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Biomedical subjects

H I Bader

Publications and source records attributed to H I Bader.

At least 19 recordsLinked to original sources
PubMed2001

Neutral proteases in crevicular fluid as an indicator for periodontal treatment intervention.

PURPOSE: To longitudinally determine if early therapeutic intervention, based on a positive neutral protease activity (NPA) assay score could effectively arrest the progress of periodontal disease destruction. MATERIALS AND METHODS: 63 periodontal sites which had previously undergone probing attachment loss were identified from among 31 previously treated adult periodontitis patients who were monitored during periodontal maintenance for an average of 3 yrs. Clinical levels of gingival inflammation and attachment levels and NPA assay data were collected at the beginning of each maintenance visit. When a site tested negative with the assay, routine Supportive Periodontal Therapy (SPT) was followed during the same appointment, while sites exhibiting a positive NPA score received more aggressive periodontal treatment. RESULTS: During the study period, 51 of 63 sites displayed at least one positive NPA score. Our protocol of administering periodontal treatment rendered at the visit showing a positive NPA score revealed that only 1 of the 51 sites lost > or = 1 mm attachment during the study period. The remaining 50 positive assay sites showed an overall gain of > or = 1 mm of probing attachment over the course of the study. 12 of 63 sites consistently tested negative for neutral protease enzyme activity and remained stable, although 9 of these sites exhibited bleeding on probing (BOP) at least once during this study. Initial group mean probing attachment measurements were 5.6 mm for NPA negative and 5.7 mm for NPA positive sites.

Adult↗
PubMed2000

Use of lasers in periodontics.

Although lasers have been used in periodontal therapy for 10 or more years, clinicians have barely begun to tap the enormous potential of this form of therapy. The relative lack of pain, ease of use, and site specificity of the laser make it an ideal addition to the periodontist's armamentarium. Applications now are being developed for a broader range of wavelengths that will offer useful, predictable, and comfortable therapy for managing the periodontal patient.

Dental Equipment↗
PubMed1999

Long-term monitoring of adult periodontitis patients in supportive periodontal therapy: correlation of gingival crevicular fluid proteases with probing attachment loss.

The aim of this retrospective study was to determine if a chairside assay for neutral protease activity in gingival crevicular fluid (GCF) could provide an early indication of site-specific disease activity, as defined by probing attachment loss. Clinical measures and assay data were collected at 6-month intervals over an average period of 26 months (range from 24 to 36 months). 38 subjects were selected from a pool of previously-treated chronic adult periodontitis patients who were in periodontal maintenance at intervals of 3 to 6 months. GCF samples were collected from a total of 71 tooth sites exhibiting prior attachment loss, and analyzed for neutral protease activity (NPA). Positive BOP and positive NPA scores were classified as true positives if sites subsequently lost at least 1 mm of attachment over the next 12 months, as confirmed by linear regression analysis. As a predictor of breakdown, the NPA assay had an accuracy of 94% and a risk ratio of 37.6 as compared to values of 58% and 1.5 for BOP. When only the subset of sites > or = 7 mm were considered, the NPA assay had a calculated accuracy of 92% versus a value of 50% for BOP. These results indicate that the assay appears to differentiate between bleeding at sites exhibiting only chronic inflammation with no attachment loss and bleeding at sites undergoing active attachment loss.

Adult↗
PubMed1999

Comparative efficacy of a rotary and a sonic powered toothbrush on improving gingival health in treated adult periodontitis patients.

PURPOSE: To compare the efficacy of two powered brushing instruments (Rota-dent, rotary action instrument and Sonicare, a sonic instrument) for reductions of plaque and gingivitis in a treated adult periodontal patient population. MATERIALS AND METHODS: Forty patients, randomly selected from a pool of patients in periodontal maintenance after surgical periodontal treatment, completed this study. A split mouth, blind, crossover design was utilized in this 12-week trial with each patient acting as his/her own control. After subjects alternately brushed one-half of their mouths with each of the instruments; a crossover in the brushing pattern occurred at 6 weeks, with no wash out period. Single-blind clinical assessments were made by a calibrated investigator at six sites per tooth for contralateral incisors, premolars and molars at baseline, 6 and 12 weeks. Gingival Index (GI), Plaque Index (PI) and Papillary Bleeding Index (PBI) were determined. A prophylaxis was done for all subjects after baseline recordings. RESULTS: Mean percent reductions from baseline for GI, PI and PBI at the end of 6 and 12 weeks were 75.0%, 68.9%, 73.4% and 76.4%, 69.9%, 74.0%, respectively for the rotary instrument, and 57.7%, 53.3%, 54.3% and 57.7%, 53.6%, 54.7%, respectively for the sonic brush. One-way ANOVA indicated that the rotary instrument was significantly more effective (P < 0.005) than the sonic brush in removing plaque and reducing gingivitis in treated adult periodontitis patients.

Adult↗
PubMed1997

Clinical advances of the pulsed Nd:YAG laser in periodontal therapy.

Since the Nd:YAG laser was first developed in the 1960s, its spectrum of capabilities has continued to expand in the medical field. In dentistry, treatment of both hard and soft tissue has been affected, with the most noticeable change occurring in the management of periodontal disease. The learning objective of this article is to review the utilization of the pulsed Nd:YAG laser (American Dental Technologies, Southfield, MI) in the management of periodontal disease. Cases are presented to document the clinical aspects, and directions of future research are indicated.

Clinical Trials as Topic↗