Chemoprophylactic agent in schistosomiasis: 14,15-epoxygeranylgeraniol.
The occurrence of all-trans (-)-14,15-epoxygeranyl-geraniol in Pterodon pubescens Benth. is established, and its prophylactic activity against infection by Schitsosma mansoni demonstrated. Two other diterpenes present in the oil are inactive.
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