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Biomedical subjects

H J Teske

Publications and source records attributed to H J Teske.

At least 19 recordsLinked to original sources

[Percutaneous ultrasonic-guided nephropyelostomy in tumor-caused block of urinary outflow].

A report is given on the method and results of ultrasound-guided nephropyelostomy which has been performed here for several years without open surgical intervention. The method has a low rate of complications and can be applied in severely ill patients, too. The problems of ureteral obstruction are quickly eliminated, even if the tumor has not been removed by chemotherapy, radiotherapy, or surgery. The authors report on 47 interventions performed in 36 patients.

Female

[Accuracy quota in fine needle puncture].

Percutaneous fine-needle biopsies guided by X-ray were performed in 100 patients utilizing the Nordenström canula. All cases have now been clinically controlled for at least 14 and up to 30 months. The follow up allowed further conclusions due to the dignity of histologically negative biopsies. Positive results on malignant lesions were obtained in 74% of cases. Our experience revealed that negative aspiration biopsies should be considered false negative until they could be confirmed by further investigations.

Abdominal Neoplasms

[The small Esssen high-pressure oxygen chamber for experimental animals (author's transl)].

A small translucent high-pressure chamber is introduced which has been exploited for local irradiation of tumour-bearing mice. The chamber has particularly proven to be valuable for high-pressure oxygen therapy together with simultaneous irradiation but can be used also for normal pressure and for gas other than oxygen. The chamber is shown during operation and a diagram illustrates design and technical data.

Animals

[The place of radiology in tuberous sclerosis (author's transl)].

Tuberous sclerosis is a rare disease in which hamartomas may be found in the brain, the retina, the skin and in other internal organs. The classic form of the disease showing mental retardation, epilepsy and adenoma sebaceum is easily recognised. Incomplete forms, however, can provide considerable diagnostic difficulties. Angiographically, appearances are found which cannot be differentiated with certainty from those of malignant tumours. Malignant tumours are very rare in this condition. Nephrectomy can be avoided if the diagnosis is made at an early stage. Two female patients are reported, in one of whom the diagnosis was made by renal angiography. Despite the presence of large tumours in both kidneys, these organs could be preserved by surgery. In the second patient there were also bilateral renal hamartomas, but surgery was not carried out. Both cases showed typical changes in the fingers and toes as well as intracerebral calcification, and in one the lungs were affected.

Adult

[Value of different systems of mammography records with regard to their exposure to radiation and their information content (author's transl)].

We learned from our examinations that, if there were optimum conditions, the combination Medichrome MR50 as a form of low dose method offers the same information content as the film without intensifying screens PE 4006. We found out that the discernibleness of details of 70 non selected mammographies which had each been taken by both systems was absolutely identical. By xeroradiography, however, a more precise representation of details, especially if there are microcalcifications, is possible because of its effect which renders the edges more visible. If the Medichrome low dose method was applied, the exposure to radiation of the breast was, depending on the density and width or the organ, only 1/12 to 1/14 of the dose measured if the film without intensifying screens was used. The exposure to radiation connected with xeroradiography is between these two values. We came to the following conclusion: the low dose method is recommended for routine mammographies, and only if there are special problems or if suspicious findings are to be clarified, xeroradiography is applied as supplementary examination method. Before using the film without intensifying screens, one should consider the high radiation exposure which, however, does not involve a greater information content.

Breast Neoplasms

[Comparison of the results from sonographic and lymphographic examination in retroperitoneal tumor formations (author's transl)].

Retroperitoneal sonographic (grey scale) and lymphographic examination of 51 patients was performed in a prospective study. With either method, an 1:1 correlation was detected in 47 patients (92%). In nine cases, sonographic examination directly revealed extended tumors, whereas lymphographically only lesions within the not-enlarged lymph nodes were represented at the same level. Defective lymph nodes with minimum tumorous affection, on the other hand, were not detectable by sonography. The indications resulting from these findings are defined more precisely with regard to the examinations.

