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Biomedical subjects

H I Goldman

Publications and source records attributed to H I Goldman.

At least 19 recordsLinked to original sources

Respiratory health status of children in the eastern Transvaal highveld.

A study was undertaken to determine if there were detectable effects on the respiratory health status of children resident in the eastern Transvaal highveld as a consequence of their exposure to community air pollution, comparing them with children in areas ostensibly less polluted. A prevalence study was conducted in white schoolchildren from 11 schools in the eastern Transvaal highveld (1,031 children) and from 11 schools in non-polluted towns in the Transvaal (978 children). A questionnaire was completed by each child's mother, and height and weight were measured and spirometry recorded on a vitalograph. Cough, wheeze, asthma and chest illnesses were more frequently reported from polluted areas compared with non-polluted areas, taking into account parental smoking and home cooking fuel (odds ratios 1.34, 1.20, 1.15 and 1.88, respectively). After correcting for age, children in the polluted area were 0.83 cm shorter (P = 0.035). However, there were no significant differences in forced vital capacity and forced expiratory volume in 1 second after standardising for height, age, parental smoking and home cooking fuel. We conclude that, in children, exposure to pollution in the eastern Transvaal highveld may cause respiratory symptoms and chest illness and may affect height but does not measurably affect lung function, as assessed by spirometry.

Air Pollution

Feeding and necrotizing enterocolitis.

Twenty-six infants had necrotizing enterocolitis (NEC) in the neonatal unit of the Long Island Jewish-Hillside Medical Center, New Hyde Park, NY, between 1964 and 1976; 25 of these cases occurred between 1973 and 1976. The relationship of feeding practices to this clustering of NEC cases was investigated in two ways: (1) A 10% sample of all admissions, 1964 to 1976, was studied. A striking correlation was found between the yearly incidence of NEC and the percentage of infants in that year who had received large increases in daily feeding volume. The highest mean daily feeding volume occurred in 1974 and 1975, the two years of peak NEC incidence. (2) The feeding records of the 26 NEC cases were studied. Thirteen NEC patients had had large increases in feeding volume within two days of NEC onset. Seven others received greater than 150 mL of formula per kilogram per day prior to NEC onset. Rapid increase in feeding volume and the use of large volumes are suggested as important etiologic factors of NEC.

Enteral Nutrition

Anaemia, iron deficiency and exercise: extended studies in human subjects.

1. Ventilation and cardiac frequency were measured during repeated treadmill exercise in three healthy subjects over 36 weeks, before, during and after iron-deficiency anaemia was produced and after iron treatment. The haemoglobin and 2,3-diphosphoglycerate concentrations and the oxygen-binding (P50) were measured. 2. There was an inverse relationship between the haemoglobin concentrations and the 2,3-diphosphoglycerate concentrations and the P50 values. 3. The mean cardiac frequencies during the fourth to tenth minutes of exercise showed a negative correlation with the haemoglobin concentrations in all three subjects, and the mean minute ventilations in two of them.

Adult