PubMed Health⌕ Search

Biomedical subjects

H Hodgson

Publications and source records attributed to H Hodgson.

29 records · Page 2Linked to original sources
PubMed1990

Hepatotropin mRNA expression in human foetal liver development and in liver regeneration.

A 569 bp probe against the beta-chain of hepatotropin was used to examine expression of RNA for this growth factor in human adult and foetal liver, foetal kidney and pancreas, and rat liver after partial hepatectomy. Low level expression of a 6 kb RNA occurred in human adult and normal rat liver. 70% hepatectomy increased expression, peaking at 10 h and returning to near normal levels 24 h after resection. The 6 kb band was strongly expressed in human foetal liver, as compared with adult, but not in foetal kidney or pancreas, suggesting a major role for hepatotropin in both foetal development and regeneration of the liver.

Animals↗
PubMed1979

Prostaglandins in umbilical plasma at elective caesarean section.

Prostaglandin E (PGE), prostaglandin F (PGF) and 13,14-dihydro-15-ketoprostaglandin F (PGFM) have been measured in umbilical cord plasma obtained immediately after delivery by elective Caesarean section. Umbilical venous plasma levels of PGE were significantly greater than the corresponding arterial levels (p less than 0.02); there were no significant arterio-venous differences for PGF or PGFM. In general, concentrations of PGFM exceeded those of PGE which in turn were greater than concentrations of PGF. Umbilical venous levels of PGE and both arterial and venous levels of PGF and PGFM were significantly greater after spontaneous labour with vaginal delivery than after elective Caesarean section.

Cesarean Section↗
PubMed1977

Measurement of menstrual blood loss in patients complaining of menorrhagia.

A study has been made of menstrual blood loss measured in 50 women with unexplained heavy loss (more than 80 ml). Twelve of these women had an average menstrual loss greater than 200 ml, five women in excess of 450 ml. There was no relation between the duration of menstruation and the total menstrual blood loss. Compared to women with normal menstrual loss there was no difference either in the proportion of total menstrual loss passed on each day of menstruation in women bleeding heavily (92 per cent of the total menses being lost in the first three days) or in the coefficient of variation for menstrual blood loss from one period to the next. There was a reduction in menstrual blood loss in the first period following uterine curettage but no effect thereafter.

Adolescent↗
PubMedDate not supplied

Studies in menorrhagia: (a) mefenamic acid, (b) endometrial prostaglandin concentrations.

Twenty-two women with unexplained heavy menstrual blood loss (average loss for two cycles of >80 ml) were treated with the prostaglandin synthetase inhibitor menfenamic acid during two consecutive menstruations. There was a significant reduction in menstrual blood loss on mefenamic acid therapy, the median loss being 137 ml before treatment and 76 ml while on treatment. Reduction in menstrual loss was achieved in 20 of the 22 patients but varied from a 2% to 78% reduction. The greater the menstrual loss before treatment, the more it was reduced on mefenamic acid therapy. Endometrial concentrations of prostaglandins E2 and F2 alpha in the follicular phase of the cycle were similar whether or not patients had menorrhagia. In the luteal phase, however, 6 of 14 patients with menorrhagia had higher endometrial prostaglandin E2 and F2 alpha concentrations than all 13 controls.

Adolescent↗
PubMedDate not supplied

Does reflexology impact on cancer patients' quality of life?

AIM: The objective of this study was to determine whether reflexology has an impact on the quality of life of patients in the palliative stage of cancer. METHOD: Twelve patients in the palliative stage of cancer with various tumour types were randomised into two groups. They were randomly assigned to receive either reflexology or placebo reflexology. All participants completed a linear analogue self-assessment scale relating to quality of life. All participants then received three sessions of either reflexology or placebo reflexology. The same person, a qualified reflexologist, provided the interventions for both groups. The participants were not aware of which intervention they were receiving. All participants then completed a second linear analogue self-assessment scale relating to quality of life. RESULTS: All participants felt that their quality of life had improved, even those who had received the placebo treatment. The reflexology group, however, reported more benefit than the placebo group. There was a significant difference (p = 0.004) between the reflexology group and the placebo group. CONCLUSION: This study showed that reflexology does have an impact on the quality of life of patients in the palliative stage of cancer.

Aged↗