retrospective study of 51 cases of acute pneumococcal pneumonia in Morocco, predominantly male subjects were affected without past medical history or pathology. The pneumonia was accompanied by an effusion in 18% and a bacteraemia in 11%. The most serious pneumonias were those complicated by meningitis (12% of cases) or septic shock (1 case). The presence of factors implying a poor prognosis (meningitis, septic shock, bacteraemia, advanced age) increases the mortality. Penicillin G is the antibiotic of choice. In low doses it is sufficient to achieve a cure in uncomplicated cases. In the severe forms, high doses do not always prevent a fatal outcome. The availability of a vaccine adapted for the African serotypes would enable people with special risk factors to be treated.

Adult↗

[Significance of the determination of lactic acid in the cerebrospinal fluid for the differential diagnosis of meningitis].

Measurement of cerebrospinal fluid lactic acid by an enzymatic test has been evaluated in 164 patients. The upper limit of normal CSF lactate was 300 mg/l. The CSF lactate level is useful for differential diagnosis between partially treated pyogenic meningitis and tuberculous meningitis. The increase of CSF lactate is not specific for meningitis and must be interpreted taking into account the clinical situation.

Adult↗

[Results of the surgical treatment of congenital mitral insufficiency].

The authors report 21 cases of congenital mitral incompetence undergoing surgery between 1972 and 1977. There were 3 operative deaths and 2 late deaths. Of the survivors, 10 had a good result and 5 a fair result. The factors influencing the results have been associated lesions (aortic stenosis and ventricular septal defects are more serious than atrial septal defects and abnormalities of origin of the left coronary artery), the type of repair (which is better if it seeks to correct the frequently complex valvular abnormality at all levels), and especially the degree of dilatation of the left ventricle. By contrast, age had no influence either on the operative risk or on the quality of the results.

Adolescent↗

[Fulminating streptococcal cellulitis. Importance of hypovolemic shock].

The authors report three cases. Hemostasis abnormalities and lowering of complement fractions was observed. Severe shock was lethal in two cases associated with severe local lesions. The role of unadapted treatment like corticosteroids and the lack of early penicillino therapy is discussed to explain this evolution.

Adrenal Cortex Hormones↗

[A study on antiretroviral treatment compliance in Casablanca (Morocco)].

OBJECTIVE: Compliance in HIV infection treatment is a major stake to give worldwide access to antiretroviral (ARV) treatment and especially in Africa. In September 2003, we undertook a study on compliance among HIV positive patients under antiretroviral treatment. These patients were included in a therapeutic educational program in the infectious diseases department of the Casablanca University Hospital (Morocco). The main objective of the study was to assess obstacles to compliance and to find possible solutions. DESIGN: A transversal investigation was made, based on questionnaires for patients under ARV treatment, chosen consecutively. The physician's and the educator's opinion on patient compliance was collected. RESULTS: Patients were between 21 and 65 years of age. Ninety-two patients were questioned and 89 analyzed. Treatment duration lasted from 2 to 67 months. Compliance according to educators was good (>90%) for 78 patients. The main obstacles for a good compliance were difficulty to respect administration schedule and the long distance between home and hospital, or the presence of adverse effects and other diseases. CONCLUSIONS: The role of the therapeutic educational program in improving compliance was largely highlighted.

Adult↗