[Toxicity testing of contrast media for angiography in newborn rats. 3. Comparative testing of 4 media].
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Biomedical subjects
Publications and source records attributed to H J Kaufmann.
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In addition to eosinophilic granuloma, chondroma, osteochondroma, aneurysmatic bone cyst, and osteomyelitis, the differential diagnosis of primary costal tumors in children must also include Ewing's sarcoma. Radiologic diagnostic problems in localizing the tumor, in differential diagnosis, and the importance of imaging procedures are discussed with reference to a 16-year-old female patient.
Following the new classification of malformation syndromes genua recurvata in four newborns with pathogenetically different genetic syndromes (Larsen syndrome, Greig-polysyndactyly-syndrome, partial trisomy 10q and myelocele) have to be classified as a result of deformation. Genua recurvata in our patients are not symptoms caused by a specific syndrome, but have to be interpreted as a sequence.
In a prospective study 120 hips of preterm babies below 2,000 g were investigated by ultrasound studies in order to determine the distribution of the types according to Graf's classification. Compared with unselected newborns, preterm babies show a significantly higher incidence of ultrasound types Ib and IIa. The distribution of the ultrasound types of the hips of both groups is compared.
Report of a case with congenital right sided intrapericardial diaphragmatic hernia. This type of a congenital diaphragmatic hernia occurs only rarely. Until 1984 30 cases are recorded in the available literature.
Comparative radiologic/pathologic study of 45 newborns with primary and secondary pulmonary hypoplasia. 43 cases were proven at autopsy. From 9 cases with primary pulmonary hypoplasia, 7 could be identified by 3 independent observers. The roentgen criteria of primary pulmonary hypoplasia are evaluated and should serve in the future to clinically diagnose this condition.
Report of the 10th case of infantile cortical hyperostosis (ICH), diagnosed in utero. Because of a hydramnion noted in the 29th week of gestation, a 38 years old pregnant women was admitted to hospital. Ultrasound, radiographs of the unborn child and amninography were obtained. The radiographic and clinical signs of Caffey's disease are reviewed, and the literature particularly reports on prenatal onset are analyzed. The present "etiologic theories" are discussed.
This chapter presents a radiological classification of skeletal dysplasias, based upon the approved nomenclature of this group of disorders. This provides a practical approach to the problem of the radiological diagnosis of patients suffering from intrinsic diseases of the skeletal system, and should encourage universal adoption of the Paris Nomenclature of skeletal dysplasias in the future. Unclassifiable disorders eventually may be submitted to another conference of authorities in the field for the purpose of further refinement of the present classification.
Forty patients with tumors involving the skull base were selected on the basis of findings at high resolution computed tomography (CT). The reliability of demonstrating bony lesions with magnetic resonance imaging (MRI) and CT were compared. CT showed osseous lesions of the skull base better than MRI but was less sensitive in evaluating an associated inflammatory reaction or in defining intracerebral infiltration. Small cortical lesions were only demonstrable with CT. MRI was superior in defining the full extent of soft tissue infiltration. Arterial encasement was observed at MRI. The special advantage of Gd-DTPA lies in the additional possibility to differentiate vessels from tumor-like lesions and in en plaque tumors.
Some indications in which direct magnification radiography might be useful in the diagnosis of newborns and infants are illustrated. We believe direct magnification radiography is useful especially in respiratory distress syndrome, suspected aspiration of amniotic fluid and meconium, suspected pneumonia, mediastinal pathology, in newborns and infants and metabolic and inflammatory diseases of the skeletal system in older children.
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