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Biomedical subjects

H J Heite

Publications and source records attributed to H J Heite.

At least 19 recordsLinked to original sources
PubMed1980

Carnitine in seminal plasma: its significance in diagnostic andrology.

Carnitine estimation in human semen is of diagnostic value for epididymal function. About 95% of the free carnitine originates from the epididymis. In patients with euspermia the median value of carnitine is 7 +/- 3 mg%. The clinical significance of carnitine determination is demonstrated in azoospermia, varicocele, and obstructive azoospermia. In order to obtain a general picture of seminal plasma we ought not to rely only on fructose estimations but should also take into account those of the citrate and carnitine.

Carnitine↗
PubMed1978

[Citrate and acid phosphatase in the ejaculate in prostatic carcinoma and adenoma].

The simultaneous determination of acid phosphatase and citrate concentration in the seminal fluid obtained from 16 patients with prostatic adenoma showed normal values, 6 patiients with prostatic carcinoma (cytologically and histologically verified) however extremely low values. The difference between persons with prostatic cancer and those with adenoma became particulary obvious with both experimental results evaluated in the way of a twodimensional diagram. This clear separation of both clusters by the simultaneouse estimation of both biochemical parameters may possible get useful diagnostic significance.

Acid Phosphatase↗
PubMed1977

[Unusually high gamma-glutamyltransferase level in the semen and ist diagnostic significance].

A remarkable high activity of the enzyme gamma-glutamyltransferase (gamma-GT) is found in seminal fluid in 200 to 500 fold higher concentrations as found in blood serum. The seminal fluid gamma-GT originates expecially in the prostate gland and, to a smaller extent, in spermatozoa and secretion of testis and epididymis. Gamma-GT could be valuable to investigate the function of the prostate gland.

Acid Phosphatase↗
PubMed1977

[Effect of fluocortin butylester (0.75%) as an ointment in the pyrexal erythema test on human skin (author's transl)].

The antiinflammatory efficacy of butyl 6alpha-fluoro-11beta-hydroxy-16alpha-methyl-3,20-dioxo-1,4-pregnadien-21-oate (fluocortin butylester, Vaspit) as a 0,75% ointment was tested in comparison with 1% hydrocortisone acetate ointment in the model of the pyrexal erythema. Fluocortin butylester appeared to be significantly superior to hydrocortisone acetate.

Administration, Topical↗
PubMed1976

[Documentation in the hospital--methods and types of system (author's transl)].

Types of system and methods of documentation in clinic or hospital must be directed towards the object of the documentation: indexing or search documentation, informative or data documentation. Furthermore, a careful selection of the facts to be documented must be established, because a "complete clinical documentation" is unrealistic. Subtle knowledge of the methods of translation of medical facts into code numbers (coding techniques) is inevitable. Examples show how a very comprehensive data collection can be achieved in a short time from the documentation of only a few facts. Currently acquired data must be fed immediately for evaluation. The fact is criticized that some research promoters, when giving financial assistance for the installation of a data bank, shy away from providing the means for computer evaluation. In this way, useless "electronic data cemeteries" are produced. Consequently the demand, not only for the installation of data banks, but also to provide for their evaluation is deduced.

Diagnosis, Computer-Assisted↗
PubMed1976

[Sperm agglutination, sperm immobilization and sperm immunofluorescence test in married couples with unexplained infertility (author's transl)].

Thirty-four married couples with clinically unexplained infertility and normal spermiograms in all male partners were investigated for sperm antibodies by means of the sperm agglutination, sperm immobilization and sperm immunofluorescence test. In 50% of the couples, sperm antibodies were found in at least one of the partners and with at least one of the tests, e.g. ten times in the female partner alone, six times in the male partner alone, and once in both partners. The correspondance of the three tests was astonishingly low; it is assumed, therefore, that they indicate different types of antibodies. On the basis of the present investigations it is not possible to assess which type of antibody is responsible for the infertility of the female or male partner respectively. This seems only possible when the decrease of certain antibody types can be determined after a period of no antigen contact (avoidance of sperm contact) and when conception has taken place. The significance of autoantibodies against sperm in clinically healthy men with normal spermiograms remains open.

Antibodies↗
PubMed1975

[An immunofluorescent study of circulating sperm antibodies in humans (author's transl)].

1. By means of an indirect immunofluorescent technique with reference to Weller and Coons (1954), modified for spermatozoal immunofluorescence we found antibodies against spermatozoa in the sera of: 6 of 35 female partners of couples with unexplained infertility, 5 of 35 male partners of couples with unexplained infertility, 8 of 40 prostitutes, 8 of 18 men after orchitis and vasoresection. In contrast to these findings the sera of 20 fertile women, 25 fertile men, and 20 virgins showed negative results with the test mentioned above. 2. The site of the antigen-antibody reaction was mainly the spermatozoal tail and in the second place, the equatorial segment. 3. The immunoglobulins primarily belonged to the IgG and secondly to the IgA class. 4. Our results differ partly from the findings made by other authors perhaps on account of methodical differences. 5. The clinical relevance and associated problems are discussed.

Adolescent↗
PubMed1975

[Circulating sperm antibodies in prostitutes (author's transl)].

Spermatozoa antibodies are found uncommonly frequently in prostitutes both with regard to the spermatozoa immunofluorescence test and also sperm immobilisation. This is also true to a similar extent for the sperm immunofluorescence test in a group of women from infertile marriages, but not, on the other hand for the immobilisation test, in which the frequency of positive results in this group of women was significantly lower than in prostitutes. The outcome of comparative tests in virgins and fertile women were negative. The correlation of positive results in the sperm immobilisation test and in the sperm immunofluorescence test is strikingly small, so that a variable conclusiveness is to be assumed. Presumably, in the presence of sperm antibodies the probability of conception is reduced.

Adolescent↗