Adult

[Reappraisement of lymphangiography in Hodgkin's disease. Comparison with 109 primary staging laparatomies (author's transl)].

Accuracy of lymphangiography was estimated in 109 patients with Hodgkin's disease by comparing its results with those of primary staging laparotomy. Accurate lymphangiographic diagnosis was achieved in 90% of involved and 85% of non-involved para-aortic lymph nodes, respectively. 11 of 12 false-positive cases were due to over-interpretation of lymph nodes exhibiting no enlargement but showing filling defects. Involvement without enlargement of lymph nodes appears to be a rare, even in young patients. Although staging laparotomy is of advantage, particularly when other methods fail to give reliable results, lymphangiography is still a valuable method for staging of Hodgkin's disease.

Diagnostic Errors

[Lymphographic demonstration of lymphnode fibrosis in Hodgkin's disease (author's transl)].

In 9 of 450 patients with Hodgkin's disease the fibrosis of retroperitoneal lymphnodes has been diagnosed by lymphangiographys. 5 cases with fibrosis were assigned to the clinical stage III B, and 4 cases to the stage IV B. According to the microscopic subclassification nodular sclerosis was diagnosed 7 times, the mixed type and lymphocytic depletion were found in 1 case. Lymphnode fibrosis developed spontaneously in 1 case, in three other patients following cytostatic treatment and in 5 patients after combination of radiation and chemotherapy. It has been concluded from these results that lymphnode fibrosis is induced mostly by therapy. Spontaneous fibrosis is a rare event in Hodgkin's disease.

Adult

[The value of sialography (evaluation of 251 cases) (author's transl)].

Sialography is of value for showing opaque or nonopaque stones in the maxillary glands. Possible complications (inflammation, abscess and fistula) can also be shown. Acute and chronic inflammation and sialadenoses show typical pictures. The diagnosis of tumors is less certain, genignity or malignity cannot be determined.

Acute Disease

The diagnostic value of sialography and scintigraphy in salivary gland diseases.

The diagnostic value of sialographic and scintigraphic investigations was compared in 169 patients. In this group were 75 inflammatory diseases and 49 benign and malignant tumours. Sialograms and scintigrams were examined by different physicians who had no knowledge of the clinical data of the patients. The scintigraphic diagnosis was considered correct if any abnormal finding was noted. The sialographic diagnosis was considered correct if the actual disease was diagnosed. In spite of the less stringent requirements for a correct scintigraphic diagnosis the sialographic technique was found to be superior. Radioactivity uptake curves over the salivary glands did not improve the scintigraphic diagnostic accuracy.

Humans

Diagnostic value of gallium-67 in malignant lymphoma.

The results of lymphangiography and other radiologic procedures are compared with those obtained by 67Ga scintigraphy in staging of 27 patients with Hodgkin's disease and 31 patients with non-Hodgkin's lymphoma. A high degree of correlation was found between lymphangiography and 67Ga scintigraphy. Exact localization, however, was only possible by lymphangiography. In some cases, the extent of disease found on scanning appeared to be smaller compared to radiography. Within the chest 67Ga scintigraphy and conventional radiography give almost similar results. Differentiation between neoplastic and inflammatory lymph node involvement is impossible.

Drug Evaluation

[The primary extranodal manifestation of lympho- and reticulosarcoma of the stomach].

We report about a group of 11 patients with primary lympho- or reticulosarcoma of the stomach in a group of 94 patients with Non-Hodgkin-Lymphomas. There were 5 patients with reticulosarcoma of the stomach among 44 patients with reticularsarcoma (11 percent) and 6 patients with primary lymphosarcoma of the stomach among a total of 50 patients with lymphosarcoma (12 percent). In most instances the diagnosis was made during surgery. At the time of diagnosis only 4 of the 11 patients had Stage IE disease. All patients who received intensive chemotherapy are living. Patients who died during the observation period had reticulosarcomas. They had not received any chemotherapy or treatment was discontinued early for varying reasons. Results are discussed in view of the diagnosis and treatment, suggestions for therapy are made.

Adult