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H J Assion

Publications and source records attributed to H J Assion.

16 recordsLinked to original sources
PubMed2001

[Paranoia erotica (de Clerambault syndrome) in affective disorder].

Erotomania is a rare delusional disorder usually associated with other psychic disorders, especially paranoid schizophrenia. The primary form without comorbidity is very rare. A case report is presented with characteristic features of the pure form of erotomania in a female patient that was nevertheless an affective disorder. A historical review is presented and the division of Clérambault's syndrome into primary and secondary categories critically discussed.

Adult↗
PubMed1999

[Folk medical practices in psychiatric patients of Turkish origin in Germany].

The treatment of Turkish patients is peculiar due to differences of socio-cultural background and speech. Magic conceptions of pathogenesis and nosogeny have a broad acceptance in a part of population. Magic faith healers, Hocas, are authorities to be consulted for treatment. In ritual acts they intend to stave off noxious influences and to strengthen the healing power with sacred formulas and through powerful objects. To investigate the importance, utilisation and attitude towards the Hocas of Turkish psychiatric patients living in Germany we conducted an interview with 55 psychiatric inpatients. Our findings were a reduced importance of Hocas due to influences of the Western culture and modern medicine. "Folk" medicine is still important for patients with psychic disorders and is used parallel to modern medical facilities.

Adult↗
PubMed1998

Neuroleptic malignant syndrome under treatment with antidepressants? A critical review.

Neuroleptic malignant syndrome (NMS) is a rare complication of treatment with neuroleptics. The pathophysiology is not fully known. A dopaminergic transmission block in the basal ganglia and hypothalamus is thought to be the pathophysiological mechanism of NMS. Several cases of NMS have been reported, precipitated by medication without a direct effect on the dopaminergic system. This Medline analysis concerns 23 cases of antidepressant-induced NMS reported in the literature with the differing pathophysiological hypotheses on the precipitation of NMS. The results indicate no hard evidence of an antidepressant-evoked NMS. However, various hypotheses assuming an disturbed balance of the dopaminergic and non-dopaminergic system may be relevant in animal studies, but are without clinically relevant proof presently. An antidepressant-induced NMS is a very rare complication on the basis of pretreatment with neuroleptics causing chronic dopamine blockade and elevated plasma level of neuroleptics due to comedicated antidepressants.

Antidepressive Agents↗
PubMed1997

[Paroxetine-induced neuroleptic malignant syndrome].

We report on a 22-year-old schizophrenic patient who attempted suicide and suffered an epidural hemorrhage. 16 days after the neurosurgical operation. After several weeks of treatment with promethazine, 1 day after intake of paroxetin he partially lost consciousness and developed extrapyramidal symptoms and vegetative disorders. Hyper-Ck-aemia up to 680 U/l was observed. Malignant neuroleptic syndrome (MNS) was diagnosed, which led to withdrawal of paroxetin and promethazine. He was put on dantamacrine and amantadine until the symptoms resolved. To date there have been few reports on MNS under tricyclic antidepressants and selective serotonin inhibitors. The influence of the central serotonergic system on the pathophysiology of MNS is discussed.

Adult↗
PubMed1997

[Coincidence of epilepsy and Asperger syndrome. Case report and review].

Asperger syndrome is an autistic disorder and was first described by Hans Asperger in 1944 without further acceptance in the literature over almost four decades. Following several publications in the 1980s, for the disorder became more widely known and was first introduced into ICD-10 and DSM-IV as a new diagnosis in 1988 and 1994, respectively. The etiology is unknown. We present a female patient with typical features of Asperger syndrome, suffering also from epilepsy and internal medical disorders. The associated diseases, diagnostic criteria and possible therapeutic options are discussed.

Adolescent↗
PubMed1997

[Asperger syndrome--an overview of diagnostic criteria].

Asperger syndrome is an autistic disorder which was first described in 1944 without further acceptance in the literature over almost four decades. Following several publications in the "80's, the disorder became more widely known. Asperger syndrome was introduced into ICD-10 and DSM-IV as a new diagnosis in 1988 and 1994, respectively. Several authors developed own criteria. Until now, some of the diagnostic criteria of Asperger syndrome remain controversial. We present a survey and a comparison of the criteria in the classification of DSM-IV, ICD-10 and of other authors. Six criteria are widely accepted, but there are divergent opinions about the criteria "intelligence" and "speech development".

