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Biomedical subjects

H Hinderer

Publications and source records attributed to H Hinderer.

At least 19 recordsLinked to original sources
PubMed1979

[Legal aspects of acute alcoholic intoxication (author's transl)].

This paper deals with the legal aspects of acute alcoholic intoxication. Everybody is obliged in case of helplessness to organise help. Every doctor confronted with an acute alcoholic should careful examine the situation not to overlook other concomitant acute diseases.

Alcoholism↗
PubMed1978

[Suicide and its ethical and legal evaluation].

Suicide is--considering general principles to be judged both from ethical and legal viewpoints. Moreover special attentions has to be paid to the particularities of a single case and to the fact that these particularities do not recur. This is also true of the attempt to commit suicide. The "suicideprophylaxis" is of great social important. Attention has to be paid to the problems of a fellowman, who is possibly frightened of a think or who is ill and sees no wayout from his hopelessness. The author discusses regulations of the criminallaw such as indemniti in a case of suicide--if there was no "suicide and also a putting death against another person without there own consent" and the duty of help according to paragraph 119 StGB in an accident or represent a general danger. ("erweiterter Suicid")

Behavior↗
PubMed1977

[The responsibility of the surgeon (author's transl)].

Juridical survey upon the special problems of surgical carefulness. Emphasis is laid on the necessity of scientific and practical medical cooperation, respect for the patients life and the professional discretion.

Conscience↗
PubMed1975

Sensitivity tests of tumors to cytostatic agents. II. Investigation on human tumors.

Certain substances which influenced nucleic acid metabolism were found to have about the same cytostatic activity on human cells when measured in tissue culture experiments (cell numbers) or in short-term cultures (3-H-uridine incorporation in cell suspensions). By treatment with a dose of cytostatics corresponding to 10 times therapeutic dose, chemosensitive tumors can be distinguished from non-responsive tumors. By using this in vitro test system to investigate the sensitivities of 100 human tumors, it is shown that 28 of these tumors were responsive to adriamycin, daunomycin and Actinomycin D. Good agreement was observed between these in vitro results and the literature data on clinical therapy using these particular substances.

Antineoplastic Agents↗
PubMed1975

[Comparison of the results of radio gold therapy, cobalt 60 teletherapy and chemotherapy in 330 ovarian neoplasms].

From 1960 to 1972, 276 out of 330 cases of ovarian cancer were treated by different techniques of postoperative radiation therapy; 54 advanced cases underwent prospective chemotherapy. Radiogold intraabdominally administered (190 to 300 mCi), telecobalt (5000 rd) or the combination of radiogold and telecobalt was chosen for postoperative radiation therapy. Cyclophosphamide (Endoxan), prednisolone, and gestagenes (Prothil) were given as a long-term chemotherapy. The most successful technique of radiation therapy is confronted with long-term chemotherapy after three years (five years) of survival: Stage I a, b, c: Radiogold = 91.7% (66.7%), chemotherapy (only I c) = 100%. Stage II a, b: Radiogold + telecobalt = 47% (35%), chemotherapy = 85%. Stage III: Radiogold + telecobalt = 25% (0%), chemotherapy = 52%. Stage IV: Radiotherapy = 0%, chemotherapy = 25%. The absolute five-year survival without chemotherapy amounted to 23%. The mortality curve under chemotherapy shows a four-year survival rate of 88%, if tumor cells had been detected microscopically (ascites, omentum), but of only 30% after macroscopical verification of the tumor. Therefore, the maximally possible partial resection of the tumor is recommended in inoperable stages before the beginning of chemotherapy. "Prophylactic" long-term chemotherapy following macroscopically complete surgical treatment is recommended, whenever microscopical spread of tumor cells appears to be possible. In inoperable stages, chemotherapy ought to be applied prior to radiation therapy. In stages I a, b, c, and II a, postoperative irradiation with radiogold (100 mCi) and in stage II b additionally radiation teletherapy of the pelvis (6000 rd) is recommended.

Cobalt Radioisotopes↗