PubMed HealthSearch

Biomedical subjects

H I Jones

Publications and source records attributed to H I Jones.

17 recordsLinked to original sources

Successful control of a school based measles outbreak by immunization.

In an outbreak of measles in North Wales centred on a secondary school in 1991, 74 cases occurred over a period of 51 days. Before the outbreak started, 27% pupils did not have a history of measles or immunization and were considered susceptible. Active case finding and identification and vaccination of susceptible contacts commenced after the fourth generation of cases and further reduced the pool of susceptible schoolchildren from 17%, at the onset of the vaccination campaign, to 8%. A fifth generation of cases did not occur. Delays in diagnosis (mean 2.8 days) and notification (mean 6.1 days) hampered control. There was no evidence of primary vaccine failure (observed vaccine efficacy 97%). Sixty-nine (93%) cases were considered preventable. Reasons for the apparent success of the intervention are discussed.

Adolescent

Salmonella enteritidis phage type 4 infection: association with hen's eggs.

Epidemiological and microbiological investigation of the four outbreaks of Salmonella enteritidis phage type (PT) 4 that occurred in Wales in 1988 implicated foods containing shell eggs from hens as the vehicle of infection. In a case-control study of sporadic cases there was a significant association between infection and egg consumption in the 3 days before illness. These findings provide data to support the warnings from the Departments of Health in the United Kingdom about risks of infection from eating raw or undercooked hens' eggs.

Adult

Notes on parasites in penguins (Spheniscidae) and petrels (Procellariidae) in the Antarctic and Sub-antarctic.

Blood smears were examined from 143 penguins of four species (Aptenodytes patagonicus, Eudyptes chrysolophus, E. schlegeli, and Pygoscelis gentoo) from Sub-antarctic Macquarie Island and Heard Island. No blood parasites were reported. The vectors of Hepatozoon albatrossi (reported from three species of albatross) are probably shared by penguins, and it is suggested that the latter are not susceptible to infection with this protozoan. Cestodes of the genus Tetrabothrius were present in large numbers in the intestines of 17 Antarctic petrels (Thalassoica antarctica), and evidence is presented indicating that euphausiid crustaceans may be intermediate hosts.

Animals

Intestinal parasites and bacteria in Aboriginal children in South West Australia.

In a study of intestinal parasites in 697 Aboriginal children under the age of 6 years in South-west Australia, Giardia lamblia was recorded in 26% and Hymenolepis nana in 13.9%. G. lamblia infections occurred above 4 months of age, and H. nana infections above 18 months of age. There was a close correlation between infection with these two species (chi 2, P less than 0.001). Campylobacter jejuni, the predominant bacterial species recorded, was isolated in 2.3%, and was related to bowel symptoms in one child. G. lamblia was more prevalent in the country areas than in the Perth metropolitan area (chi 2, P less than 0.05. H. nana was more prevalent in children whose weight was below the third percentile (chi 2, P less than 0.02), and in those with diarrhoea (chi 2, P less than 0.01). There were strong correlations between low weight (below third percentile), a history of recent diarrhoea, and discharging ears.

Bacterial Infections

Hematozoa from montane forest birds in Papua New Guinea.

Blood smears were examined from 141 montane forest birds of 45 species in southeastern Papua New Guinea. Haemoproteus spp. occurred in 46 (32.6%), Leucocytozoon fringillinarum Woodcock, 1910 in five, Trypanosoma sp. in one and Haemogregarina sp. in one. Intensity of infection by Haemoproteus was highest in those avian species and families with the highest prevalence; increasing altitude had no demonstrable effect on the prevalence of Haemoproteus spp.

Altitude

Intestinal parasite infections in Western Australian Aborigines.

Giardia intestinalis (15.2%) and Hymenolepis nana (20.4%) were the two most frequently reported species in a study of intestinal parasites from 1683 Aboriginal people in Western Australia. Concurrent infection with the two species was statistically significant in the 0 to three years age group only (P < 0.01), and it is suggested that in older age groups the presence of one of these parasites may in some way inhibit the development of the other. Hymenolepis nana infection was more common in males than in females (P < 0.001). Hookworm and Strongyloides stercoralis infections were confined to the tropical north of the State. The total or near-total absence of infection with Ascaris lumbricoides, Trichuris trichiura and Entamoeba spp. (all frequent in eastern Australian Aboriginal communities) is noted, and possible reasons are discussed.