Autistic Disorder↗
PubMed1997

[Neuroleptic malignant syndrome from treatment with antidepressives].

The neuroleptic malignant syndrome (NMS) is a rare complication in the treatment of neuroleptics. The pathophysiology is not fully known. A dopaminergic transmission block in the basal ganglia and the hypothalamus is thought to be the pathophysiological mechanism of NMS. There are some findings against the single role of dopamine receptor blockade: NMS is rare under neuroleptic treatment, although a strong dopamine receptor blockade is found even with a low dosis of neuroleptics. NMS can develop even after longterm treatment with neuroleptics and is not improved by dopamine agonists within the expected period. NMS may even develop when neuroleptics are reduced. Several cases have been reported of NMS precipitated by medication without a direct effect on dopaminergic system. Only rare case reports describe NMS under antidepressants. We report on all cases of NMS associated with antidepressants and present the different pathophysiological hypotheses on the precipitation of NMS.

Adult↗
PubMed1996

Hepatotoxic side-effect of clomethiazole.

We report on a patient with a history of alcoholism who developed hyperbilirubinemia induced by treatment with clomethiazole during two hospitalizations. After discontinuation of clomethiazole symptoms of cholestasis improved. Clomethiazole is a thiazole analogon and is chemically related to thiamine (vitamin B1). It can be administered as tablets, capsules, mixtures, and a 0.8% solution. Because of its sedative, hypnotic, and anti-convulsive effects it is used in the treatment of alcoholic delirium.

Alcohol Withdrawal Delirium↗
PubMed1996

Lymphocytopenia and thrombocytopenia during treatment with risperidone or clozapine.

The atypical antipsychotic clozapine is associated with several well-known abnormalities of blood cell count, whereas only rare reports are associated with the neuroleptic risperidone. This report describes lymphocytopenia and thrombocytopenia under treatment with risperidone which continued after changing to clozapine without other clinically significant abnormal hematological parameters. Within one week after discontinuation of both neuroleptics abnormalities of blood cell count reversed to the initial values. Abnormalities of lymphocytes or thrombocytes are rare side-effects under treatment with risperidone or clozapine.

Adult↗
PubMed1996

[Dementia-paranoid syndrome as the initial manifestation of AIDS. Case report and diagnostic overview].

A 33-year-old HIV-1-positive man developed dementia and a paranoid symptomatology with auditory hallucinations as the first manifestation of AIDS. The immunodeficiency syndrome is currently represented only by the immunohistochemical findings (CD4 216/microliters; CD4/CD8 ratio 0.12); no other manifestations of the disease are present. According to the literature about 15% of patients suffering from AIDS are likely to develop dementia during the course of the disease, usually after preceding opportunistic infections, severe systemic illness, or neoplasm. The manifestation of the disease solely by dementia is a rare phenomenon and represents, particularly if the incident of infection is cryptic, a diagnostic challenge.

AIDS Dementia Complex↗
PubMed1996

[Language regression to the mother tongue in polyglot patients with acute psychosis].

Three bilingual patients with schizophrenia are presented, who spoke almost exclusively in their native language during acute episodes of psychosis. Normal use of the foreign language, German, was again possible after remission of the acute symptoms. This phenomenon of regression is similar to speech disorders in patients with aphasia and is discussed with reference to recent biological findings.

Acute Disease↗
PubMed1996

[Panic attacks with cycloleptic course--differential diagnostic considerations in differentiating panic disorder from epileptic anxiety attacks].

This paper reports on a patient suffering from panic-attacks. A therapy with antidepressants and benzodiazepines was ineffective. The panic-attacks had a short duration and a cycloleptic course. Under the treatment with carbamazepine panic attacks improved. The differential diagnosis of panic disorder and epileptic panic attacks is discussed.

Anticonvulsants↗
PubMed1994

[Tardive dystonia. A rare neuroleptic-induced disease picture].

This paper reports on a case of spasmodic torticollis after longterm treatment with neuroleptics. This form of dystonia is called tardive dystonia to distinguish it from tardive dyskinesia. Its pathophysiology is unknown. Pathological changes are described in the basal ganglia. Increased signal was found on magnetic resonance imaging on both sides of the basal ganglia reflecting structural lesions. These structural changes, together with neuroleptic medication, represent predisposing factors for the manifestation of tardive dystonia.

Basal Ganglia↗