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H J Priebe

Publications and source records attributed to H J Priebe.

49 records · Page 3Linked to original sources
PubMed1984

Evaluation of renal function.

The patient's history, physical examination, and routine urinalysis (including an expert assessment of the urinary sediment) are of paramount importance for the evaluation of a patient with possible renal dysfunction. The four tests most commonly used to establish the presence, extent, and the rate of progression of renal dysfunction are BUN, PCr, CCr, and 24-hour protein excretion. All four tests reflect glomerular function. However, their use to evaluate general renal function is justified by the structural and functional interdependence of tubular and vascular elements of the kidney.

Acute Kidney Injury↗
PubMed1984

Diuretics.

Explore the source record for details and available documents.

Acetazolamide↗
PubMed1981

Mechanisms of renal dysfunction during positive end-expiratory pressure ventilation.

Twenty-seven anesthetized dogs were studied to determine the effects of intrarenal blood flow distribution, hepatic congestion, and cardiac output (Q) and/or intravascular volume on renal function during ventilation with positive end-expiratory pressure (PEEP) of 10 cmH2O. In 10 dogs intrarenal blood flow distribution, as determined by the radioactive-microsphere technique, remained unchanged although PEEP caused a significant antidiuresis and antinatriuresis. The selective release of hepatic congestion during PEEP in eight animals by means of a vena cava to jugular venous shunt circuit did not restore renal function. Nine dogs were transfused with 25 ml/kg of autologous blood during PEEP. Although Q remained at only 70% of control, renal blood flow and renal function (glomerular filtration rate, urinary sodium excretion, urine output, osmolar clearance, and free water clearance) were restored to control values. Our results suggest that the impairment in renal function during PEEP is not caused by changes in intrarenal blood flow distribution, Q, or hepatic congestion, but rather by a decrease in intravascular volume.

Animals↗
PubMed1980

Antacid versus cimetidine in preventing acute gastrointestinal bleeding. A randomized trial in 75 critically ill patients.

Over a 15-month period, 75 critically ill patients at risk of acute gastrointestinal bleeding were randomized into two groups: one group (38 patients) received the H2-blocker cimetidine intravenously at an initial dosage of 300 mg every six hours, and the other group (37 patients) received antacid (Mylanta II) through a nasogastric tube at an intial dosage of 30 ml every hour. Gastric pH was measured hourly and titrated above 3.5. Upper-gastrointestinal-tract bleeding occurred in seven of 38 cimetidine-treated patients but in none of 37 antacid-treated patients (P less than 0.01). When antacid titration was added to the cimetidine regimen in four of seven patients with bleeding, all four stopped bleeding. Renal failure, sepsis, peritonitis, hypotension, respiratory failure, jaundice, multiple trauma, and major operative procedures were associated with an increased incidence of bleeding. Cimetidine does not adequately protect seriously ill patients from acute upper-gastrointestinal-tract bleeding. Antacid is better for this purpose.

Acute Disease↗
PubMed1980

Effects of renal and hepatic venous congestion on renal function in the presence of low and normal cardiac output in dogs.

We investigated the effect of acute renal vein and hepatic vein hypertension induced by partial balloon-occlusion of the abdominal inferior vena cava (AIVC-O) and the thoracic inferior vena cava (TIVC-O) on systemic and renal hemodynamics and renal function in 13 dogs anesthetized with pentobarbital. When a renal vein pressure of 13 cm H2O was induced by AIVC-O, cardiac output, stroke volume, central venous pressure, renal blood flow, and renal function (GFR, free water clearance, osmolar clearance, urine output, urinary sodium excretion, fractional sodium excretion) decreased significantly. When systemic hemodynamics were restored to control values by transfusion of autologous blood (mean of 9 ml/kg body weight) while renal vein pressure was kept elevated, renal function also was restored. A hepatic venous pressure of 13 cm H2O then was induced by TIVC-O. The effects on systemic hemodynamics and renal function were very similar to those observed during AIVC-O. When systemic hemodynamics were restored to control values by transfusion (mean of 9 ml/kg), while hepatic venous hypertension was maintained by TIVC-O, renal function also was restored. Despite significant changes in natriuresis and diuresis, intrarenal blood flow distribution, as determined by the radioactive microsphere technique, remained essentially unchanged throughout. We conclude that renal and hepatic congestion induced by partial AIVC-O and TIVC-O do not, per se, alter renal function significantly.

Animals↗