Adolescent

Cutaneous leishmaniasis in Western Australia.

A case of cutaneous leishmaniasis, which was successfully treated with metronidazole, is reported from Western Australia. Transmission is unlikely to occur in this country, but it is important to be aware that it may present in migrants or in travellers from endemic areas up to four years after inoculation of the parasite.

Adult

New species of Moaciria freitas 1956 (Nematoda: Heterakoidea) from Australian reptiles.

Moaciria sphenomorphi n. sp. is described from the skink Sphenomorphus gracilipes, Moaciria butleri n. sp. from the elapid snake Pseudechis australis (both from Western Australia), and Moaciria etnae n. sp. from the python Liasis childreni from Queensland. These species differ from one another and from M. alvarengai and M. icosiensis principally in the number and disposition of body and caudal papillae, and from M. freitasi in possessing caudal alae. M. butleri and M. etnae also differ from the other species in possessing a conspicuous three-pointed internal lip tooth, and all three new species possess a small median papilla within the posterior rim of the precloacal sucker.

Animals

Dioctowittus spp. Chabaud and Le Van Hoa 1960 (Nematoda: Adenophorea) from Australian snakes.

Dioctowittus denisoniae n. sp. from Denisonia punctata differs from D. wittei and D. chabaudi in the smaller size, lack of vestigeal male precloacal sucker, short egg-filaments, the presence of lateral expansions at the posterior end in the male, and in the expansions of the oesophageal tissue between the stichocytes. Dioctowittus sp. from Liasis amethystimus differs from the three described species in the posession of lateral lobes at both extremities.

Animals

Haemagglutination tests in the study of Ascaris epidemiology.

Haemagglutination tests using adult Ascaris suum antigen were performed on sera from 810 people from three areas in Papua New Guinea and East Timor. In the area with the highest childhood Ascaris infection rates and egg-counts (Kaul), titres were highest and remained high throughout life. There was a significant negative correlation between titre and eosinophil count, and it is suggested that high titres in adult life result from continuous usually unsuccessful reinfection, and that the declining egg-counts and infection rates with increasing age may be the result of an immune mechanism, and not decreased exposure. In the two other populations the less intense Ascaris infection was reflected in the lower titres, with no correlation between titres, infection or eosinophilia. Although the haemagglutination test as used here is unsuitable as a diagnostic aid, it is valuable in studying the epidemiology of Ascaris infections.

Animals

Toxocariasis.

Human infection with the larvae of the dog roundworm, Toxocara canis, occurs in Australia, especially in children, and though usually not serious, it can cause considerable damage if the larvae get into such organs as the eye.

Animals

A study of human intestinal helminthiases on Kar Kar Island, Madang Province.

This paper reports the results of an epidemiological survey of intestinal helminths in a village on Kar Kar Island, Madang Province. Samples of blood and faeces were collected from 320 people from all age-groups living in 51 houses in Kaul village. Three helminth species were recorded: Ascaris lumbricoides infections were highest and heaviest in childhood, and fell to low levels in adult life, the overall infection rate being 57%. More than 70% of the adult population were infected with Necator americanus, though almost all infections were light. 21% were infected with Trichuris trichiura, and all infections with this species were light. The parasitological findings were related to the haematological results, and the social and physical environmental factors affecting these findings are discussed. It is concluded that Ascaris infection is the principal cause of the high eosinophilia in the community.

Adolescent

Human intestinal helminthiases in East Timor.

In a study of 210 people from all age groups in the Venilale District of East Timor, 49% had Ascaris lumbricoides, 1% Trichuris trichiura and 67% hookworm infection. There were high Ascaris infection rates among some of the children, but the Trichuris and hookworm rates were almost uniformly low. The factors responsible for these rates are enumerated, and the complex interaction of the factors is discussed. The relative lack of shade and the well-drained limestone soil are probably in large measure responsible for the generally low helminth prevalence. Ascaris was the principal cause of eosinophilia. It was not possible to relate any other haematological or serological findings to the helminths. Apart from the high Ascaris infections in young children, it is not thought that these helminths constitute a heatlh problem.

Adolescent