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H Hubner

Publications and source records attributed to H Hubner.

6 recordsLinked to original sources

Mutagenicity testing of commercial insecticides administered per os.

Mutagenic activity of eight commercial insecticides previously tested with in vivo chromosomal aberrations test after intraperitoneal treatment, was studied with the same test using per os administration of pesticides. Chromosomal aberrations were analyzed in the bone marrow cells of Syrian hamsters. It was shown that six pesticides induced a statistically significant increase in the number of chromosomal aberrations: Bi 58 EC, Metasystox (I) forte, Sadofos 30, Nogos 50 EC, Foschlor 25 and Thiodan 35. These insecticides induced two main types of aberrations: chromatid gaps and chromatid breaks. Gamacarbatox and Propotox M were nonmutagenic in the test.

Administration, Oral

Chromosome studies in 3665 consecutive newborn children.

Results of chromosomal studies done on 3665 newborn children from central Poland have been described. As against a global incidence of 1:1022 for trisomy G and 1:1308 for the balanced translocation D/D in infants, the respective figures for the Polish infants were, 1:610 and 1:1221. Likewise, against the global incidence of 1:823 for the karyotype 47, XXY and of 1:1072 for the karyotype 47, XYY in infants, the respective incidence in the Polish infants was 1:626 and 1:939. The study has demonstrated also that the frequency of occurrence of the different widths of the C-bands had a distribution close to normal. The authors have noted that the children with chromosomal abnormalities were more frequently not as well developed at birth as were children with normal karyotypes.

Adult