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Biomedical subjects

H J Hospers

Publications and source records attributed to H J Hospers.

9 recordsLinked to original sources
PubMed2005

Theory- and evidence-based intervention to improve adherence to antiretroviral therapy among HIV-infected patients in the Netherlands: a pilot study.

The objectives of this study were to describe and pilot-test a theory- and evidence-based intervention to improve adherence of HIV-infected patients with antiretroviral medication. Twenty-six treatment-experienced patients (>6 months on treatment) participated in a within-subject comparison design. Adherence was measured electronically with Medication Event Monitoring System (MEMS) caps for at least 5 months: 2 months before the intervention and 3 months during the intervention. MEMS data were used to measure the outcome of the intervention, but also served as feedback to participants during the intervention. Mean adherence during the month before intervention was compared to mean adherence during the third month of intervention. Data for the process evaluation were gathered through direct observation and semi-structured interviews. Adherence improved significantly during the intervention (Z = -2.1, p < 0.05). Mean adherence (percentage of prescribed doses taken within correct time interval) before the intervention was 81.8% compared to 92.5% during the third month of the intervention. More than 65% of the nonadherent patients (<95% adherence) before the intervention were adherent during the third month of the intervention. Both health care professionals and patients positively evaluated the intervention protocol and the electronic measurement of adherence. The only critique from some patients was the lack of userfriendliness of the MEMS cap and its medication container (size and shape). It can be concluded that the proposed intervention fits in standard care procedures, can be executed by trained HIV nurses, seems to improve adherence to antiretroviral medication, and is positively evaluated by the users. Large-scale and long-term research is warranted.

Adult↗
PubMed2003

[Transmural care for HIV-seropositive drug users: experiences from Southeast Limburg, the Netherlands].

In 1999 the decision was taken to start a transmural consultation service for HIV-seropositive drug users at the Consultation Office for Alcohol and Drugs [Dutch acronym: CAD] in Heerlen, the Netherlands. This consultation service was run by an AIDS consultant from Maastricht University Hospital together with the addiction physician from the CAD. In the period 1 November 1998-30 April 2002 29 HIV-seropositive drug users made use of this consultation service. Highly active antiretroviral therapy was prescribed to 23 patients during an average of 21 months (range: 4-51). Eighteen patients responded well to this therapy (viral load < 50 copies/ml) after 12-24 weeks of treatment and thereafter during 21 months. Direct observed therapy (DOT) was applied to 16 patients. Therapeutic failure due to poor compliance was observed in 3 patients. Two of them had initially been successfully treated with medication whilst under supervision but the treatment failed when they became responsible for taking their own medication. It seems that involving the Consultation Office for Alcohol and Drugs in the treatment and DOT has a favourable effect on the treatment of HIV-positive drug users.

Antiretroviral Therapy, Highly Active↗
PubMed2002

Chatters on the Internet: a special target group for HIV prevention.

This study examined characteristics of men who use gay chat boxes on the Internet, including dating behaviour and sexual risk-taking with sex partners who were initially met through chatting. Men on chat boxes were asked to complete a brief questionnaire on the Internet. The questionnaire contained questions on demographics, chatting-related variables, and dating and risk-taking sexual behaviour. The results show that a large majority of the 190 respondents reported actual encounters as well as sex with men who were initially met through chatting. Almost 30% of the respondents who engaged in sex with chat dates reported inconsistent safe sexual behaviour. The level of unprotected sex increased as the number of sex partners who were met through chatting increased. These results suggest that chatters on the Internet may be a new target group for HIV prevention. Further study is needed to gain insight into the feasibility of prevention efforts for this target group.

Adolescent↗
PubMed2001

Educational status and young Dutch gay men's beliefs about using condoms.

