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Biomedical subjects

H J Black

Publications and source records attributed to H J Black.

18 recordsLinked to original sources
PubMed1987

Serum concentrations of amoxycillin in children following an oral loading dose prior to general anaesthesia: relevance for the prophylaxis of infective endocarditis.

A Working Party of the British Society for Antimicrobial Chemotherapy has recommended an oral regimen for adult patients at risk from infective endocarditis who require dental treatment under a general anaesthesia. The Working Party recommends oral amoxycillin 3 g 4 hours prior to general anaesthesia. This study shows that doses of amoxycillin previously recommended for the prophylaxis of infective endocarditis in children having treatment under local anaesthesia also result in adequate serum concentrations at the time of operation (14.34 mg/l +/- (1 S.D.) 8.64).

Administration, Oral↗
PubMed1984

Serum amoxycillin levels following oral loading dose prior to outpatient general anaesthesia for dental extractions.

Serum amoxycillin levels were measured 4 h after oral administration of a 3 g loading dose given prior to outpatient dental treatment under general anesthesia. A mean level of 8.49 mg/l +/- (1 S.D.) 5.07 mg/l of amoxycillin was obtained, which is adequate at the time of bacteraemia to protect patients susceptible to bacterial endocarditis. A second identical dose of amoxycillin was given following recovery from anaesthesia (mean 18.7 min) and was tolerated by 97.6% of patients.

Administration, Oral↗
PubMed1979

Development of a multifunctional drug file for hospital pharmacy computer applications.

The development of a multifunctional master drug file (MDF) which satisfies initial pharmacy data base requirements and has the capability to support increasingly sophisticated computer applications is described. The computerized purchasing, inventory, drug use review and formulary systems in a 1,100-bed teaching hospital were evaluated to determine which existing data fields should be included in the MDF, Functional requirements for the MDF and 27 data fields, each with its own particular specifications for programming, were identified. A method of data input was designed to create and maintain the file using keypunched Hollerith cards. Data input forms were designed to serve as coding documents for drug file data. Verification of all data in the file can be performed by running a program which lists the contents of each drug recorded. Based on 1975 salary rates, the total cost of the MDF development was $4,010; total time required was 640 hours. Approximately one hour per week is needed to keep the file contents up to date. File design specifications and contents are discussed, with special emphasis on the functional aspects of the MDF. The MDF successfully fulfilled the initaial pharmacy computer system requirements and has the potential to accommodate increasingly sophisticated applications.

Computers↗
PubMed1978

Duplicate prescription system to facilitate communication between a hospital pharmacy and community pharmacies.

A duplicate prescription system which enables a university hospital pharmacist to fill a copy of the prescription and return the original prescription to the patient for obtaining continuing supplies in his local community is described. The system is based on a prescription form and carbon duplicate with designated space for notations, and clarifications by the pharmacist. Instructions for use of the form and a statement that the prescription copy cannot be filled legally at any other pharmacy assures that the system will not be misused. The system helps assure that an initial quantity of medication is obtained by the patient before he leaves the hospital. Time spent by patients and prescribers in establishing initial and continuing supplies of medication is decreased under the system. The system is of substantial benefit to patients and health care providers.

Drug Prescriptions↗