PubMed Health⌕ Search

Biomedical subjects

H J Neumann

Publications and source records attributed to H J Neumann.

82 records · Page 5Linked to original sources
PubMedDate not supplied

Observations on simultaneous perilymphatic motions and cochlear microphonics suppression.

Very low frequencies interfere in the intact cochlea with higher frequencies and suppress these depending on the vibration phase of the low-frequency sound. Physiological functions of the body, mediated, for example, by the eardrum or perilymph coupling with the cerebrospinal fluid, cause a low-frequency pressure modulation of the perilymph, which generates a synchronous perilymphatic motion resulting from the unevenly distributed compliances in the cochlea. This slow streaming causes a displacement of the entire basilar membrane, with as a consequence a postponement of the operating point of the mechanoelectrical transducer as a result of the pressure drop in the helicotrema and the narrow apical cochlear turn. In this contribution, interference phenomena are described, which are caused by spontaneous contractions of the tensor tympani muscle and by respiration-synchronous perilymphatic flow. These two test signals have trapezoidal and triangular impulse functions. In both cases, as suppression pattern of the cochlear microphonics level-time function, the second derivative of the pressure-time function was observed. The suppression is found to lie between 1 and 2 dB. It depends on the level of the suppressed sound and shows a compressive nonlinearity.

Acoustic Stimulation↗
PubMedDate not supplied

[Reasons for the neglect of orofacial and alveolar malignancies].

In 1983 we treated 71 patients with orofacial and alveolar malignancies. In 25 cases the tumor had advanced beyond T2. An evaluation of their inpatient treatment data demonstrated that the lesion had been neglected by patient and physician. Our results clearly stress the need for information of the citizen and specialised postgraduate training of physicians and dentists about the early detection of orofacial malignancies.

Dental Care↗
PubMedDate not supplied

[Clinical experience with different modes of preoperative radiotherapy in advanced carcinomas of the tongue and the floor of the mouth].

In a controlled prospective study of 90 patients with locally advanced but operable epidermoid carcinomas (T2/T3N0-3M0) of the tongue and the floor of the mouth underwent 3 types of preoperative radiation: 1.5 x 5 Gy; 2.15 x 2 Gy and 3.5 x 2.5 Gy. The preoperative radiation led to a marked decrease of local recidives and to a lengthening of the recidive-free interval respectively. The type of preoperative radiation 5 x 5 Gy seemed to have the most favourable results. Otherwise the preoperative radiation had no advantages in regard to a better prevention of regional metastases and because of that there is no indication for it.

Carcinoma, Squamous Cell↗
PubMedDate not supplied

Successful treatment of disseminated facial verrucae with contact immunotherapy.

Disseminated flat warts are a common therapeutic problem in immunocompromised patients. However, disseminated infection on the face is, even in the immunocompetent host, a challenge. We report on a 14-year-old girl who had suffered from increasing eruptions of multiple disseminated verrucae planae et filiformes of the face for 18 months. As an alternative to silk-touch CO2-laser, contact cryotherapy or systemic immune enhancer we administered topical immunotherapy with diphenylcyclopropenone (DCP). The initial challenge with DCP 2% was performed on the forehead and the challenge was repeated weekly with DCP 0.01%. After four applications, the girl reported peeling of single warts on the forehead but more importantly at distant sites which had not received DCP. After eight weeks the patient's face was free of lesions. So far, the patient has remained free from relapse. This is the first case report of successful topical immunotherapy with DCP in disseminated facial verrucae planae and should be regarded as an effective therapeutic tool in this indication, emphasizing the great advantage of prevention of scarring of the skin induced by other therapeutic modalities.

Administration, Topical↗