The higher levels of HIV risk behaviour that have been found in young gay men with lower socio-economic status (SES, among others defined as educational achievement) may result from unequal effects of safer sex interventions. We conducted semi-structured focus group interviews with an educationally diverse sample of 113 young gay men living in The Netherlands. The objective was to bring to light men's salient ('accessible') beliefs about using condoms since information about beliefs might facilitate the formulation of 'personally relevant' safer sex messages that enhance in-depth message processing. We found several educational differences in the areas of knowledge about HIV preventive behaviour, cognitive schemas about the factors involved in HIV transmission, perceived pros and cons of using condoms, perceived social pressure to use condoms and feelings of being in control of protective action. This may suggest that, for intervention efforts to be effective in motivating the diversity of young gay men to engage in safer sex, interventions should convey tailor-made messages that match recipients' educational degree. Several implications for the formulation of such messages are discussed.

Adolescent↗
PubMed1995

Determinants of safe and risk-taking sexual behavior among gay men: a review.

Since the outbreak of the AIDS epidemic, gay men have made impressive changes in their sexual behavior. Notwithstanding these changes, there are several studies that show considerable within-subject variability in risk categories, indicating that for a substantial number of gay men it is difficult to be consistently safe. A large number of studies have examined the relationship between sexual behavior and determinants of that behavior. This review reports and discusses the findings with regard to demographic, situational, behavioral, and psychosocial determinants.

HIV Infections↗
PubMed1994

Focus group interviews with risk-taking gay men: appraisal of AIDS prevention activities, explanations for sexual risk-taking, and needs for support.

Recently, several findings demonstrated an increase in high-risk sexual behaviour among gay men. This study conducted focus groups with gay men who engaged in risk-taking behaviour with casual partners. Three issues were addressed: appraisal of current AIDS prevention activities, explanations for sexual risk-taking, and needs for support. The results show that participants criticize current prevention efforts. The explanations for risk-taking behaviour contribute to a better understanding of the underlying processes related to sexual risk-taking. Participants' needs include unequivocal information on HIV and AIDS, more insight into the rationality behind safe sex directives, and more opportunities to discuss their difficulties regarding safe sex behaviour with peers.

Adult↗
PubMed1994

The effects of computer-tailored smoking cessation messages in family practice settings.

BACKGROUND: Many conventional health education materials, such as pamphlets and booklets, are designed to reach as wide an audience as possible; they are therefore often lengthy and contain information irrelevant to many consumers. Computer technologies allow sophisticated tailoring of messages targeted to individual patients and free of irrelevant information. METHODS: In two studies in North Carolina (study 1, N = 51; study 2, N = 197), adult cigarette smokers were identified from a cohort of family practice patients. Cigarette consumption, interest in quitting smoking, perceived benefits and barriers to quitting, and other characteristics relevant to smoking cessation were collected. Based on this information, smoking cessation letters were tailored by computer to individuals. Smokers were randomly assigned to experimental (tailored health letters) or comparison groups (generic health letter in study 1, no health letter in study 2). Smoking status was assessed again at 4 months (study 1) or 6 months (study 2). RESULTS: Both studies found statistically significant positive effects of tailored health letters among moderate to light smokers. In study 1, 30.7% reported quitting after 6 months vs 7.1% in the control group (P < .05); in study 2, 19.1% vs 7.3% (P < .05). CONCLUSIONS: Results from both studies indicate positive effects of computer-tailored smoking messages among moderate to light smokers. These findings are consistent with the focus of our computer-tailored program on psychological and behavioral factors related to smoking cessation. Smoking cessation outcomes may be enhanced by combining tailored messages with nicotine replacement therapies to treat physical dependency. Methods of tailoring health messages and incorporating the results into family practice are described.

Adult↗
PubMed1990

Attributions for previous failures and subsequent outcomes in a weight reduction program.

This prospective study examines the effects of causal attributions given to previous weight control failures on subsequent success in controlling weight. Adult participants enrolled in a weight control program were screened to identify those who had made previous weight reduction attempts through a formal program. Once identified, subjects (n = 158) were asked to make causal attributions for their previous failures. Subjects were then followed through the 15-week program to determine their degree of success. Subjects who attributed the cause of previous failures to stable, immutable conditions were more likely to have low expectations of success. Low success expectancies, in turn, were associated with lack of goal attainment through the program. The number of previous failures in formal weight control programs was associated with a perception of the respondents that previous failures had stable causes. Neither the number of former failures nor the attributions of their causes were directly related to goal attainment. Practice implications of the results are discussed.

Achievement↗