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Biomedical subjects

H J Seidlein

Publications and source records attributed to H J Seidlein.

At least 19 recordsLinked to original sources
PubMed1986

[The history of pharmaceutical science. 15. Development of pharmacy at the University of Greifswald between 1903 and 1968].

The paper is the first part of an extensive investigation about the development of pharmaceutical science at a university. The major purpose of this research is to show separately aspects of scientific organisation, the personel structure, the material-technical premise, teaching and research. Studies of the development of scientific organisation structures have carried out about several centuries, from the first teaching in the medical faculty in 1559, from the establishment of the section of pharmaceutical chemistry in the chemical institute in 1903, the foundation of the Institute of pharmaceutical chemistry in 1946 up to the "Department of Pharmacy Greifswald" in 1968.

Chemistry, Pharmaceutical↗
PubMed1984

[The quantification of drug information].

The necessary intensification of the information activity in the pharmacy service raises the question of the demand of each drug on the pharmacist as regards its information volume. The wealth of information on the application of drugs necessitates their differentiation and systematization. One differentiates between basic and additional information. On determining the frequency of occurrence of 21 pieces of additional information concerning 1321 pharmaceutical preparations, the mean information content according to Shannon [17] is calculated. The quantified results determine drug information as a statistical quantity from which their semantics for the receiver (user of the drug) must be abstracted. To consider the aspects concerning the contents and function of additional information, the weighting coefficients of 85 drug groups were calculated (by means of the triangular matrix method), and introduced. It is suggested to combine the numerical values of the statistically defined amounts of information with the quantities deduced from the meaningfulness in a parameter of the informational potential (IP) of pharmaceutical preparations. Finally, the authors convey their ideas of the benefit from, and the possible uses of, the IP.

Drug Information Services↗
PubMed1983

[Degree of gratification of needs in the use of drugs].

Studies aiming at determining the degree of satisfaction of needs in drug application are hindered by the fact that a clear-cut differentiation between the portions of drugs and the portions of counselling and of care during the process of satisfaction of needs is very problematic. The satisfaction of needs by prophylactic agents can be deduced from the ratio between the number of diseases for which a group of patients had been treated prophylactically and the number of diseases in an untreated control group. As to therapeutic agents, the decision on the satisfaction of needs depends, due to biological action limits of the pharmacon, on the extent at which the therapeutic accomplishment corresponds to the goal of needs. Goals of needs are defined, and evaluation criteria are established. The goals and the criteria are quantified using rank classifications and scales for grading. A model experiment confirms that it is possible --to evaluate the respective drug from the aspect of therapeutic accomplishment; --to determine the degree of satisfaction of needs by conforming to limiting guide values; and --to compare different drugs as to the satisfaction of needs by them.

Drug Therapy↗