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Biomedical subjects

H Hohmann

Publications and source records attributed to H Hohmann.

7 recordsLinked to original sources
PubMed2001

Relationship of intestinal parasites to the environment and to behavioral factors in children in the Bolikhamxay Province of Lao PDR.

From March to July 1998 the infection rates of 732 children aged below 15 years were assessed. The investigation was conducted in selected villages of the Bolikhamxai Province in Lao PDR. Socio-economic conditions and behavioral pattern were studied. The three soil-transmitted helminths, Ascaris lumbricoides, Trichuris trichiura and hookworm were found with prevalence rates of 67.14, 17.49 and 12.83%, respectively. Infection rates with other intestinal parasites were negligible. Of the children investigated, 56.7% harbored one and 20.45% more than one parasite. Except for hookworms, no statistically significant differences were found between genders. The probability of being infected with A. lumbricoides is associated with living in mountainous areas. For hookworms, infection is associated with staying in the plains. A river in the vicinity of the village is linked with the probability of being infested with Trichuris trichiura. Not to belong to a family with the ability to own expensive items increases the probability by almost two times of getting infested with A. lumbricoides. Unhygienic behavioral factors were important in increasing the probability of suffering from A. lumbricoides and T trichiura infection. Behavioral factors did not seem to be related to hookworm infections. It was concluded that after mass treatment, besides promoting the construction of toilets, it is also important to improve personal hygiene so that a lasting impact on the infection rate of the most prevalent parasites in Lao PDR could be achieved. Measures to control parasitic infections do not have to be postponed until a marked improvement of the economic situation has occurred.

Adolescent↗
PubMed1998

[Development of public health regulations for tattooing and piercing and their realization].

In the course of prevention of infectious diseases the Public Health office of the city of Bremen has made increase efforts to improve hygienic conditions in tattoo and piercing studios. Defined and practicable hygienic standards have been developed and formulated for and in cooperation with the studios. Supported by intense personal counselling of the studios the hygienic standards are now--after 6-9 months--widely accepted and increasingly observed in practice. This programme has been--as a crucial point--supplemented by intense information for the general public and the customers of the studios in order to support (and control) the practice of hygienic standards in tattooing and piercing also from this point of view.

Communicable Disease Control↗
PubMed1991

[Tetrachlorethene pollution--results of follow-up of neighbors of chemical dry cleaning establishments and current legal developments].

New legal provisions set a limiting value of 0.1 mg TCE/m3 air in flats. Follow-up examinations by the Public Health Office Bremen show again that so far this limit can not be complied with in flats adjacent to dry cleaners. Interviews with affected residents give no hint for a change in utilisation habits. The Upper House of the German Federal Parliament has taken the legislative initiative for a complete prohibition of TCE in consequence of the fundamental problem of limiting values.

Air Pollutants↗
PubMed1989

[The tetrachloroethylene burden of residents adjacent to chemical dry cleaning establishments].

The paper describes the concentration of tetrachlorethen (TCE) in the air of flats in Bremen adjacent to drycleaners and the resulting TCE concentration in the food and blood of the residents. The results indicate that--regardless of the cleaning system--a high TCE pollution must be expected with nearly everybody living next to a TCE dry cleaning shop. The currently propagated guiding value of 0.1 mg TCE per m3 of air or 0.1 mg TCE per kg of food can hardly be complied with--even after reorganisation in the drycleaning shop. The problem of guiding and limit values of TCE and possible alternatives to dry cleaning with TCE are discussed. The paper shows that Public Health Offices--in cooperation with other institutions--can make relevant contributions to investigations in the field of environmental health.

Air Pollutants, Occupational↗
PubMedDate not supplied

Applicability of four new antibodies for the detection of fetal nucleated cells out of maternal blood by FISH analysis.

The availability of fetal cells from the maternal peripheral blood opens up the possibility for a noninvasive prenatal diagnosis. Until now this prospect has been hampered by the fact that there are no highly specific antibodies to fetal cells. In the present study, four as yet untested monoclonal antibodies - 2G5, 3F9, EPO-R and Flk1 - were analyzed in view of their effectiveness to stain fetal nucleated cells. Therefore, 20 ml of peripheral blood from 40 women carrying a male fetus were collected in the 16th to 28th weeks of pregnancy. Mononucleated cells, enriched by density gradient, were stained with one of the four antibodies and isolated with magnetic cell sorting. Subsequently, fluorescence in situ hybridization with chromosome X and Y centromere probes was performed which allowed us to analyze the maternal or fetal origin of the enriched cells. For evaluation, 500 nuclei per case were examined. The antibody 3F9 detected 0.2 cells on average (n = 5), 2G5 1.2 (n = 11), EPO-R 1.6 (n = 10) and Flk1 1.8 cells (n = 8) with fetal specific Y-positive hybridization signals. The antibody against CD71 (n = 6) used as control gave no Y-specific signals. Considering these results, the tested antibodies, especially Flk1, appear to be more successful in detecting fetal cells than the commonly used CD71 antibody.

Antibodies, Monoclonal↗