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Biomedical subjects

H J Neumann

Publications and source records attributed to H J Neumann.

At least 19 recordsLinked to original sources
PubMed1992

New polyolefin foil for 5-day storage of platelet concentrates (PC) collected by apheresis.

In a paired study 12 platelet concentrates (PC) of Fresenius AS-104 cell separator were stored in new polyolefin bags of Fresenius (LE2) and Fenwal PL-732 bags. On day 0 and after 3 and 5 days of storage pH, pO2, pCO2, cell counts, platelet morphology and aggregability, plasma glucose, lactate, LDH and beta TG were determined. The overall changes fell within the expected range. No relevant differences between the two bags could be detected, although a few parameters (pH, pCO2) are slightly but statistically/significantly different. It can be concluded that the new polyolefin bag is well suited for 5-day storage of PC's from the AS-104.

Blood Preservation↗
PubMed1989

[Stimulation of prenatal development in laboratory animals by nootropics].

Described in this paper is the use of nootropics for stimulation of prenatal development of laboratory animals. Investigations, in that context, led to the discovery of so far unknown and unexpected properties of this group of medicaments. Foetal weight gain, reduction of teratogenicity, and decrease in implantation loss proved to be some of them.

Animals↗
PubMed1989

[CHILD syndrome--a case report for understanding this rare genetic dermatosis].

CHILD syndrome in a 4 6/12 years old girl with manifestation of the typical unilateral ichthyosiform erythroderma and hypoplasia of the left arm and leg after birth is reported. The symptoms are listed in a table for comparison to other publications. The moderate shortening of the mother's left arm has significance to the unclear mode of heredity. Local therapy with vitamin A acid brought a satisfactory result. Finally, a short reference is given to a new case from another kindred.

Child, Preschool↗
PubMed1988

Early evening ranitidine administration promotes faster duodenal ulcer healing.

In a prospective double-blind clinical trial, 141 patients with endoscopically diagnosed duodenal ulcer were randomly assigned to treatment with ranitidine 300 mg, taken either at 6 PM or at 10 PM. After 2 wk of treatment, 52 of 70 patients (74%) in the 6 PM treatment group had healed, compared with 32 of 64 patients (50%) taking ranitidine at 10 PM (p less than 0.01). After 4 wk, the cumulative healing rates were 100% and 94%, respectively, for the 6 PM and 10 PM treatment regimens. These results suggest that ranitidine, taken as a single daily 300-mg dose at 6 PM after dinner, provides more rapid duodenal ulcer healing than the same dose of the drug taken at 10 PM.

Adolescent↗
PubMed1987

Improvement of the safety systems in cell separators. The new safety concept for the cell separator AS 104 (Fresenius).

The new, extended safety requirements for cell separators call for a new generation of machines to address current safety needs. In order to ensure safe treatment, the complete safety concept is of decisive importance - this includes closed seal-less systems, continuous operation, fractions collected externally to the centrifuge, and pump tubings, connections and clamps which are color and direction coded. 'Human failure' as a cause of fault should be excluded for these highly technical appliances - for example, through the use of 'fail-safe' circuits, drip-controlled ACD flow by a separate adjustable pump, detection of damages to blood components by hemolysis control.

Blood Component Removal↗
PubMed1986

[Are animal experiments and clinical prevention of abnormalities possible?].

A important problem of the experimental teratology is the prevention of malformations. In this article first results are published of clinical prevention of clefts in hereditary burden families. Moreover described the present situation of the own experimental-teratological observations. The author found a new protective function against malformations by the nootropicum centrophenoxine.

Animals↗